Molekula
Fmoc-L-Arg(Pbf)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Fmoc-L-Arg(Pbf) is a protected amino acid derivative widely used in peptide synthesis, particularly for incorporating arginine residues with enhanced stability. It features an Fmoc (9-fluorenylmethyloxycarbonyl) protecting group on the alpha-amino function and a Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group on the guanidino side chain to prevent premature deprotection. This chemical has a CAS number of 154445-77-9, a molecular formula of C34H40N4O7S, and a molecular weight of 648.78 g/mol. It must be stored at -15 to -20°C and carries a **Warning** signal word for safety. Molekula supplies Fmoc-L-Arg(Pbf) from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Specifications
| Property | Value |
|---|---|
| Appearance | White powder |
| Purity (HPLC) | ≥99% |
| Loss on Drying | ≤2.0%(50 oC,2h) |
| TLC | ≥98% |
| Clarity in Solution | 0.3 gram in 2ml DMF clear solution |
| Optical Purity | ≤0.3% D-enantiomer |
| Water (KF) | ≤2.0% |
| Mass Spectrum | In accordance with the structure |
| Identification (IR) | In accordance with the structure |
| Kaiser Test | <0.05% |
| Element Analysis(C, H, N) | ≤5.0% |
| NMR | In accordance with the structure |
| Specific Rotation [ɑ] D25 | -4.5 o±1.5 o(C=4 in DMF) |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 90031747 |
| CAS Number | 154445-77-9 |
| IUPAC Name | (2S)-5-[[amino-[(2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl)sulfonylamino]methylidene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid |
| Molecular Formula | C34H40N4O7S |
| Molecular Weight | 648.78 |
| Exact Mass | 648.2618 |
| SMILES | CC1=C(C(=C(C2=C1OC(C2)(C)C)C)S(=O)(=O)NC(=NCCC[C@@H](C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)N)C |
| InChIKey | HNICLNKVURBTKV-NDEPHWFRSA-N |
| InChI | InChI=1S/C34H40N4O7S/c1-19-20(2)30(21(3)26-17-34(4,5)45-29(19)26)46(42,43)38-32(35)36-16-10-15-28(31(39)40)37-33(41)44-18-27-24-13-8-6-11-22(24)23-12-7-9-14-25(23)27/h6-9,11-14,27-28H,10,15-18H2,1-5H3,(H,37,41)(H,39,40)(H3,35,36,38)/t28-/m0/s1 |
| PubChem CID | 11354259 |
| REACH Code | Y113 |
| HTS Code | 29359020 |
| Tariff Code | 2932909099 |
Safety & GHS
-
Health Hazard
GHS07
Hazard statements
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+352 IF ON SKIN: Wash with soap and water
- P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- fmoc-arg(pbf)
- Fmoc-Arg(Pbf)-OH
- Fmoc-L-arg(pbf)-OH
- N-alpha-Fmoc-N'-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-argin
- N-alpha-Fmoc-N'-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine
- na-fmoc-ng-(2,2,4,6,7-pentamethyl-*dihydrobenzofu
- Na-Fmoc-Ng-2,2,4,6,7-pentamethyl-dihydrobenzofuran-5-sulfonyl-L-arginine
- Na-Fmoc-Nw-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
- Na-Fmoc-Nw-Pbf-L-arginine
- Nalpha-Fmoc-Nomega-Pbf-L-arginine
Frequently asked questions
What is Fmoc-L-Arg(Pbf) used for?
Fmoc-L-Arg(Pbf) is primarily used in peptide synthesis as a protected arginine building block, where the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group protects the guanidino function during solid-phase synthesis.
What is the chemical formula and molecular weight of Fmoc-L-Arg(Pbf)?
The chemical formula is **C₃₄H₄₀N₄O₇S**, and the molecular weight is **648.78 g/mol**.
How should Fmoc-L-Arg(Pbf) be stored?
Store at **-15 to -20°C** to maintain stability and prevent degradation.
What grade of Fmoc-L-Arg(Pbf) does Molekula supply?
Molekula supplies **analytical grade** and **synthetic grade** Fmoc-L-Arg(Pbf), suitable for research and peptide synthesis applications.
Can Molekula supply Fmoc-L-Arg(Pbf) in bulk?
Yes, Molekula can provide **bulk quantities** of Fmoc-L-Arg(Pbf) upon request, subject to availability and order volume.
What documentation comes with an order of Fmoc-L-Arg(Pbf)?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **batch-specific documentation** for traceability.
Ready to order or need a custom pack?
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