Molekula
L-Leucine USP Grade
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
L-Leucine USP Grade is an essential branched-chain amino acid critical for protein synthesis, muscle repair, and metabolic regulation. Documented applications include nutritional and dietary supplements, flavoring of foods, biochemical research, and use as an ingredient in cosmetic formulations. It is widely used in pharmaceuticals, sports nutrition, and clinical nutrition formulations to support growth, recovery, and overall health. This USP-grade L-Leucine meets strict purity standards for human consumption, ensuring safety and efficacy in applications requiring high-quality amino acids. The product has a CAS number of 61-90-5, with a molecular formula of C6H13NO2 and a molecular weight of 131.17. It is stable at ambient storage conditions and carries no signal word, indicating no acute hazards. Molekula supplies L-Leucine USP Grade from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White crystal |
| Identification | IR: Conforms to reference |
| Total plate count | ≤1000CFU/g |
| pH | 5.5 - 7.0 |
| Loss on Drying | ≤0.2% |
| Chloride (Cl-) | ≤0.05% |
| Assay | 98.5% - 101.5% |
| Optical Rotation | +14.9° - +17.3° |
| Residue on Ignition | ≤0.4% |
| Individual impurity | ≤0.5% |
| Total Impurities | ≤2.0% |
| Bacterial endotoxins | ≤25EU/g |
| Iron (Fe) | ≤30ppm |
| E. Coli | Negative |
| Sulphates (SO4)(2-) | ≤0.03% |
| Mould & Yeast | ≤100CFU/g |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | White crystals |
| Melting Point | 293 °C |
| Density | 1.293 g/cm³ at 18 °C |
| Water Solubility | 21.5 g/L at 25 °C |
| Solubility (other solvents) | Soluble in water, acetic acid, dilute HCl, and alkaline hydroxides and carbonates |
| Vapour Pressure | 0.00000001 mmHg |
| pKa | pKa = 2.35 (at 13 °C) |
| log P (octanol/water) | -1.52 |
Source: PubChem CID 6106 (HSDB, DrugBank, Joint FAO/WHO Expert Committee on Food Additives (JECFA), Haz-Map)
Identification
| Property | Value |
|---|---|
| SKU | 90037535 |
| CAS Number | 61-90-5 |
| IUPAC Name | (2S)-2-amino-4-methylpentanoic acid |
| EC Number | 200-522-0 |
| Molecular Formula | C6H13NO2 |
| Molecular Weight | 131.17 |
| Exact Mass | 131.0946 |
| SMILES | CC(C)C[C@@H](C(=O)O)N |
| InChIKey | ROHFNLRQFUQHCH-YFKPBYRVSA-N |
| InChI | InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1 |
| PubChem CID | 6106 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29224949 |
| Tariff Code | 2922498590 |
Safety & GHS
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P403+233 Store in a well ventilated place. Keep container tightly closed
- P501 Dispose of contents/container to an approved waste disposal plant
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (2S)-2-amino-4-methylpentanoic acid
- (S)-2-Amino-4-methylpentanoic acid
- (S)-2-Amino-4-methylvaleric acid
- (S)-Leucine
- L-alpha-Aminoisocaproic acid
- L-leucine
- Leucin
- leucine
- LEUCINE, L-
- Leucinum
Frequently asked questions
What is L-Leucine USP Grade commonly used for?
L-Leucine USP Grade is primarily used in pharmaceuticals, nutritional supplements, and clinical nutrition as an essential branched-chain amino acid for protein synthesis and metabolic support.
What is the chemical formula and molecular weight of L-Leucine?
The chemical formula is **C6H13NO2**, and the molecular weight is **131.17 g/mol**.
Is L-Leucine USP Grade hazardous? What is the signal word?
No, L-Leucine USP Grade is **non-hazardous** and has **no signal word** as per safety classifications.
How should L-Leucine USP Grade be stored?
Store in a **cool, dry place** at **ambient temperature**, away from moisture and strong odors, in a tightly sealed container.
Does Molekula offer L-Leucine USP Grade in bulk quantities?
Yes, Molekula supplies L-Leucine USP Grade in **bulk quantities** (e.g., drums, totes) for industrial and commercial customers—contact us for custom packaging options.
What documentation is provided with an order of L-Leucine USP Grade?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **USP compliance documentation** to verify purity and grade.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.