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Molekula

Molekula

Fluticasone propionate

SKU 12221161 CAS 80474-14-2 C25H31F3O5S MW 500.57 In stock Bulk quantities on request

Supplying 4,500+ customers in over 80 countries

ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need

Fluticasone propionate is a potent synthetic glucocorticoid steroid used primarily in pharmaceutical formulations as an anti-inflammatory agent for treating respiratory conditions like asthma and allergic rhinitis. It is also applied topically for dermatological issues. This high-purity chemical has a CAS number of 80474-14-2, a molecular formula of C25H31F3O5S, and a molecular weight of 500.57 g/mol. It is stable at ambient storage conditions and carries the signal word Danger, with hazard statements H302, H317, H360, H373 and H400. Molekula supplies fluticasone propionate from research to bulk quantities with full documentation and ISO 9001:2015 traceability.

Expect a response within hours Speak to a chemist: +44 (0) 3302 000333

Example image for illustration only. Other packaging and pack sizes are available.

Pricing & pack sizes

Pack sizes & pricing

These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.

Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.

  • 1 g — £124.50 per pack ex VAT · £149.40 inc. VAT

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Specifications

Property Value
Appearance White to off-white powder
Water ≤0.20%
Specific rotation +32 to +36°
Identification IR & HPLC
Acetone ≤1.0%
Dichloromethane ≤600ppm
Methanol ≤3000ppm
Particle Size 85% <10um
Pyridine ≤200ppm
Total Impurities ≤1.20%
Any other impurity ≤0.1%
Assay HPLC 97.0 - 102.0%
Impurity D,G ≤0.3%
Impurity A,B,C,E,F,H,I ≤0.2%
Impurity with RRT1.23 ≤0.2%

Storage & handling

Property Value
Storage Temperature Ambient
Flash Point 0 °C
Transport Class 9
Packing Group III
Acidity Neutral

Literature values

Published physical properties of the substance, not batch specifications.

Property Value
Melting Point 261-273 °C

Source: PubChem CID 444036 (DrugBank)

Identification

Property Value
SKU 12221161
CAS Number 80474-14-2
IUPAC Name [(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
EC Number 617-082-4
Molecular Formula C25H31F3O5S
Molecular Weight 500.57
Exact Mass 500.1844
SMILES CCC(=O)O[C@@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)C)C(=O)SCF
InChIKey WMWTYOKRWGGJOA-CENSZEJFSA-N
InChI InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1
PubChem CID 444036
UN Number UN3077
REACH Code Y110
HTS Code 2937.22.0090
Tariff Code 2937220000

Safety & GHS

Danger
  • GHS pictogram — Health Hazard Health Hazard GHS07
  • GHS pictogram — Serious Health Hazard Serious Health Hazard GHS08
  • GHS pictogram — Hazardous to the Environment Hazardous to the Environment GHS09

Hazard statements

  • H302 Harmful if swallowed
  • H317 May cause an allergic skin reaction
  • H360 May damage fertility or the unborn child
  • H373 May cause damage to organs through prolonged or repeated exposure
  • H400 Very toxic to aquatic life

Precautionary statements

  • P260 Do not breathe dust/fume/gas/mist/vapours/spray
  • P263 Avoid contact during pregnancy/while nursing
  • P273 Avoid release to the environment
  • P280 Wear protective gloves/protective clothing/eye protection/face protection
  • P301+P312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
  • P302+352 IF ON SKIN: Wash with soap and water
  • P304+P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
  • P308+P313 IF exposed or concerned: Get medical advice/attention

Documents

Safety Data Sheets (SDS)

Available in English, German, Spanish, French, Italian, Portuguese, Arabic, Dutch.

Certificate of Analysis (CoA) by batch

Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.

Synonyms

  • Cutivate
  • Flixotide
  • Flonase
  • Flovent
  • Flovent Diskus
  • Flovent Diskus 100
  • Flovent Diskus 250
  • Flovent Diskus 50
  • Flovent HFA
  • Xhance

Frequently asked questions

What is fluticasone propionate commonly used for?

Fluticasone propionate is primarily used as a potent corticosteroid in nasal sprays, inhalers, and topical creams for treating inflammation, allergies, and asthma.

What is the chemical formula and molecular weight of fluticasone propionate?

The chemical formula is C₂₅H₃₁F₃O₅S, and the molecular weight is 500.57 g/mol.

How should fluticasone propionate be stored?

Store at ambient temperature in a dry, well-ventilated area, away from direct sunlight and moisture.

What grades or purity levels of fluticasone propionate does Molekula supply?

Molekula supplies pharmaceutical-grade (USP/EP/BP compliant) fluticasone propionate for research, development, and manufacturing applications.

Can Molekula supply fluticasone propionate in bulk quantities?

Yes, Molekula can provide bulk quantities of fluticasone propionate based on customer requirements, subject to availability and regulatory compliance.

What documentation is provided with an order of fluticasone propionate?

Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and batch-specific documentation for traceability.

Ready to order or need a custom pack?

Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.

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