Molekula
N-Acetyl-L-cysteine, USP grade
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
N-Acetyl-L-cysteine (NAC) is a biologically active derivative of the amino acid L-cysteine, widely used as a mucolytic agent to break down mucus in respiratory conditions, as an antioxidant, and in the production of pharmaceuticals, cosmetics, and dietary supplements. It supports glutathione synthesis, aids in heavy metal detoxification, and is employed in acetaminophen overdose treatments. This USP-grade chemical has a CAS number of 616-91-1, with the molecular formula HSCH2CH(NHCOCH3)CO2H and a molecular weight of 163.19. Store at 2 to 8°C under dry conditions, away from direct light. The product carries a signal word of *Warning* for safety classification. Molekula supplies N-Acetyl-L-cysteine, USP grade, from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to Off-white crystalline powder |
| Specific rotation | +21.0 to +27.0° |
| Total plate count | ≤ 1000CFU/g |
| Salmonella | Negative |
| pH | 2.0 to 2.8 |
| Loss on Drying | ≤ 1.0% |
| Assay | 98.0 - 102.0% (dried basis) |
| Residue on Ignition | ≤ 0.5% |
| Particle Size | 20 Mesh |
| Bulk density | 0.68g/ml |
| Residual Solvents | meets USP requirements |
| Heavy Metals (Pb) | ≤ 10ppm |
| Staphylococcus aureus | Negative |
| Total Coliforms | ≤ 10CFU/g |
| Cadmium (Cd) | ≤ 1ppm |
| Lead (Pb) | ≤ 3ppm |
| Mercury (Hg) | ≤ 0.1ppm |
| Identification (IR) | Conforms to structure |
| Arsenic trioxide (As2O3) | ≤ 1ppm |
| E. Coli | Negative |
| Mould & Yeast | ≤ 100CFU/g |
| Pseudomonas | Negative |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | White, crystalline powder |
| Odour | Slight acetic odor |
| Melting Point | 109.5 °C |
| Solubility (other solvents) | Soluble in water, alcohol, hot isopropyl alcohol, methyl acetate, and ethyl acetate |
| Vapour Pressure | 1.1 × 10⁻⁵ mmHg at 25 °C (Estimated) |
| pKa | pKa = 9.52 (at 25 °C) |
| log P (octanol/water) | -0.66 |
Source: PubChem CID 12035 (HSDB, DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 90030441 |
| CAS Number | 616-91-1 |
| IUPAC Name | (2R)-2-acetamido-3-sulfanylpropanoic acid |
| EC Number | 210-498-3 |
| Molecular Formula | HSCH2CH(NHCOCH3)CO2H |
| Molecular Weight | 163.19 |
| Exact Mass | 163.0303 |
| SMILES | CC(=O)N[C@@H](CS)C(=O)O |
| InChIKey | PWKSKIMOESPYIA-BYPYZUCNSA-N |
| InChI | InChI=1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1 |
| PubChem CID | 12035 |
| REACH Code | Y113 |
| TSCA Listed | Yes |
| HTS Code | 29309016 |
| Tariff Code | 2930901600 |
Safety & GHS
-
Health Hazard
GHS07
Hazard statements
- H319 Causes serious eye irritation
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- Acetadote
- Acetilcisteina
- acetylcysteine
- Brunac
- Fluimucetin
- L-Acetylcysteine
- mercapturic acid
- N-Acetyl-L-cysteine
- N-Acetylcysteine
- Respaire
Frequently asked questions
What is N-Acetyl-L-cysteine (NAC) commonly used for?
NAC is widely used as a mucolytic agent to break down mucus in respiratory conditions, as an antioxidant, and in the synthesis of glutathione, as well as in pharmaceutical formulations and nutritional supplements.
What is the chemical formula and molecular weight of N-Acetyl-L-cysteine?
The chemical formula is **HSCH₂CH(NHCOCH₃)CO₂H**, and the molecular weight is **163.19 g/mol**.
How should N-Acetyl-L-cysteine (USP grade) be stored?
Store at **2 to 8°C** in a dry, well-ventilated area, away from direct sunlight and incompatible substances.
What grade of N-Acetyl-L-cysteine does Molekula supply, and is USP grade available?
Molekula supplies **USP-grade N-Acetyl-L-cysteine**, meeting pharmaceutical standards for purity and quality.
Can Molekula supply N-Acetyl-L-cysteine in bulk quantities?
Yes, Molekula can supply N-Acetyl-L-cysteine in bulk, with flexible packaging options to meet your requirements.
What documentation comes with an order of N-Acetyl-L-cysteine?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **batch-specific documentation** to ensure compliance and traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.