Molekula
trans-4-Hydroxy-L-proline
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
trans-4-Hydroxy-L-proline is a hydroxyproline derivative used in peptide synthesis and biochemical research. It is a key component in collagen structure and serves as a building block for protein studies. Available in powder form with a molecular weight of 131.13 g/mol, it has the CAS number 51-35-4 and molecular formula C5H9NO3. Stable at ambient storage conditions.
Molekula supplies trans-4-Hydroxy-L-proline in 25 g packs, from £57.60 inc. VAT. It is in stock for same-day dispatch. Every batch ships with a certificate of analysis, and safety data sheets are available in 6 languages. Larger quantities, up to multi-tonne, are quoted on request.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
In stock — same-day dispatch
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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25 g — £48.00 per pack ex VAT · £57.60 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to off white crystalline powder |
| Melting Point | 272-277℃ |
| pH | 5.5 - 6.0 |
| Water (KF) | <0.1% |
| Identification (IR) | Conforms to reference |
| Identification (RAMAN) | Conforms to reference |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Melting Point | 274 - 275 °C |
Source: PubChem CID 5810 (Human Metabolome Database (HMDB))
Identification
| Property | Value |
|---|---|
| SKU | 45298012 |
| CAS Number | 51-35-4 |
| IUPAC Name | (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid |
| EC Number | 200-091-9 |
| Molecular Formula | C5H9NO3 |
| Molecular Weight | 131.13 |
| Exact Mass | 131.0582 |
| SMILES | C1[C@H](CN[C@@H]1C(=O)O)O |
| InChIKey | PMMYEEVYMWASQN-DMTCNVIQSA-N |
| InChI | InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1 |
| PubChem CID | 5810 |
| REACH Code | Y113 |
| TSCA Listed | Yes |
| HTS Code | 2933.99.97.01 |
| Tariff Code | 2933998040 |
Safety & GHS
Precautionary statements
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P403+233 Store in a well ventilated place. Keep container tightly closed
- P405 Store locked up
- P501 Dispose of contents/container to an approved waste disposal plant
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Quality certificates
Molekula Group is certified to ISO 9001:2015 (quality) and ISO 14001:2015 (environmental management), audited by a UKAS-accredited body. Both certificates are valid to 17 May 2028.
Synonyms
- (4R)-4-hydroxy-L-proline
- 4-Hydroxy-2-pyrrolidinecarboxylic acid
- delta-Hydroxyproline
- hydroxy-L-proline
- hydroxyproline
- Hypro
- L-Hydroxyproline
- L-Proline, 4-hydroxy-, (4R)-
- trans-Hydroxyproline
- trans-L-Hydroxyproline
Frequently asked questions
What is trans-4-Hydroxy-L-proline used for?
It is primarily used as a building block in peptide synthesis and as a marker for collagen metabolism in biological research.
What is the chemical formula and molecular weight?
The formula is C5H9NO3 with a molecular weight of 131.13 g/mol.
How should trans-4-Hydroxy-L-proline be stored?
It should be stored at ambient temperature, protected from moisture and light.
What grade is available?
The product is supplied to a specification covering appearance (white to off-white crystalline powder), melting point (272-277 °C), pH (5.5-6.0), water content by KF (<0.1%) and identification by IR and Raman; specific grade and purity details can be provided upon request.
Can Molekula supply it in bulk?
Yes, bulk quantities are available—please contact our sales team for pricing and availability.
What documentation comes with the order?
Each order includes a Certificate of Analysis (CoA) and safety data sheet (SDS); additional documentation can be provided upon request.
Where can I buy trans-4-Hydroxy-L-proline?
Directly from Molekula, which lists trans-4-Hydroxy-L-proline in 25 g packs from £57.60 inc. VAT, with a certificate of analysis for every batch. Larger quantities are quoted on request. Molekula's offices: United Kingdom, France, Spain, Germany, Italy, United States and China.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.