Molekula
Spironolactone
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Spironolactone is a potassium-sparing diuretic and aldosterone antagonist used in the treatment of hypertension, heart failure, and edema. It functions by blocking aldosterone receptors in the kidneys, promoting sodium and water excretion while retaining potassium. Available in powder form, it has a molecular weight of 416.57 g/mol, a molecular formula of C24H32O4S, and a CAS number of 52-01-7. Store at ambient temperature. Handle with care due to its signal word: Danger. Molekula supplies Spironolactone from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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5 g — £165.10 per pack ex VAT · £198.12 inc. VAT
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Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to yellow/off-white powder |
| Melting Point | 198 - 209°C |
| Loss on Drying | ≤ 0.5% |
| Assay | 97.5 - 102.0 % |
| Sulphated Ash | 0.1% max |
| Specific optical rotation | -41 to -45° |
| Identification (IR.UV) | Conforms to structure |
| Free mercapto compounds | ≤ 0.1ml |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Flash Point | 0 °C |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Light cream-colored to light tan, crystalline powder |
| Odour | Mild mercaptan-like odor |
| Melting Point | 134-135 °C |
| Boiling Point | 134 °C |
| Water Solubility | 22 mg/L at 25 °C |
| Solubility (other solvents) | Soluble in most organic solvents |
| log P (octanol/water) | 2.78 |
Source: PubChem CID 5833 (HSDB)
Identification
| Property | Value |
|---|---|
| SKU | 49631028 |
| CAS Number | 52-01-7 |
| IUPAC Name | S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate |
| EC Number | 200-133-6 |
| Molecular Formula | C24H32O4S |
| Molecular Weight | 416.57 |
| Exact Mass | 416.2021 |
| SMILES | CC(=O)S[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]5([C@]4(CC3)C)CCC(=O)O5)C |
| InChIKey | LXMSZDCAJNLERA-ZHYRCANASA-N |
| InChI | InChI=1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1 |
| PubChem CID | 5833 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 2932.20.5050 |
| Tariff Code | 2932209090 |
Safety & GHS
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Health Hazard
GHS07
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Serious Health Hazard
GHS08
Hazard statements
- H302+H312+H332 Harmful if swallowed, in contact with skin or if inhaled
- H351 Suspected of causing cancer
- H360 May damage fertility or the unborn child
- H373 May cause damage to organs through prolonged or repeated exposure
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P263 Avoid contact during pregnancy/while nursing
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P302+P352 IF ON SKIN: Wash with soap and water
- P304+P341 IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing
- P305+P351+P338 IF IN EYES: Rinse continuously with water for several minutes. Remove contact lenses if present and easy to do, continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
- P501 Dispose of contents/container to an approved waste disposal plant
Documents
Safety Data Sheets (SDS)
Available in English, German, Spanish, French, Italian, Portuguese, Arabic, Dutch.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- Abbolactone
- Aldactone
- Espironolactona
- Spiresis
- Spirolactone
- Spironolactonum
- spironolattone
- Uractone
- Verospirone
- Xenalon
Frequently asked questions
What is spironolactone used for?
Spironolactone is primarily used as a potassium-sparing diuretic and is prescribed for conditions such as heart failure, hypertension, and edema. It is also used off-label for hormonal conditions like acne and hirsutism.
What is the chemical formula and molecular weight of spironolactone?
The chemical formula of spironolactone is C24H32O4S, and its molecular weight is 416.57 g/mol.
How should spironolactone be stored?
Spironolactone should be stored at ambient temperature, away from moisture and light, and kept in a tightly closed container.
What grade of spironolactone does Molekula supply?
Molekula supplies spironolactone in research-grade purity, suitable for laboratory use and non-pharmaceutical applications.
Can Molekula supply spironolactone in bulk quantities?
Yes, Molekula can supply spironolactone in bulk quantities—please contact our sales team for pricing and availability.
What documentation comes with a spironolactone order?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS); additional documentation can be provided upon request.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.