Molekula
Trifluoroacetic acid
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Trifluoroacetic acid is a strong organic acid used extensively in chemical synthesis, particularly in peptide coupling and as a reagent in the synthesis of pharmaceuticals and fine chemicals. It is a colorless liquid with a pungent odor. CAS: 76-05-1, Molecular formula: CF3COOH, Molecular weight: 114.02 g/mol. Store at ambient temperature. Hazardous: Signal word Danger. Molekula supplies Trifluoroacetic acid from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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1 L — £340.00 per pack ex VAT · £408.00 inc. VAT
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100 mL — £55.00 per pack ex VAT · £66.00 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Clear, colourless liquid |
| Assay/Purity | ≥ 99.5% |
| Water | ≤ 0.50% |
| Chloride (Cl-) | ≤ 0.001% |
| UV Absorption (280nm) | ≤ 0.05nm |
| Sulphates (SO4)(2-) | ≤ 0.001% |
| Fluoride (F-) | ≤ 0.005% |
| UV Absorbance (260nm) | ≤ 0.90nm |
| UV Absorbance (270nm) | ≤ 0.10nm |
| UV Absorbance (290nm) | ≤ 0.04nm |
| UV Absorbance (300nm) | ≤ 0.03nm |
| UV Absorbance (320nm) | ≤ 0.025nm |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Flash Point | 100 °C |
| Transport Class | 8 |
| Packing Group | I |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Liquid |
| Odour | Sharp biting odor |
| Melting Point | -15 °C |
| Boiling Point | 72 °C |
| Density | 1.5 (relative, water = 1) |
| Vapour Pressure | 11 kPa at 20 °C |
| Refractive Index | 1.2850 |
| pKa | pKa = 0.3 |
Source: PubChem CID 6422 (HSDB, ICSC)
Identification
| Property | Value |
|---|---|
| SKU | 90004981 |
| CAS Number | 76-05-1 |
| IUPAC Name | 2,2,2-trifluoroacetic acid |
| EC Number | 200-929-3 |
| Molecular Formula | CF3COOH |
| Molecular Weight | 114.02 |
| Exact Mass | 113.9929 |
| SMILES | C(=O)(C(F)(F)F)O |
| InChIKey | DTQVDTLACAAQTR-UHFFFAOYSA-N |
| InChI | InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) |
| PubChem CID | 6422 |
| UN Number | UN2699 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29159018 |
| Tariff Code | 2915909043 |
Safety & GHS
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Corrosive
GHS05
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Health Hazard
GHS07
Hazard statements
- H314 (sub cat. 1A) Causes severe skin burns and eye damage
- H318 Causes serious eye damage
- H332 Harmful if inhaled
- H412 Harmful to aquatic life with long lasting effects
Precautionary statements
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P303+361 IF ON SKIN (or hair): Remove immediately all contaminated clothing. Rinse with water/shower
- P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Russian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 2,2,2-trifluoroacetic acid
- Acetic acid, 2,2,2-trifluoro-
- Acetic acid, trifluoro-
- Acid, Trifluoroacetic
- acide trifluoroacetique
- Kyselina trifluoroctova
- Perfluoroacetic acid
- Trifluoracetic acid
- Trifluoressigsaeure
- Trifluoroethanoic acid
Frequently asked questions
What is trifluoroacetic acid used for?
It is commonly used as a reagent in organic synthesis, particularly in peptide synthesis and as a catalyst or solvent in various chemical reactions.
What is the chemical formula and molecular weight of trifluoroacetic acid?
The formula is CF3COOH with a molecular weight of 114.02 g/mol.
How should trifluoroacetic acid be stored?
It should be stored at ambient temperature, away from incompatible materials and moisture.
What grade is available for trifluoroacetic acid?
Molekula offers trifluoroacetic acid in reagent grade, suitable for laboratory and industrial applications.
Can Molekula supply trifluoroacetic acid in bulk?
Yes, Molekula can supply trifluoroacetic acid in bulk quantities; please contact our sales team for pricing and availability.
What documentation comes with a purchase of trifluoroacetic acid?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS) with the shipment.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.