Molekula
S-(-)-Nicotine
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
S-(-)-Nicotine is a chiral alkaloid derived from tobacco, primarily used in research, pharmaceutical development, and nicotine replacement therapies. It is the biologically active enantiomer of nicotine, influencing the nervous system and exhibiting stimulant properties. It is also used as a restricted-use insecticide on greenhouse ornamental plants and as the active ingredient in nicotine patches and other medicinal products. CAS 54-11-5, molecular formula C10H14N2, molecular weight 162.23 g/mol. Store at ambient temperature. Signal word: Danger. Molekula supplies S-(-)-Nicotine from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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25 g — £38.70 per pack ex VAT · £46.44 inc. VAT
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100 g — £93.50 per pack ex VAT · £112.20 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Colourless or brownish viscous liquid |
| Water | ≤0.5% |
| Specific rotation | -140 to -152 |
| Heavy metals | ≤10ppm |
| Assay | ≥98.0% |
| Sulphated Ash | ≤0.1% |
| Ethanol | ≤0.5% |
| Hexane | ≤0.03% |
| Nicotine-trans-N-Oxide | ≤0.2% |
| Nicotine-cis-N-Oxide | ≤0.2% |
| Myosmine | ≤0.5% |
| Nornicotine | ≤0.5% |
| Anabasine | ≤0.3% |
| Anatabine | ≤0.3% |
| Total Nicotine-N-Oxides | ≤0.3% |
| Total Impurities (spec. and unspec.) | ≤1% |
| Any Unidentified Impurity | ≤0.1% |
| beta-nicotyrine | ≤0.2% |
| Continine | ≤0.2% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Flash Point | 101 °C |
| Transport Class | 6.1 |
| Packing Group | II |
| Acidity | Base |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Colorless to pale yellow, oily liquid |
| Odour | Fish-like odor when warm |
| Melting Point | -79 °C |
| Boiling Point | 247 °C |
| Density | 1.01 (relative, water = 1) |
| Water Solubility | 1000 g/L at 25 °C (miscible) |
| Vapour Pressure | 0.006 kPa at 20 °C |
| Refractive Index | 1.5282 |
| pKa | pKa = 8.5 |
| log P (octanol/water) | 1.17 |
Source: PubChem CID 89594 (HSDB, DrugBank, ICSC)
Identification
| Property | Value |
|---|---|
| SKU | 25698234 |
| CAS Number | 54-11-5 |
| IUPAC Name | 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine |
| EC Number | 200-193-3 |
| Molecular Formula | C10H14N2 |
| Molecular Weight | 162.23 |
| Exact Mass | 162.1157 |
| SMILES | CN1CCC[C@H]1C2=CN=CC=C2 |
| InChIKey | SNICXCGAKADSCV-JTQLQIEISA-N |
| InChI | InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1 |
| PubChem CID | 89594 |
| UN Number | UN1654 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29397900 |
| Tariff Code | 2939791000 |
Safety & GHS
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Corrosive
GHS05
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Toxic
GHS06
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Hazardous to the Environment
GHS09
Hazard statements
- H300 +H310 + H330 Fatal if swallowed, in contact with skin or if inhaled
- H315 Causes skin irritation
- H318 Causes serious eye damage
- H411 Toxic to aquatic life with long lasting effects
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P501 Dispose of contents/container to an approved waste disposal plant
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Russian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (S)-3-(1-methylpyrrolidin-2-yl)pyridine
- 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
- Fumetobac
- Habitrol
- L-Nicotine
- Nicocide
- Nicoderm
- Nicoderm Cq
- nicotine
- Nicotrol
Frequently asked questions
What is S-(-)-Nicotine primarily used for?
S-(-)-Nicotine is primarily used in research for studying nicotine’s pharmacological effects, as a standard in analytical chemistry, and as a precursor for synthesizing nicotine-based compounds.
What is the chemical formula and molecular weight of S-(-)-Nicotine?
The chemical formula is **C10H14N2** and the molecular weight is **162.23 g/mol**.
How should S-(-)-Nicotine be stored?
Store S-(-)-Nicotine at **ambient temperature** in a tightly sealed container, away from light and moisture.
What purity grades of S-(-)-Nicotine does Molekula offer?
Molekula supplies S-(-)-Nicotine in **analytical and research-grade purity**, typically ≥98% by HPLC.
Can Molekula supply S-(-)-Nicotine in bulk quantities?
Yes, Molekula can provide S-(-)-Nicotine in bulk, with quantities and packaging tailored to your research or production needs.
What documentation comes with an order of S-(-)-Nicotine?
Each order includes a **Certificate of Analysis (CoA)**, Material Safety Data Sheet (MSDS), and a product specification sheet detailing purity, identity, and storage instructions.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.