Molekula
Caffeine - USP, BP, pH Eur
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Caffeine (58-08-2) is a natural xanthine alkaloid stimulant widely used in pharmaceuticals, beverages, and dietary supplements for its alertness-enhancing and metabolic-boosting properties. It meets USP, BP, and Ph. Eur. monograph standards, ensuring purity and consistency for regulatory compliance. The molecular formula is C8H10N4O2 with a molecular weight of 194.19. Store at ambient conditions. The product carries a warning signal word due to potential health risks at high doses. Molekula supplies Caffeine USP/BP/Ph. Eur. from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White crystalline powder |
| Assay/Purity | 98.5 - 101.0% |
| Melting Point | 235.0 - 237.5°C |
| Identification | Conforms to reference |
| Loss on Drying | ≤ 0.5% |
| Solubility | Sparingly soluble in water, freely soluble in boiling water, slightly soluble in ethanol (96%). It dissolves in concentrated solutions of alkali benzoates or salicylates. It sublimes readily |
| Acidity | ≤ 0.2ml of 0.01M NaOH |
| Appearance of Solution | Clear colourless |
| Total Impurities | ≤ 0.1% |
| Identification B | Retention time corresponds to USP standard |
| Sulphates (SO4)(2-) | ≤ 500ppm |
| Identification A | Spectrogram conforms to USP reference |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | White, prismatic crystals |
| Odour | Odorless |
| Melting Point | 236.2 °C |
| Boiling Point | 178 °C (sublimes) |
| Water Solubility | 21.6 g/L at 25 °C |
| Solubility (other solvents) | Soluble in pyridine |
| Vapour Pressure | 9.0 × 10⁻⁷ mmHg at 25 °C (Extrapolated) |
| pKa | pKa = 14 |
| log P (octanol/water) | -0.07 |
Source: PubChem CID 2519 (HSDB, ICSC, DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 90037429 |
| CAS Number | 58-08-2 |
| IUPAC Name | 1,3,7-trimethylpurine-2,6-dione |
| EC Number | 200-362-1 |
| Molecular Formula | C8H10N4O2 |
| Molecular Weight | 194.19 |
| Exact Mass | 194.0804 |
| SMILES | CN1C=NC2=C1C(=O)N(C(=O)N2C)C |
| InChIKey | RYYVLZVUVIJVGH-UHFFFAOYSA-N |
| InChI | InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3 |
| PubChem CID | 2519 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29393000 |
| Tariff Code | 293930000000 |
Safety & GHS
-
Health Hazard
GHS07
Hazard statements
- H302 Harmful if swallowed
- H332 Harmful if inhaled
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 1,3,7-Trimethylxanthine
- Cafeina
- Caffein
- caffeine
- Cafipel
- Guaranine
- Koffein
- Methyltheobromine
- Thein
- Theine
Frequently asked questions
What is caffeine USP/BP/pH Eur used for?
Caffeine USP/BP/pH Eur is primarily used in pharmaceuticals (e.g., stimulants, analgesics), dietary supplements, and as a food additive (e.g., energy drinks, sodas) to enhance alertness and concentration.
What is the chemical formula and molecular weight of caffeine?
The chemical formula is **C₈H₁₀N₄O₂**, and the molecular weight is **194.19 g/mol**.
How should caffeine USP/BP/pH Eur be stored?
Store in a cool, dry place at ambient temperature, away from moisture and direct sunlight. Ensure containers are tightly sealed.
What grades of caffeine does Molekula supply?
Molekula supplies caffeine in **USP (United States Pharmacopeia), BP (British Pharmacopeia), and Ph. Eur. (European Pharmacopeia)** grades, meeting strict pharmaceutical and regulatory standards.
Can Molekula supply caffeine USP/BP/pH Eur in bulk quantities?
Yes, Molekula can supply caffeine in bulk, with quantities tailored to meet your production or formulation needs—please contact us for pricing and logistics details.
What documentation comes with an order of caffeine USP/BP/pH Eur?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **batch-specific documentation** to verify compliance with USP, BP, and Ph. Eur. standards.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.