Molekula
Pyrimethamine
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Pyrimethamine is an antiprotozoal medication used primarily to treat malaria and toxoplasmosis. It functions by inhibiting dihydrofolate reductase, disrupting folate metabolism in parasites. Available in powder form with a CAS number of 58-14-0, molecular formula C12H13ClN4, and molecular weight of 248.71 g/mol. Store at 2 to 8 °C. Hazardous: signal word Danger. Molekula supplies Pyrimethamine from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
Specifications available on request — see Documents below or contact our sales team.
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Transport Class | 9 |
| Packing Group | III |
| Acidity | Base |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Crystals |
| Melting Point | 233.5 °C |
| pKa | pKa = 7.34 (at 20 °C) |
| log P (octanol/water) | 2.69 |
Source: PubChem CID 4993 (HSDB, DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 46256850 |
| CAS Number | 58-14-0 |
| IUPAC Name | 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |
| EC Number | 200-364-2 |
| Molecular Formula | C12H13ClN4 |
| Molecular Weight | 248.71 |
| Exact Mass | 248.0829 |
| SMILES | CCC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)Cl |
| InChIKey | WKSAUQYGYAYLPV-UHFFFAOYSA-N |
| InChI | InChI=1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17) |
| PubChem CID | 4993 |
| UN Number | UN3077 |
| REACH Code | Y110 |
| HTS Code | 29335980 |
| Tariff Code | 2933599590 |
Safety & GHS
-
Health Hazard
GHS07
-
Serious Health Hazard
GHS08
-
Hazardous to the Environment
GHS09
Hazard statements
- H302 Harmful if swallowed
- H319 Causes serious eye irritation
- H341 Suspected of causing genetic defects
- H360D May harm the unborn child
- H362 May cause harm to breast-fed children
- H373 May cause damage to organs through prolonged or repeated exposure
- H411 Toxic to aquatic life with long lasting effects
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P263 Avoid contact during pregnancy/while nursing
- P273 Avoid release to the environment
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
- Chloridin
- Chloridine
- Chloridyn
- Daraprim
- Diaminopyritamin
- Ethylpyrimidine
- Pirimecidan
- Pirimetamin
- Pirimetamina
Frequently asked questions
What is pyrimethamine used for?
Pyrimethamine is primarily used as an antiprotozoal agent, commonly in the treatment and prevention of malaria and toxoplasmosis.
What is the chemical formula and molecular weight of pyrimethamine?
The chemical formula is C12H13ClN4 and the molecular weight is 248.71 g/mol.
How should pyrimethamine be stored?
Pyrimethamine should be stored at 2 to 8 °C, protected from light and moisture.
What grade of pyrimethamine does Molekula supply?
Molekula supplies pyrimethamine in research grade, suitable for laboratory use.
Can Molekula supply pyrimethamine in bulk quantities?
Yes, Molekula can supply pyrimethamine in bulk quantities—please contact our sales team for pricing and availability.
What documentation comes with a pyrimethamine order?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS), compliant with regulatory standards.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.