Molekula
L-Proline USP Grade (TRQ)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
L-Proline USP Grade (TRQ) is a non-essential amino acid with a pyrrolidine ring structure, widely used as a nutritional supplement, in pharmaceutical formulations, and as a chiral catalyst in organic synthesis. It supports collagen production, stabilizes proteins, and enhances flavor in food applications. This USP-grade L-Proline has a CAS number of 147-85-3, molecular formula C5H9NO2, and a molecular weight of 115.13. It requires no special storage conditions and carries no signal word for hazard classification. Molekula supplies L-Proline USP Grade from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | white to off white crystalline powder |
| Water | ≤0.4% |
| Heavy metals | ≤10ppm |
| Identification | The spectrum of the test sample corresponds to the spectrum of the reference standard |
| Loss on Drying | ≤0.5% |
| Assay | 98-102% (dried basis) |
| Optical Rotation | -86.3° - 84.3° |
| Residue on Ignition | ≤0.2% |
| Individual impurity | ≤0.2% |
| Total Impurities | ≤1.0% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | White crystals or crystalline powder |
| Odour | Odorless |
| Melting Point | 220-222 °C, decomposes |
| Solubility (other solvents) | Very soluble in water, alcohol; insoluble in ether |
| log P (octanol/water) | -2.54 |
Source: PubChem CID 145742 (HSDB)
Identification
| Property | Value |
|---|---|
| SKU | 90033802 |
| CAS Number | 147-85-3 |
| IUPAC Name | (2S)-pyrrolidine-2-carboxylic acid |
| EC Number | 205-702-2 |
| Molecular Formula | C5H9NO2 |
| Molecular Weight | 115.13 |
| Exact Mass | 115.0633 |
| SMILES | C1C[C@H](NC1)C(=O)O |
| InChIKey | ONIBWKKTOPOVIA-BYPYZUCNSA-N |
| InChI | InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1 |
| PubChem CID | 145742 |
| REACH Code | Y113 |
| TSCA Listed | Yes |
| HTS Code | 29339980 |
| Tariff Code | 2933998090 |
Safety & GHS
Precautionary statements
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Quality certificates
Molekula Group is certified to ISO 9001:2015 (quality) and ISO 14001:2015 (environmental management), audited by a UKAS-accredited body. Both certificates are valid to 17 May 2028.
Synonyms
- (-)-(S)-Proline
- (2S)-pyrrolidine-2-carboxylic acid
- (S)-2-Pyrrolidinecarboxylic acid
- (S)-Pyrrolidine-2-carboxylic acid
- 2-pyrrolidinecarboxylic acid
- L-Prolin
- L-proline
- prolina
- proline
- Prolinum
Frequently asked questions
What is L-Proline USP Grade (TRQ) commonly used for?
L-Proline USP Grade (TRQ) is primarily used in pharmaceuticals, nutritional supplements, and as a building block in peptide synthesis due to its high purity and compliance with USP standards.
What is the chemical formula and molecular weight of L-Proline USP Grade (TRQ)?
The chemical formula is C5H9NO2 and the molecular weight is 115.13 g/mol.
How should L-Proline USP Grade (TRQ) be stored?
Store at ambient temperature in a dry, well-ventilated area, away from moisture and strong oxidizing agents.
What grade of L-Proline does Molekula supply, and is USP Grade (TRQ) available?
Molekula supplies USP Grade (TRQ) L-Proline, meeting strict pharmaceutical and regulatory standards for traceability and quality.
Can Molekula supply L-Proline USP Grade (TRQ) in bulk quantities?
Yes, Molekula can supply L-Proline USP Grade (TRQ) in bulk, with flexible packaging options to meet your production needs.
What documentation comes with an order of L-Proline USP Grade (TRQ)?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and USP compliance documentation for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.