Molekula
S-(-)-Nicotine
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
S-(-)-Nicotine is a chiral form of nicotine, a naturally occurring alkaloid with potent pharmacological activity. It is used in research, pharmaceutical development, and nicotine replacement therapies. It also serves as the active ingredient in restricted-use insecticide products for greenhouse ornamental plants such as poinsettias and chrysanthemums. Available with a CAS number of 54-11-5, molecular formula C10H14N2, and molecular weight 162.23 g/mol. Stored at ambient temperature. Hazard classification includes signal word Danger. Molekula supplies S-(-)-Nicotine from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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25 g — £93.50 per pack ex VAT · £112.20 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Colourless to brown viscous liquid |
| Water | 2.5% typical |
| Specific rotation | -140 to -152 |
| Assay (Anhydrous) | 99.8% anhydrous |
| Assay(Hydrate) | >95% typical >97% |
| Nicotine-trans-N-Oxide | see total Nictoine-N-Oxide below (<0.05%) |
| Nicotine-cis-N-Oxide | see total Nictoine-N-Oxide below (<0.05%) |
| Nornicotine | ≤0.05% |
| Anabasine | ≤0.05% |
| Anatabine | ≤0.05% |
| Total Nicotine-N-Oxides | ≤0.05% |
| Total Impurities (spec. and unspec.) | ≤0.25% |
| Any Unidentified Impurity | ≤0.05% |
| beta-nicotyrine | ≤0.05% |
| Nicotine | ≥95.0% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Flash Point | 101 °C |
| Transport Class | 6.1 |
| Packing Group | II |
| Acidity | Base |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Colorless to pale yellow, oily liquid |
| Odour | Fish-like odor when warm |
| Melting Point | -79 °C |
| Boiling Point | 247 °C |
| Density | 1.01 (relative, water = 1) |
| Water Solubility | 1000 g/L at 25 °C (miscible) |
| Vapour Pressure | 0.006 kPa at 20 °C |
| Refractive Index | 1.5282 |
| pKa | pKa = 8.5 |
| log P (octanol/water) | 1.17 |
Source: PubChem CID 89594 (HSDB, DrugBank, ICSC)
Identification
| Property | Value |
|---|---|
| SKU | 90028684 |
| CAS Number | 54-11-5 |
| IUPAC Name | 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine |
| EC Number | 200-193-3 |
| Molecular Formula | C10H14N2 |
| Molecular Weight | 162.23 |
| Exact Mass | 162.1157 |
| SMILES | CN1CCC[C@H]1C2=CN=CC=C2 |
| InChIKey | SNICXCGAKADSCV-JTQLQIEISA-N |
| InChI | InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1 |
| PubChem CID | 89594 |
| UN Number | UN1654 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29397900 |
| Tariff Code | 2939791000 |
Safety & GHS
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Corrosive
GHS05
-
Toxic
GHS06
-
Hazardous to the Environment
GHS09
Hazard statements
- H300 +H310 + H330 Fatal if swallowed, in contact with skin or if inhaled
- H315 Causes skin irritation
- H318 Causes serious eye damage
- H411 Toxic to aquatic life with long lasting effects
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P501 Dispose of contents/container to an approved waste disposal plant
Documents
Safety Data Sheets (SDS)
Available in English, English (US), French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (S)-3-(1-methylpyrrolidin-2-yl)pyridine
- 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
- Fumetobac
- Habitrol
- L-Nicotine
- Nicocide
- Nicoderm
- Nicoderm Cq
- nicotine
- Nicotrol
Frequently asked questions
What is S-(-)-Nicotine used for?
S-(-)-Nicotine is primarily used in research applications, including studies on nicotinic acetylcholine receptors and addiction mechanisms.
What is the chemical formula and molecular weight of S-(-)-Nicotine?
The formula is C10H14N2 with a molecular weight of 162.23 g/mol.
How should S-(-)-Nicotine be stored?
It should be stored at ambient temperature, protected from light and moisture.
What grade of S-(-)-Nicotine is available?
Available in research grade; purity details are provided in the certificate of analysis.
Can Molekula supply S-(-)-Nicotine in bulk?
Yes, bulk quantities are available upon request; please contact our sales team for pricing and availability.
What documentation comes with an order of S-(-)-Nicotine?
Each order includes a certificate of analysis (CoA) and safety data sheet (SDS) with the shipment.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.