Molekula
N-Hydroxysuccinimide (HOSu)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
N-Hydroxysuccinimide (HOSu) is a versatile chemical activator and reagent widely used in peptide synthesis, bioconjugation, and the preparation of active esters for organic chemistry. It enhances reaction efficiency by forming stable intermediates, particularly in amide bond formation. N-Hydroxysuccinimide (CAS 6066-82-6) has the molecular formula C4H5NO3 and a molecular weight of 115.09. It is stored at ambient conditions and carries no signal word under standard handling. Molekula supplies N-Hydroxysuccinimide from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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25 g — £23.00 per pack ex VAT · £27.60 inc. VAT
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100 g — £59.20 per pack ex VAT · £71.04 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to off white crystalline powder |
| Melting Point | 95-101°C |
| Loss on Drying | ≤0.50% |
| Assay (Titration) | 98.00-102.00% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
For research use only. Not for human use.
Identification
| Property | Value |
|---|---|
| SKU | 58561996 |
| CAS Number | 6066-82-6 |
| IUPAC Name | 1-hydroxypyrrolidine-2,5-dione |
| EC Number | 228-001-3 |
| Molecular Formula | C4H5NO3 |
| Molecular Weight | 115.09 |
| Exact Mass | 115.0269 |
| SMILES | C1CC(=O)N(C1=O)O |
| InChIKey | NQTADLQHYWFPDB-UHFFFAOYSA-N |
| InChI | InChI=1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2 |
| PubChem CID | 80170 |
| REACH Code | Y113 |
| TSCA Listed | Yes |
| HTS Code | 29280090 |
| Tariff Code | 2928009090 |
Safety & GHS
Detailed safety information available in the SDS — see Documents below.
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 1-Hydroxy-2,5-pyrrolidinedione
- 1-hydroxypyrrolidine-2,5-dione
- 1-Hydroxysuccinimide
- 2,5-Pyrrolidinedione, 1-hydroxy-
- HOSu
- Hydroxysuccinimide
- N-Hydroxysuccinimide
- NHS
- Succinimide, N-hydroxy-
Frequently asked questions
What is N-Hydroxysuccinimide (HOSu) commonly used for?
N-Hydroxysuccinimide is primarily used as a reagent in peptide synthesis, active ester formation, and bioconjugation reactions, such as linking biomolecules like proteins or antibodies to other molecules.
What is the chemical formula and molecular weight of N-Hydroxysuccinimide?
The chemical formula is **C₄H₅NO₃**, and the molecular weight is **115.09 g/mol**.
How should N-Hydroxysuccinimide be stored?
Store at **ambient temperature** in a tightly sealed container, away from moisture and strong oxidizing agents.
What grades or purities of N-Hydroxysuccinimide does Molekula offer?
Molekula supplies **high-purity (98%+)** N-Hydroxysuccinimide suitable for research and industrial applications.
Can Molekula supply N-Hydroxysuccinimide in bulk quantities?
Yes, Molekula can provide N-Hydroxysuccinimide in bulk, with flexible packaging options to meet your volume requirements.
What documentation is provided with an order of N-Hydroxysuccinimide?
Each order includes a **Certificate of Analysis (CoA)**, Material Safety Data Sheet (MSDS), and a product specification sheet.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.