Molekula
Sofosbuvir
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Sofosbuvir is a potent antiviral nucleoside analog used primarily in the treatment of chronic hepatitis C virus (HCV) infections. It inhibits the HCV NS5B polymerase, preventing viral replication. This compound is a key component in direct-acting antiviral therapies for HCV genotypes 1 through 6. CAS 1190307-88-0, molecular formula C22H29FN3O9P, molecular weight 529.5 g/mol. Store at -15 to -20°C to maintain stability. The signal word is Warning, indicating moderate hazard. Molekula supplies Sofosbuvir from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to yellow solid |
| Impurity A | ≤0.10% |
| Impurity B | ≤0.10% |
| Purity (HPLC) | ≥99% |
| Heavy metals | ≤10ppm |
| Identification | Conforms to reference |
| Impurity C | ≤0.10% |
| Impurity D | ≤0.10% |
| Solubility | Easily soluble in ethanol, soluble in isopropnol and ethyl acetate, almost insolubbe in water and n-Heptane. |
| Residue on Ignition | ≤0.2% |
| Specific optical rotation | +37.0° to +41.0° |
| Water (KF) | ≤0.5% |
| Any individual impurity | ≤0.10% |
| Assay (HPLC on Anhydrous Basis) | 98.0% - 102.0% |
| Pentafluorophenol and SP (by HPLC) | Pentafluorophenol: ≤0.10%. SP: ≤0.10% |
| Thermal analysis | The melting endothermic temperature of the main peak should be within 118.0°C to 129.0°C |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | White to off-white crystalline solid |
| Water Solubility | Slightly soluble in water |
| pKa | pKa = 9.3 |
Source: PubChem CID 45375808 (HSDB, DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 90037490 |
| CAS Number | 1190307-88-0 |
| IUPAC Name | propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate |
| Molecular Formula | C22H29FN3O9P |
| Molecular Weight | 529.5 |
| Exact Mass | 529.1625 |
| SMILES | C[C@@H](C(=O)OC(C)C)N[P@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3 |
| InChIKey | TTZHDVOVKQGIBA-IQWMDFIBSA-N |
| InChI | InChI=1S/C22H29FN3O9P/c1-13(2)33-19(29)14(3)25-36(31,35-15-8-6-5-7-9-15)32-12-16-18(28)22(4,23)20(34-16)26-11-10-17(27)24-21(26)30/h5-11,13-14,16,18,20,28H,12H2,1-4H3,(H,25,31)(H,24,27,30)/t14-,16+,18+,20+,22+,36-/m0/s1 |
| PubChem CID | 45375808 |
| REACH Code | Y110 |
| HTS Code | 30039001 |
| Tariff Code | 3003900000 |
Safety & GHS
-
Serious Health Hazard
GHS08
Hazard statements
- H373 May cause damage to organs through prolonged or repeated exposure
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P402+404 Store in a dry place. Store in a closed container
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Quality certificates
Molekula Group is certified to ISO 9001:2015 (quality) and ISO 14001:2015 (environmental management), audited by a UKAS-accredited body. Both certificates are valid to 17 May 2028.
Synonyms
- 7977, PSI
- EPCLUSA COMPONENT SOFOSBUVIR
- GS 7977
- HARVONI COMPONENT SOFOSBUVIR
- PSI 7977
- Psi-7977, gs-7977
- sofosbuvirum
- SOVALDI
- Sovaldi Access
- VOSEVI COMPONENT SOFOSBUVIR
Frequently asked questions
What is sofosbuvir used for?
Sofosbuvir is primarily used as an antiviral medication to treat chronic hepatitis C virus (HCV) infections.
What is the chemical formula and molecular weight of sofosbuvir?
The chemical formula is **C22H29FN3O9P**, and the molecular weight is **529.5 g/mol**.
How should sofosbuvir be stored?
Sofosbuvir must be stored at **-15 to -20°C** to maintain stability.
What grade or purity is available for sofosbuvir?
Molekula supplies sofosbuvir in **pharmaceutical-grade purity** suitable for research and development.
Can Molekula supply sofosbuvir in bulk quantities?
Yes, we can provide sofosbuvir in bulk, subject to regulatory compliance and order requirements.
What documentation comes with a sofosbuvir order?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and a **Certificate of Origin** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.