Molekula
Isobutyl chloroformate
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Isobutyl chloroformate (CAS 543-27-1) is a reactive acyl chloride derivative used primarily as an intermediate in organic synthesis, particularly in peptide coupling and the preparation of carbamates. Its high reactivity makes it valuable in pharmaceutical and fine chemical manufacturing. This compound has a molecular formula of C5H9ClO2 and a molecular weight of 136.58 g/mol. It must be stored at ambient conditions and handled with caution, as it carries a **Danger** signal word due to its corrosive and hazardous properties. Molekula supplies isobutyl chloroformate from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Specifications
| Property | Value |
|---|---|
| Appearance | Clear liquid |
| Colour (Pt-Co) | ≤100 |
| Assay (GC) | ≥97.50% |
| Identification (IR) | Conforms |
| Acid (HCI) | ≤0.50% |
| Refractive Index (20ºC) | 1.4060 - 1.4080 |
| Diisobutyl carbonate (GC) | ≤1.0 |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Flash Point | 30 °C |
| Transport Class | 6.1 (3,8) |
| Packing Group | II |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Boiling Point | 129 °C |
| Vapour Pressure | 2.2 kPa at 20 °C |
Source: PubChem CID 62365 (ICSC)
Identification
| Property | Value |
|---|---|
| SKU | 90027263 |
| CAS Number | 543-27-1 |
| IUPAC Name | 2-methylpropyl carbonochloridate |
| EC Number | 208-840-1 |
| Molecular Formula | C5H9ClO2 |
| Molecular Weight | 136.58 |
| Exact Mass | 136.0291 |
| SMILES | CC(C)COC(=O)Cl |
| InChIKey | YOETUEMZNOLGDB-UHFFFAOYSA-N |
| InChI | InChI=1S/C5H9ClO2/c1-4(2)3-8-5(6)7/h4H,3H2,1-2H3 |
| PubChem CID | 62365 |
| UN Number | UN2742 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 2915.90.5050 |
| Tariff Code | 2915909098 |
Safety & GHS
-
Flammable
GHS02
-
Corrosive
GHS05
-
Toxic
GHS06
-
Health Hazard
GHS07
Hazard statements
- H226 Flammable liquid and vapour
- H290 May be corrosive to metals
- H302 Harmful if swallowed
- H314 (sub cat. 1B) Causes severe skin burns and eye damage
- H330 Fatal if inhaled
- H335 May cause respiratory irritation
Precautionary statements
- P210 Keep away from heat/sparks/open flames/hot surfaces - No smoking
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+330 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting
- P304+312 IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell
- P406 Store in a corrosive resistant container with a resistant inner liner
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 2-Methylpropyl carbonochloridate
- 2-Methylpropyl chloroformate
- CARBONOCHLORIDIC ACID, 2-METHYLPROPYL ESTER
- Chlorocarbonic acid isobutyl ester
- Chloroformic acid isobutyl ester
- Formic acid, chloro-, isobutyl ester
- i-Butyl chloroformate
- isobutyl carbonochloridate
- Isobutyl chloridocarbonate
- Isobutyl chlorocarbonate
Frequently asked questions
What is isobutyl chloroformate primarily used for?
Isobutyl chloroformate is commonly used as a reagent in organic synthesis, particularly for the preparation of carbamates, urethanes, and peptides.
What is the chemical formula and molecular weight of isobutyl chloroformate?
The chemical formula is **C₅H₉ClO₂**, and the molecular weight is **136.58 g/mol**.
What safety classification does isobutyl chloroformate have?
The product is labeled with the **signal word 'Danger'** due to its hazardous properties.
How should isobutyl chloroformate be stored?
Store at **ambient temperature** in a cool, dry place, away from moisture and incompatible materials.
Does Molekula supply isobutyl chloroformate in bulk quantities?
Yes, Molekula can supply isobutyl chloroformate in bulk, with quantities tailored to your requirements.
What documentation is provided with an order of isobutyl chloroformate?
Each order includes a **Certificate of Analysis (CoA)**, Material Safety Data Sheet (MSDS), and batch-specific documentation.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.