Molekula
4-Toluenesulfonyl chloride
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
4-Toluenesulfonyl chloride is a versatile sulfonylating agent widely used in organic synthesis, pharmaceuticals, and polymer chemistry to introduce tosyl groups for protection, activation, or coupling reactions. This white crystalline solid has a CAS number of 98-59-9, with the molecular formula CH3C6H4SO2Cl and a molecular weight of 190.65. It is stored at ambient conditions but requires careful handling due to its hazardous nature, marked by the signal word "Danger." Molekula supplies 4-Toluenesulfonyl chloride from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Specifications
| Property | Value |
|---|---|
| Appearance | White to Off-white powder |
| Colour (Pt-Co) | ≤ 30 |
| Assay | ⩾ 99.0% |
| Free acid | ≤ 0.1% |
| Toluene-2-sulphonyl chloride | ≤ 1.0% |
| Water (KF) | ≤ 0.5% |
| Initial Melting Point | ⩾ 65.0°C |
| Identification (IR) | Conforms to Reference |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Transport Class | 8 |
| Packing Group | III |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Crystals |
| Melting Point | 69-71 °C |
| Boiling Point | 146 °C at 15 mmHg |
| Vapour Pressure | 0.16 Pa at 25 °C |
Source: PubChem CID 7397 (HSDB, ICSC)
Identification
| Property | Value |
|---|---|
| SKU | 90035481 |
| CAS Number | 98-59-9 |
| IUPAC Name | 4-methylbenzenesulfonyl chloride |
| EC Number | 202-684-8 |
| Molecular Formula | CH3C6H4SO2Cl |
| Molecular Weight | 190.65 |
| Exact Mass | 189.9855 |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)Cl |
| InChIKey | YYROPELSRYBVMQ-UHFFFAOYSA-N |
| InChI | InChI=1S/C7H7ClO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3 |
| PubChem CID | 7397 |
| UN Number | UN3261 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29049940 |
| Tariff Code | 2904990030 |
Safety & GHS
-
Corrosive
GHS05
-
Health Hazard
GHS07
Hazard statements
- H290 May be corrosive to metals
- H315 Causes skin irritation
- H317 May cause an allergic skin reaction
- H318 Causes serious eye damage
Precautionary statements
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P333+313 IF skin irritation or a rash occurs: Get medical advice/attention
- P337+313 If eye irritation persists get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 4-methylbenzene-1-sulfonyl chloride
- 4-Methylbenzenesulfonyl chloride
- p-Methylbenzenesulfonyl chloride
- p-Toluenesulfochloride
- p-Toluenesulfonic acid chloride
- P-TOLUENESULFONYL CHLORIDE
- p-Toluenesulphonyl chloride
- p-Tolylsulfonyl chloride
- p-Tosyl chloride
- Tosyl chloride
Frequently asked questions
What is 4-Toluenesulfonyl chloride (p-TsCl) commonly used for?
It is widely used as a sulfonylating agent in organic synthesis, particularly for converting alcohols to tosylates, and in the preparation of pharmaceutical intermediates, dyes, and agrochemicals.
What is the chemical formula and molecular weight of 4-Toluenesulfonyl chloride?
The formula is **CH₃C₆H₄SO₂Cl**, and the molecular weight is **190.65 g/mol**.
What safety classification does 4-Toluenesulfonyl chloride have?
The product is labeled with the **signal word 'Danger'** due to its corrosive and hazardous properties.
How should 4-Toluenesulfonyl chloride be stored?
Store in a **cool, dry place at ambient temperature**, away from moisture, incompatible materials, and under proper ventilation.
What grades or purities of 4-Toluenesulfonyl chloride does Molekula supply?
Molekula supplies **high-purity (98%+)** 4-Toluenesulfonyl chloride suitable for research, development, and industrial applications.
Can Molekula supply 4-Toluenesulfonyl chloride in bulk quantities?
Yes, we offer **bulk packaging options** (e.g., drums, IBCs) for large-scale industrial or commercial needs—please inquire for specific quantities.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.