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Molekula

Molekula

Tezacaftor VX661

SKU 90036926 CAS 1152311-62-0 C26H27F3N2O6 MW 520.50 Made to order Bulk quantities on request

Supplying 4,500+ customers in over 80 countries

ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need

Tezacaftor VX661 is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator used in the treatment of cystic fibrosis. It functions as a corrector to improve the function of defective CFTR proteins. Available with CAS number 1152311-62-0, its molecular formula is C26H27F3N2O6 and molecular weight is 520.50 g/mol. Stored at 2 to 8 °C, it carries a warning signal word. Molekula supplies Tezacaftor VX661 from research to bulk quantities with full documentation and ISO 9001:2015 traceability.

Expect a response within hours Speak to a chemist: +44 (0) 3302 000333

Example image for illustration only. Other packaging and pack sizes are available.

Pricing & pack sizes

Pack sizes & pricing

These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.

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  • 25 mg — £810.00 per pack ex VAT · £972.00 inc. VAT

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Specifications

Property Value
Appearance White to pale yellow powder
Purity 97% min

Storage & handling

Property Value
Storage Temperature 2 to 8 °C
Acidity Neutral

Literature values

Published physical properties of the substance, not batch specifications.

Property Value
Water Solubility Insoluble in water

Source: PubChem CID 46199646 (DrugBank)

Identification

Property Value
SKU 90036926
CAS Number 1152311-62-0
IUPAC Name 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide
Molecular Formula C26H27F3N2O6
Molecular Weight 520.50
Exact Mass 520.1821
SMILES CC(C)(CO)C1=CC2=CC(=C(C=C2N1C[C@H](CO)O)F)NC(=O)C3(CC3)C4=CC5=C(C=C4)OC(O5)(F)F
InChIKey MJUVRTYWUMPBTR-MRXNPFEDSA-N
InChI InChI=1S/C26H27F3N2O6/c1-24(2,13-33)22-8-14-7-18(17(27)10-19(14)31(22)11-16(34)12-32)30-23(35)25(5-6-25)15-3-4-20-21(9-15)37-26(28,29)36-20/h3-4,7-10,16,32-34H,5-6,11-13H2,1-2H3,(H,30,35)/t16-/m1/s1
PubChem CID 46199646
REACH Code Y113
HTS Code 29349990
Tariff Code 2934999090

Safety & GHS

Warning
  • GHS pictogram — Health Hazard Health Hazard GHS07

Hazard statements

  • H315 Causes skin irritation
  • H319 Causes serious eye irritation

Precautionary statements

  • P280 Wear protective gloves/protective clothing/eye protection/face protection
  • P302+352 IF ON SKIN: Wash with soap and water
  • P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
  • P332+313 IF skin irritation occurs: Get medical advice/attention
  • P337+313 If eye irritation persists get medical advice/attention

Documents

Safety Data Sheets (SDS)

Available in English, French, German, Italian, Spanish.

Certificate of Analysis (CoA) by batch

Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.

Synonyms

  • Alyftrek
  • CV6
  • Kaftrio
  • Symdeko
  • SYMKEVI COMPONENT TEZACAFTOR
  • Tezacaftor
  • Tezacaftor (USAN/INN)
  • tezacaftorum
  • TRIKAFTA COMPONENT TEZACAFTOR
  • VX 661

Frequently asked questions

What is Tezacaftor VX661 used for?

Tezacaftor VX661 is a CFTR modulator used in the treatment of cystic fibrosis, specifically targeting the F508del mutation in the CFTR protein.

What is the chemical formula and molecular weight of Tezacaftor VX661?

The formula is C26H27F3N2O6 with a molecular weight of 520.50 g/mol.

How should Tezacaftor VX661 be stored?

Store at 2 to 8 °C; do not freeze.

What grade is available for Tezacaftor VX661?

Available in research-grade purity; specific grades may vary based on order volume and application.

Can Molekula supply Tezacaftor VX661 in bulk?

Yes, Molekula can supply Tezacaftor VX661 in bulk quantities—please contact sales for pricing and availability.

What documentation comes with a Tezacaftor VX661 order?

Each order includes a Certificate of Analysis (CoA) and safety data sheet (SDS); additional documentation can be provided upon request.

Ready to order or need a custom pack?

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