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Molekula

Molekula

Tiagabine hydrochloride

SKU 23658161 CAS 145821-59-6 C20H25NO2S2 · HCl MW 412.0 Made to order Bulk quantities on request

Supplying 4,500+ customers in over 80 countries

ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need

Tiagabine hydrochloride is a selective GABA uptake inhibitor primarily used as an anticonvulsant medication to treat epilepsy and, in some cases, neuropathic pain. It works by increasing the availability of the neurotransmitter GABA in the brain. This chemical has a CAS number of 145821-59-6, with the molecular formula C20H25NO2S2 · HCl and a molecular weight of 412.0 g/mol. It requires storage between 2 to 8°C and carries a signal word of "Warning."

Molekula supplies Tiagabine hydrochloride at ≥ 99% purity (HPLC) in 10 mg packs, from £74.52 inc. VAT. It is made or sourced to order. Every batch ships with a certificate of analysis, and safety data sheets are available in 6 languages. Larger quantities, up to multi-tonne, are quoted on request.

Expect a response within hours Speak to a chemist: +44 (0) 3302 000333

Example image for illustration only. Other packaging and pack sizes are available.

Pricing & pack sizes

Pack sizes & pricing

On backorder — expected to ship by 5 December 2026

These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.

Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.

  • 10 mg — £62.10 per pack ex VAT · £74.52 inc. VAT

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Specifications

Property Value
Appearance White to Off-white crystalline powder
Melting Point 192.6-195.1°C
Purity (HPLC) ≥ 99%
Water (KF) <0.4%
S-Isomer <1%

Storage & handling

Property Value
Storage Temperature 2 to 8 °C
Acidity Acid

Identification

Property Value
SKU 23658161
CAS Number 145821-59-6
IUPAC Name (3R)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-enyl]piperidine-3-carboxylic acid;hydrochloride
Molecular Formula C20H25NO2S2 · HCl
Molecular Weight 412.0
Exact Mass 411.1093
SMILES CC1=C(SC=C1)C(=CCCN2CCC[C@H](C2)C(=O)O)C3=C(C=CS3)C.Cl
InChIKey YUKARLAABCGMCN-PKLMIRHRSA-N
InChI InChI=1S/C20H25NO2S2.ClH/c1-14-7-11-24-18(14)17(19-15(2)8-12-25-19)6-4-10-21-9-3-5-16(13-21)20(22)23;/h6-8,11-12,16H,3-5,9-10,13H2,1-2H3,(H,22,23);1H/t16-;/m1./s1
PubChem CID 91274
REACH Code Y110
HTS Code 2934.99.90.01
Tariff Code 2934999090

Safety & GHS

Warning
  • GHS pictogram — Health Hazard Health Hazard GHS07
  • GHS pictogram — Serious Health Hazard Serious Health Hazard GHS08

Hazard statements

  • H319 Causes serious eye irritation
  • H351 Suspected of causing cancer

Precautionary statements

  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray
  • P280 Wear protective gloves/protective clothing/eye protection/face protection
  • P302+352 IF ON SKIN: Wash with soap and water
  • P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
  • P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing

Documents

Certificate of Analysis (CoA) by batch

Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.

Quality certificates

Molekula Group is certified to ISO 9001:2015 (quality) and ISO 14001:2015 (environmental management), audited by a UKAS-accredited body. Both certificates are valid to 17 May 2028.

Synonyms

  • (-)-(R)-1-(4,4-Bis(3-methyl-2-thienyl)-3-butenyl)nipecotic acid, hydrochloride
  • Abbott 70569.HCl
  • ABBOTT-70569 HYDROCHLORIDE
  • Abbott-70569.1
  • C20H26ClNO2S2
  • Gabatril
  • Gabitril
  • Gabitril (TN)
  • TIAGABINE HCl
  • Tiagabine hydrochloride (USAN:USP)

Frequently asked questions

What is Tiagabine hydrochloride used for?

Tiagabine hydrochloride is primarily used as an anticonvulsant medication to treat epilepsy by enhancing GABA activity in the brain.

What is the chemical formula and molecular weight of Tiagabine hydrochloride?

The chemical formula is C20H25NO2S2 · HCl, and the molecular weight is 412.0 g/mol.

How should Tiagabine hydrochloride be stored?

Store at 2 to 8°C to maintain stability and potency.

What grade of Tiagabine hydrochloride does Molekula supply?

Molekula supplies Tiagabine hydrochloride with a purity of ≥ 99% (HPLC) for research and development purposes.

Can Molekula supply Tiagabine hydrochloride in bulk quantities?

Yes, bulk quantities of Tiagabine hydrochloride are available upon request, subject to minimum order quantities and regulatory compliance.

What documentation comes with an order of Tiagabine hydrochloride?

Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and batch-specific documentation for traceability.

Where can I buy Tiagabine hydrochloride?

Directly from Molekula, which lists Tiagabine hydrochloride in 10 mg packs from £74.52 inc. VAT, with a certificate of analysis for every batch. Larger quantities are quoted on request. Molekula's offices: United Kingdom, France, Spain, Germany, Italy, United States and China.

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