Molekula
L-Leucine - Ph. Eur
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
L-Leucine is an essential branched-chain amino acid critical for protein synthesis, muscle repair, and metabolic regulation, widely used in sports nutrition, clinical formulations, and biochemical research. This pharmaceutical-grade L-Leucine (Ph. Eur.) meets European Pharmacopoeia standards, with a CAS number of 61-90-5, molecular formula C6H13NO2, and a molecular weight of 131.17. It requires no special storage conditions and carries no hazard classification. Molekula supplies L-Leucine from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to Off-white powder |
| Grade | EP |
| Specific rotation | +14.5° to +16.5° |
| Loss on Drying | ≤ 0.5% |
| Chloride (Cl-) | ≤ 200ppm |
| Assay | 98.5 - 101.0% |
| Sulphated Ash | ≤ 0.1% |
| Appearance of Solution | Clear colourless liquid |
| Heavy Metals (Pb) | ≤ 10ppm |
| Iron (Fe) | ≤ 10ppm |
| Sulphates (SO4)(2-) | ≤ 300ppm |
| Ninhydrin positive substances -Impurity A (@570nm)) | ≤ 0.08% |
| Ninhydrin positive substances - For each impurity | ≤ 0.02% |
| Ninhydrin positive substances - Total | ≤ 1.0% |
| Ninhydrin positive substances - Ammonium (@570nm)) | ≤ 0.02% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | White crystals |
| Melting Point | 293 °C |
| Density | 1.293 g/cm³ at 18 °C |
| Water Solubility | 21.5 g/L at 25 °C |
| Solubility (other solvents) | Soluble in water, acetic acid, dilute HCl, and alkaline hydroxides and carbonates |
| Vapour Pressure | 0.00000001 mmHg |
| pKa | pKa = 2.35 (at 13 °C) |
| log P (octanol/water) | -1.52 |
Source: PubChem CID 6106 (HSDB, DrugBank, Joint FAO/WHO Expert Committee on Food Additives (JECFA), Haz-Map)
Identification
| Property | Value |
|---|---|
| SKU | 90035135 |
| CAS Number | 61-90-5 |
| IUPAC Name | (2S)-2-amino-4-methylpentanoic acid |
| EC Number | 200-522-0 |
| Molecular Formula | C6H13NO2 |
| Molecular Weight | 131.17 |
| Exact Mass | 131.0946 |
| SMILES | CC(C)C[C@@H](C(=O)O)N |
| InChIKey | ROHFNLRQFUQHCH-YFKPBYRVSA-N |
| InChI | InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1 |
| PubChem CID | 6106 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29224949 |
| Tariff Code | 2922498590 |
Safety & GHS
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P403+233 Store in a well ventilated place. Keep container tightly closed
- P501 Dispose of contents/container to an approved waste disposal plant
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (2S)-2-amino-4-methylpentanoic acid
- (S)-2-Amino-4-methylpentanoic acid
- (S)-2-Amino-4-methylvaleric acid
- (S)-Leucine
- L-alpha-Aminoisocaproic acid
- L-leucine
- Leucin
- leucine
- LEUCINE, L-
- Leucinum
Frequently asked questions
What is L-Leucine (Ph. Eur) commonly used for?
L-Leucine (Ph. Eur) is primarily used as a dietary supplement for muscle growth and recovery, in clinical nutrition for patients with metabolic disorders, and as a building block in peptide synthesis.
What is the chemical formula and molecular weight of L-Leucine?
The chemical formula is **C6H13NO2**, and the molecular weight is **131.17 g/mol**.
How should L-Leucine (Ph. Eur) be stored?
Store at **ambient temperature** in a cool, dry place, away from direct sunlight and moisture.
What grade of L-Leucine does Molekula supply, and is it suitable for pharmaceutical use?
Molekula supplies **Ph. Eur.-grade L-Leucine**, which meets European Pharmacopoeia standards and is suitable for pharmaceutical, nutraceutical, and clinical applications.
Can Molekula supply L-Leucine in bulk quantities?
Yes, Molekula can supply L-Leucine in bulk, with flexible packaging options (e.g., drums, bags) to accommodate large orders.
What documentation comes with an order of L-Leucine (Ph. Eur)?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **Ph. Eur. compliance certificate** to ensure quality and regulatory adherence.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.