Molekula
trans-4-Hydroxy-L-proline (TF)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Certificate of Analysis with every batch
Trans-4-Hydroxy-L-proline (TF) is a naturally occurring amino acid derivative and a key building block in collagen synthesis, widely used in pharmaceuticals, cosmetics, and nutritional supplements for skin health and tissue repair. It appears as a white to off-white crystalline powder with no hazardous classification. Catalogue details: CAS 51-35-4, molecular formula C5H9NO3, molecular weight 131.13, stable at ambient storage conditions. Molekula supplies trans-4-Hydroxy-L-proline from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
This substance is available from Molekula on enquiry. Full specification, Safety Data Sheet and Certificate of Analysis documentation are provided with your quotation once our team confirms the grade and pack size you need.
Overview
- SKU
- 90031048
- CAS Number
- 51-35-4
- IUPAC Name
- (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
- EC Number
- 200-091-9
- Molecular Formula
- C5H9NO3
- Molecular Weight
- 131.13
- Exact Mass
- 131.0582
- SMILES
- C1[C@H](CN[C@@H]1C(=O)O)O
- InChIKey
- PMMYEEVYMWASQN-DMTCNVIQSA-N
- InChI
- InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1
- PubChem CID
- 5810
Synonyms
- (4R)-4-hydroxy-L-proline
- 4-Hydroxy-2-pyrrolidinecarboxylic acid
- hydroxy-L-proline
- hydroxyproline
- Hypro
- L-Hydroxyproline
- L-Proline, 4-hydroxy-, (4R)-
- trans-4-Hydroxy-L-proline
- trans-Hydroxyproline
- trans-L-Hydroxyproline
Literature values
Published physical properties of the substance, not batch specifications.
- Melting Point
- 274 - 275 °C
Source: PubChem CID 5810 (Human Metabolome Database (HMDB))
See the other grade of CAS 51-35-4 →
Frequently asked questions
What is trans-4-Hydroxy-L-proline (TF) used for?
trans-4-Hydroxy-L-proline is primarily used in biochemical research, pharmaceutical formulations, and as a building block for peptide synthesis due to its role in collagen stabilization.
What is the chemical formula and molecular weight of trans-4-Hydroxy-L-proline?
The chemical formula is **C₅H₉NO₃**, and the molecular weight is **131.13 g/mol**.
How should trans-4-Hydroxy-L-proline be stored?
Store at **ambient temperature** in a dry, well-ventilated area, away from moisture and strong oxidizing agents.
What grades or purities of trans-4-Hydroxy-L-proline does Molekula offer?
Molekula supplies **pharmaceutical-grade (USP/EP/BP)** and **analytical-grade** trans-4-Hydroxy-L-proline, with purity ≥98%.
Can Molekula supply trans-4-Hydroxy-L-proline in bulk quantities?
Yes, bulk quantities are available upon request, with minimum order quantities (MOQs) tailored to customer needs.
What documentation comes with an order of trans-4-Hydroxy-L-proline?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **batch-specific documentation** for traceability.
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Molekula has supplied fine chemicals and biochemicals since 2000 from ISO 9001:2015 and ISO 14001:2015 certified facilities. Every dispatched batch is logged with a batch number and matched to a Certificate of Analysis, and Safety Data Sheets are available in five languages.