Molekula
Trimethyl orthoformate
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Trimethyl orthoformate is an organic ester used as a methylating agent, solvent, and reagent in chemical synthesis, particularly for protecting carbonyl groups and preparing methoxy derivatives. It appears as a colorless liquid with a pungent odor. CAS 149-73-5, molecular formula CH(OCH3)3, molecular weight 106.12 g/mol, stored at ambient conditions. The product carries a **Danger** signal word due to its flammability and toxicity. Molekula supplies Trimethyl orthoformate from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Colourless to light yellow liquid |
| Water | ≤0.05% |
| Assay | ≥99% |
| Methanol | ≤0.3% |
| Methyl formate | ≤0.2% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Flash Point | 13 °C |
| Transport Class | 3 |
| Packing Group | II |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Colorless liquid |
| Odour | Pungent odor |
| Boiling Point | 100.6 °C at 760 mmHg |
| Vapour Pressure | 81.4 mmHg |
| Refractive Index | 1.3773 |
Source: PubChem CID 9005 (HSDB, Haz-Map)
Identification
| Property | Value |
|---|---|
| SKU | 13254988 |
| CAS Number | 149-73-5 |
| IUPAC Name | trimethoxymethane |
| EC Number | 205-745-7 |
| Molecular Formula | CH(OCH3)3 |
| Molecular Weight | 106.12 |
| Exact Mass | 106.063 |
| SMILES | COC(OC)OC |
| InChIKey | PYOKUURKVVELLB-UHFFFAOYSA-N |
| InChI | InChI=1S/C4H10O3/c1-5-4(6-2)7-3/h4H,1-3H3 |
| PubChem CID | 9005 |
| UN Number | UN3272 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29159018 |
| Tariff Code | 2915907045 |
Safety & GHS
-
Flammable
GHS02
-
Health Hazard
GHS07
Hazard statements
- H225 Highly flammable liquid and vapour
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
Precautionary statements
- P210 Keep away from heat/sparks/open flames/hot surfaces - No smoking
- P241 Use explosion-proof electrical/ventilating/lighting equipment
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P303+361 IF ON SKIN (or hair): Remove immediately all contaminated clothing. Rinse with water/shower
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P353 Rinse skin with water/shower
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Russian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- Methane, trimethoxy-
- Methoxymethylal
- Methyl orthoformate
- Methylester kyseliny orthomravenci
- Orthoformic acid methyl ester
- Orthoformic acid, trimethyl ester
- Orthomravencan methylnaty
- PERMA-FLO OF
- Trimethoxymethane
- Trimethylester kyseliny orthomravenci
Frequently asked questions
What is trimethyl orthoformate commonly used for?
Trimethyl orthoformate is primarily used as a reagent in organic synthesis, such as for the protection of aldehydes and ketones, and in the preparation of esters and other functional groups.
What is the chemical formula and molecular weight of trimethyl orthoformate?
The chemical formula is **CH(OCH₃)₃**, and the molecular weight is **106.12 g/mol**.
How should trimethyl orthoformate be stored?
Store in a tightly sealed container at **ambient temperature**, away from moisture and sources of ignition.
What grades of trimethyl orthoformate does Molekula supply?
Molekula supplies **technical and reagent grades** of trimethyl orthoformate, depending on purity requirements.
Can Molekula supply trimethyl orthoformate in bulk quantities?
Yes, Molekula can provide trimethyl orthoformate in bulk, with quantities tailored to your specific needs.
What documentation is provided with an order of trimethyl orthoformate?
Each order includes a **Certificate of Analysis (CoA)**, Material Safety Data Sheet (MSDS), and a product specification sheet.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.