Molekula
4-Toluenesulfonyl chloride
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
4-Toluenesulfonyl chloride is a versatile sulfonylating agent widely used in organic synthesis, pharmaceuticals, and polymer chemistry to introduce tosyl groups for protection, activation, or coupling reactions. This white crystalline solid has a CAS number of 98-59-9, with the molecular formula CH3C6H4SO2Cl and a molecular weight of 190.65. It is stored at ambient conditions but requires careful handling due to its hazardous nature, marked by the signal word "Danger." Molekula supplies 4-Toluenesulfonyl chloride from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Specifications
| Property | Value |
|---|---|
| Appearance | White to Off-white powder |
| Colour (Pt-Co) | ≤ 30 |
| Assay | ⩾ 99.0% |
| Free acid | ≤ 0.1% |
| Toluene-2-sulphonyl chloride | ≤ 1.0% |
| Water (KF) | ≤ 0.5% |
| Initial Melting Point | ⩾ 65.0°C |
| Identification (IR) | Conforms to Reference |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Transport Class | 8 |
| Packing Group | III |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Crystals |
| Melting Point | 69-71 °C |
| Boiling Point | 146 °C at 15 mmHg |
| Vapour Pressure | 0.16 Pa at 25 °C |
Source: PubChem CID 7397 (HSDB, ICSC)
Identification
| Property | Value |
|---|---|
| SKU | 90035481 |
| CAS Number | 98-59-9 |
| IUPAC Name | 4-methylbenzenesulfonyl chloride |
| EC Number | 202-684-8 |
| Molecular Formula | CH3C6H4SO2Cl |
| Molecular Weight | 190.65 |
| Exact Mass | 189.9855 |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)Cl |
| InChIKey | YYROPELSRYBVMQ-UHFFFAOYSA-N |
| InChI | InChI=1S/C7H7ClO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3 |
| PubChem CID | 7397 |
| UN Number | UN3261 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29049940 |
| Tariff Code | 2904990030 |
Safety & GHS
-
Corrosive
GHS05
-
Health Hazard
GHS07
Hazard statements
- H290 May be corrosive to metals
- H315 Causes skin irritation
- H317 May cause an allergic skin reaction
- H318 Causes serious eye damage
Precautionary statements
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P333+313 IF skin irritation or a rash occurs: Get medical advice/attention
- P337+313 If eye irritation persists get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Quality certificates
Molekula Group is certified to ISO 9001:2015 (quality) and ISO 14001:2015 (environmental management), audited by a UKAS-accredited body. Both certificates are valid to 17 May 2028.
Synonyms
- 4-methylbenzene-1-sulfonyl chloride
- 4-Methylbenzenesulfonyl chloride
- p-Methylbenzenesulfonyl chloride
- p-Toluenesulfochloride
- p-Toluenesulfonic acid chloride
- P-TOLUENESULFONYL CHLORIDE
- p-Toluenesulphonyl chloride
- p-Tolylsulfonyl chloride
- p-Tosyl chloride
- Tosyl chloride
Frequently asked questions
What is 4-Toluenesulfonyl chloride (p-TsCl) commonly used for?
It is widely used as a sulfonylating agent in organic synthesis, particularly for converting alcohols to tosylates, and in the preparation of pharmaceutical intermediates, dyes, and agrochemicals.
What is the chemical formula and molecular weight of 4-Toluenesulfonyl chloride?
The formula is **CH₃C₆H₄SO₂Cl**, and the molecular weight is **190.65 g/mol**.
What safety classification does 4-Toluenesulfonyl chloride have?
The product is labeled with the **signal word 'Danger'** due to its corrosive and hazardous properties.
How should 4-Toluenesulfonyl chloride be stored?
Store in a **cool, dry place at ambient temperature**, away from moisture, incompatible materials, and under proper ventilation.
What grades or purities of 4-Toluenesulfonyl chloride does Molekula supply?
Molekula supplies **high-purity (98%+)** 4-Toluenesulfonyl chloride suitable for research, development, and industrial applications.
Can Molekula supply 4-Toluenesulfonyl chloride in bulk quantities?
Yes, we offer **bulk packaging options** (e.g., drums, IBCs) for large-scale industrial or commercial needs—please inquire for specific quantities.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.