Molekula
L-Proline USP Grade (TRQ)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
L-Proline USP Grade (TRQ) is a non-essential amino acid with a pyrrolidine ring structure, widely used as a nutritional supplement, in pharmaceutical formulations, and as a chiral catalyst in organic synthesis. It supports collagen production, stabilizes proteins, and enhances flavor in food applications. This USP-grade L-Proline has a CAS number of 147-85-3, molecular formula C5H9NO2, and a molecular weight of 115.13. It requires no special storage conditions and carries no signal word for hazard classification. Molekula supplies L-Proline USP Grade from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | white to off white crystalline powder |
| Water | ≤0.4% |
| Heavy metals | ≤10ppm |
| Identification | The spectrum of the test sample corresponds to the spectrum of the reference standard |
| Loss on Drying | ≤0.5% |
| Assay | 98-102% (dried basis) |
| Optical Rotation | -86.3° - 84.3° |
| Residue on Ignition | ≤0.2% |
| Individual impurity | ≤0.2% |
| Total Impurities | ≤1.0% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | White crystals or crystalline powder |
| Odour | Odorless |
| Melting Point | 220-222 °C, decomposes |
| Solubility (other solvents) | Very soluble in water, alcohol; insoluble in ether |
| log P (octanol/water) | -2.54 |
Source: PubChem CID 145742 (HSDB)
Identification
| Property | Value |
|---|---|
| SKU | 90033802 |
| CAS Number | 147-85-3 |
| IUPAC Name | (2S)-pyrrolidine-2-carboxylic acid |
| EC Number | 205-702-2 |
| Molecular Formula | C5H9NO2 |
| Molecular Weight | 115.13 |
| Exact Mass | 115.0633 |
| SMILES | C1C[C@H](NC1)C(=O)O |
| InChIKey | ONIBWKKTOPOVIA-BYPYZUCNSA-N |
| InChI | InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1 |
| PubChem CID | 145742 |
| REACH Code | Y113 |
| TSCA Listed | Yes |
| HTS Code | 29339980 |
| Tariff Code | 2933998090 |
Safety & GHS
Precautionary statements
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (-)-(S)-Proline
- (2S)-pyrrolidine-2-carboxylic acid
- (S)-2-Pyrrolidinecarboxylic acid
- (S)-Pyrrolidine-2-carboxylic acid
- 2-pyrrolidinecarboxylic acid
- L-Prolin
- L-proline
- prolina
- proline
- Prolinum
Frequently asked questions
What is L-Proline USP Grade (TRQ) commonly used for?
L-Proline USP Grade (TRQ) is primarily used in pharmaceuticals, nutritional supplements, and as a building block in peptide synthesis due to its high purity and compliance with USP standards.
What is the chemical formula and molecular weight of L-Proline USP Grade (TRQ)?
The chemical formula is **C5H9NO2** and the molecular weight is **115.13 g/mol**.
How should L-Proline USP Grade (TRQ) be stored?
Store at **ambient temperature** in a dry, well-ventilated area, away from moisture and strong oxidizing agents.
What grade of L-Proline does Molekula supply, and is USP Grade (TRQ) available?
Molekula supplies **USP Grade (TRQ) L-Proline**, meeting strict pharmaceutical and regulatory standards for traceability and quality.
Can Molekula supply L-Proline USP Grade (TRQ) in bulk quantities?
Yes, Molekula can supply L-Proline USP Grade (TRQ) in bulk, with flexible packaging options to meet your production needs.
What documentation comes with an order of L-Proline USP Grade (TRQ)?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **USP compliance documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.