Molekula
Vonoprazan fumarate
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Vonoprazan fumarate is a proton pump inhibitor used in the treatment of gastric acid-related disorders. It is available as a fumarate salt with a molecular formula of C17H16FN3O2S·C4H4O4 and a molecular weight of 461.46 g/mol. It should be stored at 2 to 8 °C. The substance carries a warning signal word. Molekula supplies Vonoprazan fumarate from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White or off-white crystal or crystalline powder |
| Melting Point | 193°C-197°C |
| Heavy metals | ≤20ppm |
| Fumaric acid | 23.9-26.5% |
| Acetonitrile | ≤0.041% |
| Loss on Drying | ≤0.40% |
| Solubility | Slightly soluble in methanol or water and practically insoluble in isopropanol or acetonitrile |
| Assay | 98.0-102.0% (DRIED BASIS) |
| Ethanol | ≤0.5% |
| Dichloromethane | ≤0.06% |
| Methanol | ≤0.3% |
| Residue on Ignition | ≤0.1% |
| Ethyl acetate | ≤0.5% |
| Pyridine | ≤0.02% |
| HPLC | The retention time of the major peak of the sample solution corresponds to that of the standard solution as obtained in the assay. |
| Organic impurities | Single impurity: ≤0.15%. Total impurities: ≤1.0% |
| Benzene | ≤0.0002% |
| Acetic acid | ≤0.5% |
| Identification (IR) | The infrared absorption spectrum of the sample shall be consistent with that of the reference substance |
| N,N-dimethylacetamide | ≤0.109% |
| Tetrahydrofuran | ≤0.072% |
| Fluoride (F-) | 3.7%-4.3% |
| N,N-diisopropylethylamine | ≤0.1% |
| Methylamine | ≤0.1% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Flash Point | 79 °C |
| Transport Class | 9 |
| Packing Group | III |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 90032177 |
| CAS Number | 1260141-27-2 |
| IUPAC Name | (E)-but-2-enedioic acid;1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine |
| Molecular Formula | C17H16FN3O2S·C4H4O4 |
| Molecular Weight | 461.46 |
| Exact Mass | 461.1057 |
| SMILES | CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=C/C(=O)O)\C(=O)O |
| InChIKey | ROGSHYHKHPCCJW-WLHGVMLRSA-N |
| InChI | InChI=1S/C17H16FN3O2S.C4H4O4/c1-19-10-13-9-17(15-6-2-3-7-16(15)18)21(12-13)24(22,23)14-5-4-8-20-11-14;5-3(6)1-2-4(7)8/h2-9,11-12,19H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+ |
| PubChem CID | 45375887 |
| UN Number | UN3077 |
| REACH Code | Y110 |
| Tariff Code | 2933399990 |
Safety & GHS
-
Health Hazard
GHS07
-
Serious Health Hazard
GHS08
-
Hazardous to the Environment
GHS09
Hazard statements
- H302 + H312 + H332 Harmful if swallowed, in contact with skin or if inhaled
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H351 Suspected of causing cancer
- H373 May cause damage to organs through prolonged or repeated exposure
- H411 Toxic to aquatic life with long lasting effects
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- TAK 438
- TAK-438 monofumarate
- takecab
- Vonoprazan Fumarate (TAK-438)
- Vonoprazan fumurate
- Vonoprazan monofumarate
- Vonoprazan monofumurate
- VOQUEZNA
- Voquezna (TN)
- Voranomazin
Frequently asked questions
What is vonoprazan fumarate used for?
Vonoprazan fumarate is primarily used as a potassium-competitive acid blocker (P-CAB) for the treatment of conditions like gastroesophageal reflux disease (GERD) and Helicobacter pylori eradication.
What is the chemical formula and molecular weight of vonoprazan fumarate?
The chemical formula is **C17H16FN3O2S·C4H4O4**, and the molecular weight is **461.46 g/mol**.
How should vonoprazan fumarate be stored?
Store vonoprazan fumarate at **2 to 8°C** to maintain stability and potency.
What grade or purity is available for vonoprazan fumarate?
Molekula supplies vonoprazan fumarate in **pharmaceutical-grade purity** suitable for research and development applications.
Can Molekula supply vonoprazan fumarate in bulk quantities?
Yes, Molekula can provide vonoprazan fumarate in bulk, with quantities tailored to your research or production needs.
What documentation comes with an order of vonoprazan fumarate?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and batch-specific documentation for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.