Molekula
Leflunomide
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Leflunomide is an immunomodulatory drug used primarily in the treatment of rheumatoid arthritis and other autoimmune conditions. It functions by inhibiting dihydroorotate dehydrogenase, thereby suppressing immune cell proliferation. Available with CAS number 75706-12-6, molecular formula C12H9F3N2O2, and molecular weight 270.21 g/mol, it must be stored at 2 to 8 °C. The substance is classified as Danger. Molekula supplies Leflunomide from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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100 mg — £62.10 per pack ex VAT · £74.52 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | white powder |
| Storage Temperature | +20 ° C |
| Assay | 99% min |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Transport Class | 6.1 |
| Packing Group | III |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Melting Point | 166.5 °C |
| Vapour Pressure | 1.25 × 10⁻⁶ mmHg at 25 °C (Estimated) |
| log P (octanol/water) | 2.43 |
Source: PubChem CID 3899 (HSDB)
Identification
| Property | Value |
|---|---|
| SKU | 77117657 |
| CAS Number | 75706-12-6 |
| IUPAC Name | 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide |
| Molecular Formula | C12H9F3N2O2 |
| Molecular Weight | 270.21 |
| Exact Mass | 270.0616 |
| SMILES | CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F |
| InChIKey | VHOGYURTWQBHIL-UHFFFAOYSA-N |
| InChI | InChI=1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18) |
| PubChem CID | 3899 |
| UN Number | UN2811 |
| REACH Code | Y110 |
| HTS Code | 2934.99.3000 |
| Tariff Code | 2934999090 |
Safety & GHS
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Toxic
GHS06
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Health Hazard
GHS07
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Serious Health Hazard
GHS08
Hazard statements
- H301 Toxic if swallowed
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
- H360 May damage fertility or the unborn child
- H362 May cause harm to breast-fed children
- H372 Causes damage to organs through prolonged or repeated exposure
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P263 Avoid contact during pregnancy/while nursing
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
- 5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide
- Arava
- Leflunomida
- leflunomide medac
- Leflunomide teva
- Leflunomide winthrop
- Leflunomidum
- Repso
- SULOL
Frequently asked questions
What is leflunomide used for?
Leflunomide is primarily used in the treatment of autoimmune diseases such as rheumatoid arthritis, where it acts as an immunomodulator by inhibiting dihydroorotate dehydrogenase.
What is the chemical formula and molecular weight of leflunomide?
The chemical formula of leflunomide is C12H9F3N2O2, and its molecular weight is 270.21 g/mol.
How should leflunomide be stored?
Leflunomide should be stored at temperatures between 2 and 8 °C, protected from light and moisture.
What grade of leflunomide does Molekula supply?
Molekula supplies leflunomide in research grade, suitable for laboratory use and non-pharmaceutical applications.
Can Molekula supply leflunomide in bulk quantities?
Yes, Molekula can supply leflunomide in bulk quantities—please contact our sales team for pricing and availability.
What documentation comes with a leflunomide order?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS); additional documentation can be provided upon request.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.