Molekula
DTT (Dithiothreitol)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Dithiothreitol (DTT) is a reducing agent commonly used in biochemistry to break disulfide bonds in proteins and stabilize thiol groups. It is widely employed in protein purification, electrophoresis, and molecular biology applications. Available with a molecular formula of C4H10O2S2, molecular weight of 154.25 g/mol, and CAS number 3483-12-3. Store at 2 to 8 °C. Signal word: Danger. Molekula supplies DTT from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Often bought together
Pricing & pack sizes
In stock — dispatched within 2 working days
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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1 g — £24.00 per pack ex VAT · £28.80 inc. VAT
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5 g — £30.90 per pack ex VAT · £37.08 inc. VAT
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10 g — £45.00 per pack ex VAT · £54.00 inc. VAT
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25 g — £93.30 per pack ex VAT · £111.96 inc. VAT
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100 g — £264.90 per pack ex VAT · £317.88 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White free flowing powder |
| Melting Point | 38.0 - 44.0°C |
| Identification | Conforms to reference |
| pH | 4.0 - 6.0 (0.1M aq.) |
| Loss on Drying | ≤ 0.5% |
| Solubility | Soluble in methanol and methylene chloride, water, absolute ethanol, acetone, ethyl acetate |
| Assay | ≥ 99.0% |
| UV Absorbance | @ 500nm: ≤ 0.05, @ 280nm: ≤ 0.10 |
| Clarity | A) 5% (W/V) solution in water is clear and colourless. B) 1 molar solution in 0.01m sodium acetate at pH 5.2 should be clear and colourless |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Acidity | Neutral |
For research use only. Not for human use.
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Solid |
| Odour | Characteristic |
| Melting Point | 42.5 °C at 760 mmHg |
| Water Solubility | Freely soluble in water |
| Solubility (other solvents) | Freely soluble in ethanol, acetone, ethyl acetate, chloroform, ether |
Source: PubChem CID 439196 (HSDB, Human Metabolome Database (HMDB))
Identification
| Property | Value |
|---|---|
| SKU | 19733320 |
| CAS Number | 3483-12-3 |
| IUPAC Name | (2R,3R)-1,4-bis(sulfanyl)butane-2,3-diol |
| EC Number | 222-468-7 |
| Molecular Formula | C4H10O2S2 |
| Molecular Weight | 154.25 |
| Exact Mass | 154.0122 |
| SMILES | C([C@@H]([C@H](CS)O)O)S |
| InChIKey | VHJLVAABSRFDPM-IMJSIDKUSA-N |
| InChI | InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m0/s1 |
| PubChem CID | 439196 |
| REACH Code | Y113 |
| HTS Code | 2930.90.9255 |
| Tariff Code | 2930909599 |
Safety & GHS
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Corrosive
GHS05
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Health Hazard
GHS07
Hazard statements
- H302 Harmful if swallowed
- H315 Causes skin irritation
- H318 Causes serious eye damage
- H335 May cause respiratory irritation
- H412 Harmful to aquatic life with long lasting effects
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (2R,3R)-1,4-disulfanylbutane-2,3-diol
- 1,4-Dithiothreitol
- 2,3-Butanediol, 1,4-dimercapto-, (2R,3R)-rel-
- 2,3-Butanediol, 1,4-dimercapto-, DL-threo-
- Cleland reagent
- Cleland's reagent
- Dithiothreitol
- Dithiotreitol
- Sputolysin
- Threitol, 1,4-dithio-
Frequently asked questions
What is DTT used for?
DTT is commonly used as a reducing agent in biochemical applications, such as protein denaturation and preventing disulfide bond formation.
What is the chemical formula and molecular weight of DTT?
The formula is C4H10O2S2 and the molecular weight is 154.25 g/mol.
How should DTT be stored?
DTT should be stored at 2 to 8 °C and protected from light and moisture.
What grade of DTT does Molekula supply?
Molekula supplies DTT in high-purity grade suitable for research and laboratory use.
Can Molekula supply DTT in bulk?
Yes, Molekula can supply DTT in bulk quantities—please contact our sales team for pricing and availability.
What documentation comes with a DTT order?
Each order includes a Certificate of Analysis (CoA) and safety data sheet (SDS) with the shipment.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.