Molekula
Podophyllotoxin
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Podophyllotoxin is a naturally occurring lignan found in the roots and rhizomes of *Podophyllum* plants, primarily used in pharmaceuticals as a precursor for the synthesis of etoposide and teniposide, which are chemotherapy drugs. It is the active ingredient in topical genital wart preparations such as Condylox and is used in laboratory research as a tubulin-binding, microtubule-destabilising antimitotic agent. It is also studied for its potential antiviral and antiproliferative properties. Podophyllotoxin has a CAS number of 518-28-5, a molecular formula of C22H22O8, and a molecular weight of 414.41 g/mol. It must be stored between 2 to 8°C and carries a **Danger** signal word due to its high toxicity. Molekula supplies Podophyllotoxin from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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1 g — £30.90 per pack ex VAT · £37.08 inc. VAT
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5 g — £76.30 per pack ex VAT · £91.56 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White/ light yellow powder |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Transport Class | 6.1 |
| Packing Group | III |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Solvated crystals |
| Melting Point | 228 °C |
| Vapour Pressure | 8.3 × 10⁻¹⁵ mmHg at 25 °C (Estimated) |
| log P (octanol/water) | 2.01 |
Source: PubChem CID 10607 (HSDB, DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 52308554 |
| CAS Number | 518-28-5 |
| IUPAC Name | (5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one |
| EC Number | 208-250-4 |
| Molecular Formula | C22H22O8 |
| Molecular Weight | 414.41 |
| Exact Mass | 414.1315 |
| SMILES | COC1=CC(=CC(=C1OC)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](C4=CC5=C(C=C24)OCO5)O |
| InChIKey | YJGVMLPVUAXIQN-XVVDYKMHSA-N |
| InChI | InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1 |
| PubChem CID | 10607 |
| UN Number | UN3462 |
| REACH Code | Y110 |
| HTS Code | 2932.20.4500 |
| Tariff Code | 2932209090 |
Safety & GHS
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Toxic
GHS06
Hazard statements
- H301 + H311 + H331 Toxic if swallowed, in contact with skin or if inhaled
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- Condyline
- Condylox
- Podofilm
- Podofilox
- Podofilox (USAN)
- Podophilox
- Podophyllinic acid lactone
- Podophyllotoxin 7
- Wartec
- Warticon
Frequently asked questions
What is podophyllotoxin primarily used for?
Podophyllotoxin is primarily used as a starting material in the synthesis of chemotherapeutic drugs like etoposide and teniposide, and in research for its cytotoxic and antiviral properties.
What is the chemical formula and molecular weight of podophyllotoxin?
The chemical formula is **C22H22O8** and the molecular weight is **414.41 g/mol**.
How should podophyllotoxin be stored?
Store podophyllotoxin at **2 to 8°C** in a dry, well-ventilated area, away from incompatible substances.
What grades of podophyllotoxin does Molekula supply?
Molekula supplies podophyllotoxin in **pharmaceutical-grade** and **analytical-grade** purity levels.
Can Molekula supply podophyllotoxin in bulk quantities?
Yes, Molekula can supply podophyllotoxin in bulk, with quantities tailored to your research or production needs.
What documentation comes with a podophyllotoxin order?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **batch-specific documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.