Molekula
Folliculinum (Estrone)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Folliculinum, also known as Estrone, is a naturally occurring estrogen hormone and a key component in hormonal therapies, particularly for menopausal symptoms, contraceptives, and hormone replacement treatments. It is also used in biochemical research and pharmaceutical formulations. This chemical has a CAS number of 53-16-7, with the molecular formula C18H22O2 and a molecular weight of 270.37 g/mol. It should be stored at ambient conditions and handled with caution, as it carries a signal word of Danger. Molekula supplies Folliculinum from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White or White to off white powder |
| Specific rotation | +158.0° ~ 165.0° |
| Loss on Drying | ≤0.5% |
| Solubility | Dissolve in sodium hydroxide solution, clear and transparent. |
| Assay | 97.0% ~ 103.0% |
| Related Substances | Ordinary impurties ≤2.0% |
| Residue on Ignition | ≤0.5% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Monoclinic orthorhombic crystals (alpha-form) |
| Odour | Odorless |
| Melting Point | 260.2 °C |
| Boiling Point | 445.2 °C |
| Density | 1.236 g/cm³ at 25 °C |
| Solubility (other solvents) | Slightly soluble in ethanol, ethyl ether, benzene; soluble in acetone, dioxane |
| log P (octanol/water) | 3.13 |
Source: PubChem CID 5870 (HSDB, DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 90036391 |
| CAS Number | 53-16-7 |
| IUPAC Name | (8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one |
| EC Number | 200-164-5 |
| Molecular Formula | C18H22O2 |
| Molecular Weight | 270.37 |
| Exact Mass | 270.162 |
| SMILES | C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=C3C=CC(=C4)O |
| InChIKey | DNXHEGUUPJUMQT-CBZIJGRNSA-N |
| InChI | InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1 |
| PubChem CID | 5870 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| Tariff Code | 2937230000 |
Safety & GHS
-
Serious Health Hazard
GHS08
-
Hazardous to the Environment
GHS09
Hazard statements
- H351 Suspected of causing cancer
- H360FD May damage fertility. May damage the unborn child.
- H362 May cause harm to breast-fed children
- H410 Very toxic to aquatic life with long lasting effects
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P263 Avoid contact during pregnancy/while nursing
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P308+313 IF exposed or concerned: Get medical advice/attention
- P501 Dispose of contents/container to an approved waste disposal plant
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- estrone
- estrovarin
- Estrugenone
- folliculin
- Follicunodis
- Kestrone
- Ketohydroxyestrin
- Theelin
- Thelykinin
- Tokokin
Frequently asked questions
What is Estrone (Folliculinum) used for?
Estrone is primarily used in hormone replacement therapy, as a precursor in the synthesis of other estrogens, and in research for studying reproductive biology and endocrine function.
What is the chemical formula and molecular weight of Estrone?
The chemical formula is **C₁₈H₂₂O₂**, and the molecular weight is **270.37 g/mol**.
How should Estrone be stored?
Store Estrone at **ambient temperature** in a tightly sealed container, protected from light and moisture.
What grades of Estrone does Molekula supply?
Molekula supplies Estrone in **pharmaceutical-grade** and **analytical-grade** purity, depending on the application.
Can Molekula supply Estrone in bulk quantities?
Yes, Molekula can supply Estrone in bulk, with quantities and packaging tailored to your specific needs.
What documentation comes with an order of Estrone?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **batch-specific documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.