Molekula
L-Proline
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
L-Proline is a non-essential amino acid used in peptide synthesis, pharmaceuticals, and as a catalyst in organic reactions. It also serves as a starting material for captopril and enalapril, a component of microbiological culture media and parenteral nutrition formulations, and a food flavoring and nutritional supplement ingredient. It is a white crystalline powder with a molecular formula of C5H9NO2, a molecular weight of 115.13 g/mol, and a CAS number of 147-85-3. Stable at ambient temperatures, it requires no special storage conditions.
Molekula supplies L-Proline at 99.0 - 101.0% purity in 100 g and 1 kg packs, from £37.08 inc. VAT. It is in stock for same-day dispatch. Every batch ships with a certificate of analysis, and safety data sheets are available in 5 languages. Larger quantities, up to multi-tonne, are quoted on request.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
In stock — same-day dispatch
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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100 g — £30.90 per pack ex VAT · £37.08 inc. VAT
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1 kg — £113.80 per pack ex VAT · £136.56 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White powder |
| Specific rotation | -84.5° to -86.0° |
| Heavy metals | ≤ 15ppm |
| Identification | Conforms to reference |
| pH | 5.9 - 6.9 |
| Loss on Drying | ≤ 0.3% |
| Chloride (Cl-) | ≤ 0.050% |
| Assay | 99.0 - 101.0% |
| Residue on Ignition | ≤ 0.10% |
| Iron (Fe) | ≤ 30ppm |
| Arsenic (As) | ≤ 1ppm |
| Ammonium (NH4+) | ≤ 0.02% |
| Sulphates (SO4)(2-) | ≤ 0.050% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | White crystals or crystalline powder |
| Odour | Odorless |
| Melting Point | 220-222 °C, decomposes |
| Solubility (other solvents) | Very soluble in water, alcohol; insoluble in ether |
| log P (octanol/water) | -2.54 |
Source: PubChem CID 145742 (HSDB)
Identification
| Property | Value |
|---|---|
| SKU | 13422892 |
| CAS Number | 147-85-3 |
| IUPAC Name | (2S)-pyrrolidine-2-carboxylic acid |
| EC Number | 205-702-2 |
| Molecular Formula | C5H9NO2 |
| Molecular Weight | 115.13 |
| Exact Mass | 115.0633 |
| SMILES | C1C[C@H](NC1)C(=O)O |
| InChIKey | ONIBWKKTOPOVIA-BYPYZUCNSA-N |
| InChI | InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1 |
| PubChem CID | 145742 |
| REACH Code | Y113 |
| TSCA Listed | Yes |
| HTS Code | 29339980 |
| Tariff Code | 2933998090 |
Safety & GHS
Precautionary statements
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Quality certificates
Molekula Group is certified to ISO 9001:2015 (quality) and ISO 14001:2015 (environmental management), audited by a UKAS-accredited body. Both certificates are valid to 17 May 2028.
Synonyms
- (-)-(S)-Proline
- (2S)-pyrrolidine-2-carboxylic acid
- (S)-2-Pyrrolidinecarboxylic acid
- (S)-Pyrrolidine-2-carboxylic acid
- 2-pyrrolidinecarboxylic acid
- L-alpha-Pyrrolidinecarboxylic acid
- L-Prolin
- prolina
- proline
- Prolinum
Frequently asked questions
What is L-Proline used for?
L-Proline is commonly used as a building block in peptide synthesis and as a catalyst in asymmetric synthesis reactions.
What is the chemical formula and molecular weight of L-Proline?
The formula is C5H9NO2 and the molecular weight is 115.13 g/mol.
How should L-Proline be stored?
L-Proline should be stored at ambient temperature, protected from moisture and light.
What grade of L-Proline does Molekula supply?
Molekula supplies L-Proline with an assay of 99.0–101.0%, with specified limits for impurities including heavy metals, iron, arsenic, chloride, sulphates and ammonium.
Can Molekula supply L-Proline in bulk?
Yes, Molekula can supply L-Proline in bulk quantities—please contact our sales team for pricing and availability.
What documentation comes with an order of L-Proline?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS) with the shipment.
Where can I buy L-Proline?
Directly from Molekula, which lists L-Proline in 100 g and 1 kg packs from £37.08 inc. VAT, with a certificate of analysis for every batch. Larger quantities are quoted on request. Molekula's offices: United Kingdom, France, Spain, Germany, Italy, United States and China.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.