Molekula
25-Hydroxyvitamin D3
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
25-Hydroxyvitamin D3 is the major circulating form of vitamin D in the blood, essential for calcium metabolism, bone health, and immune function. Under the name calcifediol, it is the active pharmaceutical ingredient in prescription vitamin D medicines and is also formulated as a nutraceutical ingredient. It serves as a key biomarker in clinical diagnostics and is used in research for studying metabolic and endocrine pathways. CAS 19356-17-3, molecular formula C27H44O2 · H2O, molecular weight 400.64. Requires storage at -15 to -20°C; signal word is Danger due to potential hazards. Molekula supplies 25-Hydroxyvitamin D3 from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to off-white solid |
| Purity (HPLC) | ≥ 99.0% |
| Loss on Drying | ≤ 5.0% (20°C/min, 30 - 450°C) |
| Solubility | Slightly soluble in chloroform and methanol |
| Identification (1H-NMR,IR) | Conforms to Reference |
| Defined Potency (mass balance method) | ≥ 94.0% w/w (%=100-[(Weight loss by TGA) x (HPLC Purity)/100]) |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Transport Class | 6.1 |
| Packing Group | II |
| Acidity | Acid |
Identification
| Property | Value |
|---|---|
| SKU | 89983933 |
| CAS Number | 19356-17-3 |
| IUPAC Name | (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol |
| EC Number | 242-990-9 |
| Molecular Formula | C27H44O2 · H2O |
| Molecular Weight | 400.64 |
| Exact Mass | 400.3341 |
| SMILES | C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C |
| InChIKey | JWUBBDSIWDLEOM-DTOXIADCSA-N |
| InChI | InChI=1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1 |
| PubChem CID | 5283731 |
| UN Number | UN2811 |
| REACH Code | Y110 |
| HTS Code | 29362900 |
| Tariff Code | 2936290000 |
Safety & GHS
-
Toxic
GHS06
-
Serious Health Hazard
GHS08
Hazard statements
- H301 + H311 Toxic if swallowed or in contact with skin
- H330 Fatal if inhaled
- H372 Causes damage to organs through prolonged or repeated exposure
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P303+361 IF ON SKIN (or hair): Remove immediately all contaminated clothing. Rinse with water/shower
- P308+313 IF exposed or concerned: Get medical advice/attention
- P310 Immediately call a POISON CENTER or doctor/physician
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Quality certificates
Molekula Group is certified to ISO 9001:2015 (quality) and ISO 14001:2015 (environmental management), audited by a UKAS-accredited body. Both certificates are valid to 17 May 2028.
Synonyms
- 25-Hydroxycholescalciferol
- 5,6-cis-25-Hydroxyvitamin D3
- 9,10-Secocholesta-5,7,10(19)-triene-3beta,25-diol
- Calcidiol
- Calcifediol
- Calcifediol anhydrous
- Calcifediolum
- Cholecalciferol, 25-hydroxy-
- Didrogyl
- Rayaldee
Frequently asked questions
What is 25-Hydroxyvitamin D3 (25(OH)D3) used for?
25-Hydroxyvitamin D3 is primarily used as a nutritional supplement, biomarker for vitamin D status, and in research for studying vitamin D metabolism and deficiency.
What is the chemical formula and molecular weight of 25-Hydroxyvitamin D3?
The chemical formula is **C<sub>27</sub>H<sub>44</sub>O<sub>2</sub> · H<sub>2</sub>O** (hydrate form), with a molecular weight of **400.64 g/mol**.
How should 25-Hydroxyvitamin D3 be stored?
Store at **-15 to -20°C** to maintain stability and prevent degradation.
What grades or purities of 25-Hydroxyvitamin D3 does Molekula supply?
Molekula supplies **analytical and research-grade 25-Hydroxyvitamin D3** with high purity for laboratory and clinical applications.
Can Molekula supply 25-Hydroxyvitamin D3 in bulk quantities?
Yes, Molekula can provide **bulk quantities** of 25-Hydroxyvitamin D3 upon request, depending on availability and regulatory compliance.
What documentation comes with an order of 25-Hydroxyvitamin D3?
Each order includes a **Certificate of Analysis (CoA)**, Material Safety Data Sheet (MSDS), and batch-specific documentation for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.