Molekula
Fmoc-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Fmoc-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine is a protected amino acid building block used in Fmoc solid-phase peptide synthesis to introduce arginine residues into the growing peptide chain, with the Pbf group protecting the guanidino side chain during assembly. This compound ensures controlled functionalization, improving peptide yield and purity in research and pharmaceutical applications. CAS 154445-77-9, molecular formula C34H40N4O7S, molecular weight 648.78 g/mol. Store at -15 to -20°C. Signal word: Warning. Molekula supplies Fmoc-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Specifications
| Property | Value |
|---|---|
| Appearance | White to off white powder |
| Purity (HPLC) | ≥98.5% |
| Assay (NaOH) | ≥90.0% |
| Enantiomeric Purity | ≤0.5% D-Enantiomer |
| Identification (TLC) | RF conforms to reference |
| TLC Semi-quantitative | ≤0.1% H- Arg (Pbf)-OH |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 90031137 |
| CAS Number | 154445-77-9 |
| IUPAC Name | (2S)-5-[[amino-[(2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl)sulfonylamino]methylidene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid |
| Molecular Formula | C34H40N4O7S |
| Molecular Weight | 648.78 |
| Exact Mass | 648.2618 |
| SMILES | CC1=C(C(=C(C2=C1OC(C2)(C)C)C)S(=O)(=O)NC(=NCCC[C@@H](C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)N)C |
| InChIKey | HNICLNKVURBTKV-NDEPHWFRSA-N |
| InChI | InChI=1S/C34H40N4O7S/c1-19-20(2)30(21(3)26-17-34(4,5)45-29(19)26)46(42,43)38-32(35)36-16-10-15-28(31(39)40)37-33(41)44-18-27-24-13-8-6-11-22(24)23-12-7-9-14-25(23)27/h6-9,11-14,27-28H,10,15-18H2,1-5H3,(H,37,41)(H,39,40)(H3,35,36,38)/t28-/m0/s1 |
| PubChem CID | 11354259 |
| REACH Code | Y113 |
| HTS Code | 29359020 |
| Tariff Code | 2932909099 |
Safety & GHS
-
Health Hazard
GHS07
Hazard statements
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+352 IF ON SKIN: Wash with soap and water
- P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- fmoc-arg(pbf)
- Fmoc-Arg(Pbf)-OH
- Fmoc-L-Arg(Pbf)
- Fmoc-L-arg(pbf)-OH
- N-alpha-Fmoc-N'-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-argin
- na-fmoc-ng-(2,2,4,6,7-pentamethyl-*dihydrobenzofu
- Na-Fmoc-Ng-2,2,4,6,7-pentamethyl-dihydrobenzofuran-5-sulfonyl-L-arginine
- Na-Fmoc-Nw-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
- Na-Fmoc-Nw-Pbf-L-arginine
- Nalpha-Fmoc-Nomega-Pbf-L-arginine
Frequently asked questions
What is Fmoc-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine used for?
This compound is primarily used in peptide synthesis as an Fmoc-protected arginine derivative to prevent side reactions during solid-phase peptide assembly.
What is the molecular formula and molecular weight of this compound?
The molecular formula is C₃₄H₄₀N₄O₇S, and the molecular weight is 648.78 g/mol.
How should this compound be stored?
Store at -15 to -20°C to maintain stability and prevent degradation.
What grade or purity is available for this product?
Molekula supplies this compound in analytical/peptide synthesis grade, typically ≥98% purity by HPLC.
Can Molekula supply this in bulk quantities?
Yes, bulk quantities are available upon request—contact our sales team for custom packaging and pricing.
What documentation comes with the order?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and batch-specific documentation for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.