Molekula
Macitentan
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Macitentan is a potent endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension. It functions by blocking endothelin, a substance that narrows blood vessels and increases blood pressure. Available with CAS number 441798-33-0, its molecular formula is C19H20Br2N6O4S and molecular weight is 588.27 g/mol. Store at -15 to -20 °C. Signal word: Danger. Molekula supplies Macitentan from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White solid |
| Assay | ≥99.5% |
| Single Largest Impurity | ≤0.1% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Melting Point | 134-136°C |
Source: PubChem CID 16004692 (DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 89988122 |
| CAS Number | 441798-33-0 |
| IUPAC Name | 5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(propylsulfamoyl)pyrimidin-4-amine |
| Molecular Formula | C19H20Br2N6O4S |
| Molecular Weight | 588.27 |
| Exact Mass | 587.9613 |
| SMILES | CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br |
| InChIKey | JGCMEBMXRHSZKX-UHFFFAOYSA-N |
| InChI | InChI=1S/C19H20Br2N6O4S/c1-2-7-26-32(28,29)27-17-16(13-3-5-14(20)6-4-13)18(25-12-24-17)30-8-9-31-19-22-10-15(21)11-23-19/h3-6,10-12,26H,2,7-9H2,1H3,(H,24,25,27) |
| PubChem CID | 16004692 |
| REACH Code | Y110 |
| HTS Code | 29335980 |
| Tariff Code | 2933599590 |
Safety & GHS
-
Health Hazard
GHS07
-
Serious Health Hazard
GHS08
Hazard statements
- H302 Harmful if swallowed
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
- H360 May damage fertility or the unborn child
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P263 Avoid contact during pregnancy/while nursing
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- ACT 064992
- Actelion-1
- C19H20Br2N6O4S
- Macitentan - Bio-X trade mark
- Macitentan (JAN/USAN)
- Macitentan (Standard)
- macitentanum
- Opsumit
- Opsumit (TN)
- OPSYNVI COMPONENT MACITENTAN
Frequently asked questions
What is Macitentan used for?
Macitentan is a pulmonary arterial hypertension (PAH) treatment used to improve exercise ability and delay disease progression.
What is the chemical formula and molecular weight of Macitentan?
The formula is C19H20Br2N6O4S with a molecular weight of 588.27 g/mol.
How should Macitentan be stored?
Macitentan should be stored at -15 to -20 °C to maintain stability and prevent degradation.
What grade of Macitentan does Molekula supply?
Molekula supplies Macitentan in research-grade quality suitable for laboratory use.
Can Molekula supply Macitentan in bulk quantities?
Yes, Molekula can supply Macitentan in bulk quantities—please contact our sales team for details.
What documentation comes with a Macitentan order?
Each order includes a Certificate of Analysis (CoA) and safety data sheet (SDS) with the shipment.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.