Molekula
Tezacaftor VX661
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Tezacaftor VX661 is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator used in the treatment of cystic fibrosis. It functions as a corrector to improve the function of defective CFTR proteins. Available with CAS number 1152311-62-0, its molecular formula is C26H27F3N2O6 and molecular weight is 520.50 g/mol. Stored at 2 to 8 °C, it carries a warning signal word.
Molekula supplies Tezacaftor VX661 at 97% min purity in 25 mg packs, from £972.00 inc. VAT. It is made or sourced to order. Every batch ships with a certificate of analysis, and safety data sheets are available in 5 languages. Larger quantities, up to multi-tonne, are quoted on request.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
On backorder — expected to ship by 5 December 2026
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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25 mg — £810.00 per pack ex VAT · £972.00 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to pale yellow powder |
| Purity | 97% min |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Water Solubility | Insoluble in water |
Source: PubChem CID 46199646 (DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 90036926 |
| CAS Number | 1152311-62-0 |
| IUPAC Name | 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide |
| Molecular Formula | C26H27F3N2O6 |
| Molecular Weight | 520.50 |
| Exact Mass | 520.1821 |
| SMILES | CC(C)(CO)C1=CC2=CC(=C(C=C2N1C[C@H](CO)O)F)NC(=O)C3(CC3)C4=CC5=C(C=C4)OC(O5)(F)F |
| InChIKey | MJUVRTYWUMPBTR-MRXNPFEDSA-N |
| InChI | InChI=1S/C26H27F3N2O6/c1-24(2,13-33)22-8-14-7-18(17(27)10-19(14)31(22)11-16(34)12-32)30-23(35)25(5-6-25)15-3-4-20-21(9-15)37-26(28,29)36-20/h3-4,7-10,16,32-34H,5-6,11-13H2,1-2H3,(H,30,35)/t16-/m1/s1 |
| PubChem CID | 46199646 |
| REACH Code | Y113 |
| HTS Code | 29349990 |
| Tariff Code | 2934999090 |
Safety & GHS
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Health Hazard
GHS07
Hazard statements
- H315 Causes skin irritation
- H319 Causes serious eye irritation
Precautionary statements
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P332+313 IF skin irritation occurs: Get medical advice/attention
- P337+313 If eye irritation persists get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Quality certificates
Molekula Group is certified to ISO 9001:2015 (quality) and ISO 14001:2015 (environmental management), audited by a UKAS-accredited body. Both certificates are valid to 17 May 2028.
Synonyms
- Alyftrek
- CV6
- Kaftrio
- Symdeko
- SYMKEVI COMPONENT TEZACAFTOR
- Tezacaftor
- Tezacaftor (USAN/INN)
- tezacaftorum
- TRIKAFTA COMPONENT TEZACAFTOR
- VX 661
Frequently asked questions
What is Tezacaftor VX661 used for?
Tezacaftor VX661 is a CFTR modulator used in the treatment of cystic fibrosis, specifically targeting the F508del mutation in the CFTR protein.
What is the chemical formula and molecular weight of Tezacaftor VX661?
The formula is C26H27F3N2O6 with a molecular weight of 520.50 g/mol.
How should Tezacaftor VX661 be stored?
Store at 2 to 8 °C; do not freeze.
What grade is available for Tezacaftor VX661?
Tezacaftor VX661 is supplied as a white to pale yellow powder with a purity of 97% min.
Can Molekula supply Tezacaftor VX661 in bulk?
Yes, Molekula can supply Tezacaftor VX661 in bulk quantities—please contact sales for pricing and availability.
What documentation comes with a Tezacaftor VX661 order?
Each order includes a Certificate of Analysis (CoA) and safety data sheet (SDS); additional documentation can be provided upon request.
Where can I buy Tezacaftor VX661?
Directly from Molekula, which lists Tezacaftor VX661 in 25 mg packs from £972.00 inc. VAT, with a certificate of analysis for every batch. Larger quantities are quoted on request. Molekula's offices: United Kingdom, France, Spain, Germany, Italy, United States and China.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.