Molekula
L-Proline
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
L-Proline is a non-essential amino acid used in peptide synthesis, pharmaceuticals, and as a catalyst in organic reactions. It also serves as a starting material for captopril and enalapril, a component of microbiological culture media and parenteral nutrition formulations, and a food flavoring and nutritional supplement ingredient. It is a white crystalline powder with a molecular formula of C5H9NO2, a molecular weight of 115.13 g/mol, and a CAS number of 147-85-3. Stable at ambient temperatures, it requires no special storage conditions. Molekula supplies L-Proline from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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100 g — $58.70 per pack
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1 kg — $216.10 per pack
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White powder |
| Specific rotation | -84.5° to -86.0° |
| Heavy metals | ≤ 15ppm |
| Identification | Conforms to reference |
| pH | 5.9 - 6.9 |
| Loss on Drying | ≤ 0.3% |
| Chloride (Cl-) | ≤ 0.050% |
| Assay | 99.0 - 101.0% |
| Residue on Ignition | ≤ 0.10% |
| Iron (Fe) | ≤ 30ppm |
| Arsenic (As) | ≤ 1ppm |
| Ammonium (NH4+) | ≤ 0.02% |
| Sulphates (SO4)(2-) | ≤ 0.050% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | White crystals or crystalline powder |
| Odour | Odorless |
| Melting Point | 220-222 °C, decomposes |
| Solubility (other solvents) | Very soluble in water, alcohol; insoluble in ether |
| log P (octanol/water) | -2.54 |
Source: PubChem CID 145742 (HSDB)
Identification
| Property | Value |
|---|---|
| SKU | 13422892 |
| CAS Number | 147-85-3 |
| IUPAC Name | (2S)-pyrrolidine-2-carboxylic acid |
| EC Number | 205-702-2 |
| Molecular Formula | C5H9NO2 |
| Molecular Weight | 115.13 |
| Exact Mass | 115.0633 |
| SMILES | C1C[C@H](NC1)C(=O)O |
| InChIKey | ONIBWKKTOPOVIA-BYPYZUCNSA-N |
| InChI | InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1 |
| PubChem CID | 145742 |
| REACH Code | Y113 |
| TSCA Listed | Yes |
| HTS Code | 29339980 |
| Tariff Code | 2933998090 |
Safety & GHS
Precautionary statements
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (-)-(S)-Proline
- (2S)-pyrrolidine-2-carboxylic acid
- (S)-2-Pyrrolidinecarboxylic acid
- (S)-Pyrrolidine-2-carboxylic acid
- 2-pyrrolidinecarboxylic acid
- L-alpha-Pyrrolidinecarboxylic acid
- L-Prolin
- prolina
- proline
- Prolinum
Frequently asked questions
What is L-Proline used for?
L-Proline is commonly used as a building block in peptide synthesis and as a catalyst in asymmetric synthesis reactions.
What is the chemical formula and molecular weight of L-Proline?
The formula is C5H9NO2 and the molecular weight is 115.13 g/mol.
How should L-Proline be stored?
L-Proline should be stored at ambient temperature, protected from moisture and light.
What grade of L-Proline does Molekula supply?
Molekula supplies L-Proline in reagent grade, suitable for laboratory and research use.
Can Molekula supply L-Proline in bulk?
Yes, Molekula can supply L-Proline in bulk quantities—please contact our sales team for pricing and availability.
What documentation comes with an order of L-Proline?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS) with the shipment.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.