Molekula
Naloxone hydrochloride
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Naloxone hydrochloride is an opioid antagonist used primarily in emergency medicine to rapidly reverse opioid overdose by binding to opioid receptors without activating them. This high-purity pharmaceutical intermediate is critical for saving lives in critical care settings. Catalogue details: CAS 357-08-4, molecular formula C19H21NO4·HCl, molecular weight 363.8353 g/mol, stored at ambient conditions, signal word Warning. Molekula supplies Naloxone hydrochloride from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White solid |
| Melting Point | 138 °C |
| Solubility | Soluble in water at 15.0 mg/ml and DMSO at 20.0 mg/ml |
| TLC | Rf: 0.73 (DCM: MeOH: NH3 20: 1: 0.1 ) |
| Carbon (C) | 58.30% |
| Purity | ≥ 99.0% |
| Identification (NMR) | Consistent with structure |
| Identification (MS) | Consistent with structure |
| Hydrogen (H) | 6.36% |
| Nitrogen (N) | 3.33% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 89987071 |
| CAS Number | 357-08-4 |
| IUPAC Name | (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride |
| EC Number | 206-611-0 |
| Molecular Formula | C19H21NO4 · HCl |
| Molecular Weight | 363.8353 |
| Exact Mass | 363.1237 |
| SMILES | C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O.Cl |
| InChIKey | RGPDIGOSVORSAK-STHHAXOLSA-N |
| InChI | InChI=1S/C19H21NO4.ClH/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11;/h2-4,14,17,21,23H,1,5-10H2;1H/t14-,17+,18+,19-;/m1./s1 |
| PubChem CID | 5464092 |
| REACH Code | Y110 |
| HTS Code | 29391920 |
| Tariff Code | 2939190000 |
Safety & GHS
-
Health Hazard
GHS07
Hazard statements
- H302 Harmful if swallowed
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- Anhydrous naloxone hydrochloride
- Evzio
- KLOXXADO
- Naloxone HCl
- Naloxone hydrochloride anhydrous
- Naloxoni hydrochloridum anhydrous
- NIH 7890
- REZENOPY
- RIVIVE
- TARGINIQ COMPONENT NALOXONE HYDROCHLORIDE
Frequently asked questions
What is naloxone hydrochloride commonly used for?
Naloxone hydrochloride is primarily used as an opioid antagonist to rapidly reverse opioid overdose by binding to opioid receptors and blocking their effects.
What is the chemical formula and molecular weight of naloxone hydrochloride?
The chemical formula is **C₁₉H₂₁NO₄·HCl**, and the molecular weight is **363.8353 g/mol**.
What safety classification does naloxone hydrochloride fall under?
Naloxone hydrochloride carries a **Signal Word: Warning** under GHS classification, indicating moderate hazard.
How should naloxone hydrochloride be stored?
Store at **ambient temperature** in a dry, well-ventilated area, away from incompatible substances.
Does Molekula supply naloxone hydrochloride in bulk quantities?
Yes, Molekula can provide naloxone hydrochloride in bulk, with quantities tailored to your requirements—contact us for pricing and availability.
What documentation is provided with a naloxone hydrochloride order?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS/SDS)**, and **batch-specific documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.