Molekula
Trioctylphosphine oxide
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Trioctylphosphine oxide (TOPO) is a phosphorus-based organophosphine oxide widely used as a ligand in semiconductor manufacturing, particularly in the synthesis of III-V and II-VI compounds via organometallic vapor phase epitaxy (OMVPE). It acts as a stabilizing agent, solvent, and phase-transfer catalyst in chemical processes. This clear, viscous liquid has a CAS number of 78-50-2, with the molecular formula [CH3(CH2)7]3PO and a molecular weight of 386.63. It should be stored at ambient conditions but handled with caution, as it carries a "Danger" signal word. Molekula supplies trioctylphosphine oxide from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
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500 g — £337.80 per pack ex VAT · £405.36 inc. VAT
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Specifications
| Property | Value |
|---|---|
| Appearance | White solid |
| Density | 0.86 - 0.92g/ml |
| Melting Point | 47 - 52°C |
| Content | ≥90.0% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Flash Point | 230 °C |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Melting Point | 52 °C |
Source: PubChem CID 65577 (PAC Chemical Database)
Identification
| Property | Value |
|---|---|
| SKU | 90030274 |
| CAS Number | 78-50-2 |
| IUPAC Name | 1-dioctylphosphoryloctane |
| EC Number | 201-121-3 |
| Molecular Formula | [CH3(CH2)7]3PO |
| Molecular Weight | 386.63 |
| Exact Mass | 386.3678 |
| SMILES | CCCCCCCCP(=O)(CCCCCCCC)CCCCCCCC |
| InChIKey | ZMBHCYHQLYEYDV-UHFFFAOYSA-N |
| InChI | InChI=1S/C24H51OP/c1-4-7-10-13-16-19-22-26(25,23-20-17-14-11-8-5-2)24-21-18-15-12-9-6-3/h4-24H2,1-3H3 |
| PubChem CID | 65577 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29314900 |
| Tariff Code | 2931498013 |
Safety & GHS
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Corrosive
GHS05
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Health Hazard
GHS07
Hazard statements
- H315 Causes skin irritation
- H317 May cause an allergic skin reaction
- H318 Causes serious eye damage
- H412 Harmful to aquatic life with long lasting effects
Precautionary statements
- P264 Wash thoroughly after handling
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P332+313 IF skin irritation occurs: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, English (US), French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (OCT)3PO
- 1-dioctylphosphoryloctane
- Cyanex 921
- Hostarex PX 324
- Phosphine oxide, trioctyl-
- TOPO
- Tri-n-octylphosphine oxide
- Trioctyl(oxo)-lambda~5~-phosphane
- Trioctylphosphine oxide, Selectophore(TM)
- trioctylphosphino-1-one
Frequently asked questions
What is trioctylphosphine oxide (TOPO) commonly used for?
TOPO is widely used as a ligand in semiconductor manufacturing (e.g., III-V compound growth), a phase-transfer catalyst, and in organic synthesis for stabilizing metal nanoparticles.
What is the chemical formula and molecular weight of trioctylphosphine oxide?
The formula is **[CH₃(CH₂)₇]₃PO**, and the molecular weight is **386.63 g/mol**.
How should trioctylphosphine oxide be stored?
Store TOPO at **ambient temperature** in a tightly sealed container, away from moisture and strong oxidizers.
What purity grades does Molekula offer for trioctylphosphine oxide?
Molekula supplies TOPO in **technical grade (97%+ purity)** and **semiconductor-grade (99.9%+ purity)** for critical applications.
Can Molekula supply trioctylphosphine oxide in bulk quantities?
Yes, we offer TOPO in bulk (minimum order quantities vary; contact us for pricing and availability).
What documentation is provided with a trioctylphosphine oxide order?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **batch-specific documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.