Molekula
Sofosbuvir
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Sofosbuvir is a potent antiviral nucleoside analog used primarily in the treatment of chronic hepatitis C virus (HCV) infections. It inhibits the HCV NS5B polymerase, preventing viral replication. This compound is a key component in direct-acting antiviral therapies for HCV genotypes 1 through 6. CAS 1190307-88-0, molecular formula C22H29FN3O9P, molecular weight 529.5 g/mol. Store at -15 to -20°C to maintain stability. The signal word is Warning, indicating moderate hazard. Molekula supplies Sofosbuvir from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to yellow solid |
| Impurity A | ≤0.10% |
| Impurity B | ≤0.10% |
| Purity (HPLC) | ≥99% |
| Heavy metals | ≤10ppm |
| Identification | Conforms to reference |
| Impurity C | ≤0.10% |
| Impurity D | ≤0.10% |
| Solubility | Easily soluble in ethanol, soluble in isopropnol and ethyl acetate, almost insolubbe in water and n-Heptane. |
| Residue on Ignition | ≤0.2% |
| Specific optical rotation | +37.0° to +41.0° |
| Water (KF) | ≤0.5% |
| Any individual impurity | ≤0.10% |
| Assay (HPLC on Anhydrous Basis) | 98.0% - 102.0% |
| Pentafluorophenol and SP (by HPLC) | Pentafluorophenol: ≤0.10%. SP: ≤0.10% |
| Thermal analysis | The melting endothermic temperature of the main peak should be within 118.0°C to 129.0°C |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | White to off-white crystalline solid |
| Water Solubility | Slightly soluble in water |
| pKa | pKa = 9.3 |
Source: PubChem CID 45375808 (HSDB, DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 90037490 |
| CAS Number | 1190307-88-0 |
| IUPAC Name | propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate |
| Molecular Formula | C22H29FN3O9P |
| Molecular Weight | 529.5 |
| Exact Mass | 529.1625 |
| SMILES | C[C@@H](C(=O)OC(C)C)N[P@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3 |
| InChIKey | TTZHDVOVKQGIBA-IQWMDFIBSA-N |
| InChI | InChI=1S/C22H29FN3O9P/c1-13(2)33-19(29)14(3)25-36(31,35-15-8-6-5-7-9-15)32-12-16-18(28)22(4,23)20(34-16)26-11-10-17(27)24-21(26)30/h5-11,13-14,16,18,20,28H,12H2,1-4H3,(H,25,31)(H,24,27,30)/t14-,16+,18+,20+,22+,36-/m0/s1 |
| PubChem CID | 45375808 |
| REACH Code | Y110 |
| HTS Code | 30039001 |
| Tariff Code | 3003900000 |
Safety & GHS
-
Serious Health Hazard
GHS08
Hazard statements
- H373 May cause damage to organs through prolonged or repeated exposure
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P402+404 Store in a dry place. Store in a closed container
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 7977, PSI
- EPCLUSA COMPONENT SOFOSBUVIR
- GS 7977
- HARVONI COMPONENT SOFOSBUVIR
- PSI 7977
- Psi-7977, gs-7977
- sofosbuvirum
- SOVALDI
- Sovaldi Access
- VOSEVI COMPONENT SOFOSBUVIR
Frequently asked questions
What is sofosbuvir used for?
Sofosbuvir is primarily used as an antiviral medication to treat chronic hepatitis C virus (HCV) infections.
What is the chemical formula and molecular weight of sofosbuvir?
The chemical formula is **C22H29FN3O9P**, and the molecular weight is **529.5 g/mol**.
How should sofosbuvir be stored?
Sofosbuvir must be stored at **-15 to -20°C** to maintain stability.
What grade or purity is available for sofosbuvir?
Molekula supplies sofosbuvir in **pharmaceutical-grade purity** suitable for research and development.
Can Molekula supply sofosbuvir in bulk quantities?
Yes, we can provide sofosbuvir in bulk, subject to regulatory compliance and order requirements.
What documentation comes with a sofosbuvir order?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and a **Certificate of Origin** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.