Molekula
L-Leucine - Ph. Eur
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
L-Leucine is an essential branched-chain amino acid critical for protein synthesis, muscle repair, and metabolic regulation, widely used in sports nutrition, clinical formulations, and biochemical research. This pharmaceutical-grade L-Leucine (Ph. Eur.) meets European Pharmacopoeia standards, with a CAS number of 61-90-5, molecular formula C6H13NO2, and a molecular weight of 131.17. It requires no special storage conditions and carries no hazard classification. Molekula supplies L-Leucine from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to Off-white powder |
| Grade | EP |
| Specific rotation | +14.5° to +16.5° |
| Loss on Drying | ≤ 0.5% |
| Chloride (Cl-) | ≤ 200ppm |
| Assay | 98.5 - 101.0% |
| Sulphated Ash | ≤ 0.1% |
| Appearance of Solution | Clear colourless liquid |
| Heavy Metals (Pb) | ≤ 10ppm |
| Iron (Fe) | ≤ 10ppm |
| Sulphates (SO4)(2-) | ≤ 300ppm |
| Ninhydrin positive substances -Impurity A (@570nm)) | ≤ 0.08% |
| Ninhydrin positive substances - For each impurity | ≤ 0.02% |
| Ninhydrin positive substances - Total | ≤ 1.0% |
| Ninhydrin positive substances - Ammonium (@570nm)) | ≤ 0.02% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | White crystals |
| Melting Point | 293 °C |
| Density | 1.293 g/cm³ at 18 °C |
| Water Solubility | 21.5 g/L at 25 °C |
| Solubility (other solvents) | Soluble in water, acetic acid, dilute HCl, and alkaline hydroxides and carbonates |
| Vapour Pressure | 0.00000001 mmHg |
| pKa | pKa = 2.35 (at 13 °C) |
| log P (octanol/water) | -1.52 |
Source: PubChem CID 6106 (HSDB, DrugBank, Joint FAO/WHO Expert Committee on Food Additives (JECFA), Haz-Map)
Identification
| Property | Value |
|---|---|
| SKU | 90035135 |
| CAS Number | 61-90-5 |
| IUPAC Name | (2S)-2-amino-4-methylpentanoic acid |
| EC Number | 200-522-0 |
| Molecular Formula | C6H13NO2 |
| Molecular Weight | 131.17 |
| Exact Mass | 131.0946 |
| SMILES | CC(C)C[C@@H](C(=O)O)N |
| InChIKey | ROHFNLRQFUQHCH-YFKPBYRVSA-N |
| InChI | InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1 |
| PubChem CID | 6106 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29224949 |
| Tariff Code | 2922498590 |
Safety & GHS
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P403+233 Store in a well ventilated place. Keep container tightly closed
- P501 Dispose of contents/container to an approved waste disposal plant
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Quality certificates
Molekula Group is certified to ISO 9001:2015 (quality) and ISO 14001:2015 (environmental management), audited by a UKAS-accredited body. Both certificates are valid to 17 May 2028.
Synonyms
- (2S)-2-amino-4-methylpentanoic acid
- (S)-2-Amino-4-methylpentanoic acid
- (S)-2-Amino-4-methylvaleric acid
- (S)-Leucine
- L-alpha-Aminoisocaproic acid
- L-leucine
- Leucin
- leucine
- LEUCINE, L-
- Leucinum
Frequently asked questions
What is L-Leucine (Ph. Eur) commonly used for?
L-Leucine (Ph. Eur) is primarily used as a dietary supplement for muscle growth and recovery, in clinical nutrition for patients with metabolic disorders, and as a building block in peptide synthesis.
What is the chemical formula and molecular weight of L-Leucine?
The chemical formula is **C6H13NO2**, and the molecular weight is **131.17 g/mol**.
How should L-Leucine (Ph. Eur) be stored?
Store at **ambient temperature** in a cool, dry place, away from direct sunlight and moisture.
What grade of L-Leucine does Molekula supply, and is it suitable for pharmaceutical use?
Molekula supplies **Ph. Eur.-grade L-Leucine**, which meets European Pharmacopoeia standards and is suitable for pharmaceutical, nutraceutical, and clinical applications.
Can Molekula supply L-Leucine in bulk quantities?
Yes, Molekula can supply L-Leucine in bulk, with flexible packaging options (e.g., drums, bags) to accommodate large orders.
What documentation comes with an order of L-Leucine (Ph. Eur)?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **Ph. Eur. compliance certificate** to ensure quality and regulatory adherence.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.