Molekula
25-Hydroxyvitamin D3
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
25-Hydroxyvitamin D3 is the major circulating form of vitamin D in the blood, essential for calcium metabolism, bone health, and immune function. Under the name calcifediol, it is the active pharmaceutical ingredient in prescription vitamin D medicines and is also formulated as a nutraceutical ingredient. It serves as a key biomarker in clinical diagnostics and is used in research for studying metabolic and endocrine pathways. CAS 19356-17-3, molecular formula C27H44O2 · H2O, molecular weight 400.64. Requires storage at -15 to -20°C; signal word is Danger due to potential hazards. Molekula supplies 25-Hydroxyvitamin D3 from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to off-white solid |
| Purity (HPLC) | ≥ 99.0% |
| Loss on Drying | ≤ 5.0% (20°C/min, 30 - 450°C) |
| Solubility | Slightly soluble in chloroform and methanol |
| Identification (1H-NMR,IR) | Conforms to Reference |
| Defined Potency (mass balance method) | ≥ 94.0% w/w (%=100-[(Weight loss by TGA) x (HPLC Purity)/100]) |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Transport Class | 6.1 |
| Packing Group | II |
| Acidity | Acid |
Identification
| Property | Value |
|---|---|
| SKU | 89983933 |
| CAS Number | 19356-17-3 |
| IUPAC Name | (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol |
| EC Number | 242-990-9 |
| Molecular Formula | C27H44O2 · H2O |
| Molecular Weight | 400.64 |
| Exact Mass | 400.3341 |
| SMILES | C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C |
| InChIKey | JWUBBDSIWDLEOM-DTOXIADCSA-N |
| InChI | InChI=1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1 |
| PubChem CID | 5283731 |
| UN Number | UN2811 |
| REACH Code | Y110 |
| HTS Code | 29362900 |
| Tariff Code | 2936290000 |
Safety & GHS
-
Toxic
GHS06
-
Serious Health Hazard
GHS08
Hazard statements
- H301 + H311 Toxic if swallowed or in contact with skin
- H330 Fatal if inhaled
- H372 Causes damage to organs through prolonged or repeated exposure
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P303+361 IF ON SKIN (or hair): Remove immediately all contaminated clothing. Rinse with water/shower
- P308+313 IF exposed or concerned: Get medical advice/attention
- P310 Immediately call a POISON CENTER or doctor/physician
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 25-Hydroxycholescalciferol
- 5,6-cis-25-Hydroxyvitamin D3
- 9,10-Secocholesta-5,7,10(19)-triene-3beta,25-diol
- Calcidiol
- Calcifediol
- Calcifediol anhydrous
- Calcifediolum
- Cholecalciferol, 25-hydroxy-
- Didrogyl
- Rayaldee
Frequently asked questions
What is 25-Hydroxyvitamin D3 (25(OH)D3) used for?
25-Hydroxyvitamin D3 is primarily used as a nutritional supplement, biomarker for vitamin D status, and in research for studying vitamin D metabolism and deficiency.
What is the chemical formula and molecular weight of 25-Hydroxyvitamin D3?
The chemical formula is **C<sub>27</sub>H<sub>44</sub>O<sub>2</sub> · H<sub>2</sub>O** (hydrate form), with a molecular weight of **400.64 g/mol**.
How should 25-Hydroxyvitamin D3 be stored?
Store at **-15 to -20°C** to maintain stability and prevent degradation.
What grades or purities of 25-Hydroxyvitamin D3 does Molekula supply?
Molekula supplies **analytical and research-grade 25-Hydroxyvitamin D3** with high purity for laboratory and clinical applications.
Can Molekula supply 25-Hydroxyvitamin D3 in bulk quantities?
Yes, Molekula can provide **bulk quantities** of 25-Hydroxyvitamin D3 upon request, depending on availability and regulatory compliance.
What documentation comes with an order of 25-Hydroxyvitamin D3?
Each order includes a **Certificate of Analysis (CoA)**, Material Safety Data Sheet (MSDS), and batch-specific documentation for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.