Molekula
DL-Dithiothreitol
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
DL-Dithiothreitol (DTT) is a reducing agent widely used in molecular biology to break disulfide bonds in proteins, maintaining them in a reduced state during experiments like SDS-PAGE and Western blotting. It is also employed in biochemical research to prevent protein aggregation and preserve enzyme activity. This chemical has a CAS number of 3483-12-3, with the molecular formula C4H10O2S2 and a molecular weight of 154.25 g/mol. Store DTT between 2–8°C, and handle with care as it carries a "Danger" signal word. Molekula supplies DL-Dithiothreitol from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Specifications
| Property | Value |
|---|---|
| Appearance | Solid |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Solid |
| Odour | Characteristic |
| Melting Point | 42.5 °C at 760 mmHg |
| Water Solubility | Freely soluble in water |
| Solubility (other solvents) | Freely soluble in ethanol, acetone, ethyl acetate, chloroform, ether |
Source: PubChem CID 439196 (HSDB, Human Metabolome Database (HMDB))
Identification
| Property | Value |
|---|---|
| SKU | 90029704 |
| CAS Number | 3483-12-3 |
| IUPAC Name | (2R,3R)-1,4-bis(sulfanyl)butane-2,3-diol |
| EC Number | 222-468-7 |
| Molecular Formula | C4H10O2S2 |
| Molecular Weight | 154.25 |
| Exact Mass | 154.0122 |
| SMILES | C([C@@H]([C@H](CS)O)O)S |
| InChIKey | VHJLVAABSRFDPM-IMJSIDKUSA-N |
| InChI | InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m0/s1 |
| PubChem CID | 439196 |
| REACH Code | Y113 |
| HTS Code | 2930.90.9255 |
| Tariff Code | 2930909599 |
Safety & GHS
-
Corrosive
GHS05
-
Health Hazard
GHS07
Hazard statements
- H302 Harmful if swallowed
- H315 Causes skin irritation
- H318 Causes serious eye damage
- H335 May cause respiratory irritation
- H412 Harmful to aquatic life with long lasting effects
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Quality certificates
Molekula Group is certified to ISO 9001:2015 (quality) and ISO 14001:2015 (environmental management), audited by a UKAS-accredited body. Both certificates are valid to 17 May 2028.
Synonyms
- (2R,3R)-1,4-disulfanylbutane-2,3-diol
- 1,4-Dithiothreitol
- 2,3-Butanediol, 1,4-dimercapto-, (2R,3R)-rel-
- 2,3-Butanediol, 1,4-dimercapto-, DL-threo-
- Cleland reagent
- Cleland's reagent
- Dithiothreitol
- Dithiotreitol
- Sputolysin
- Threitol, 1,4-dithio-
Frequently asked questions
What is DL-Dithiothreitol (DTT) commonly used for?
DL-Dithiothreitol (DTT) is primarily used as a reducing agent in biochemical research, particularly for reducing disulfide bonds in proteins and maintaining thiols in their reduced state.
What is the molecular formula and molecular weight of DL-Dithiothreitol?
The molecular formula of DL-Dithiothreitol is **C4H10O2S2**, and its molecular weight is **154.25 g/mol**.
How should DL-Dithiothreitol be stored?
Store DL-Dithiothreitol at **2 to 8°C** in a cool, dry place, protected from light and moisture.
What grades of DL-Dithiothreitol does Molekula supply?
Molekula supplies **analytical and biochemical grades** of DL-Dithiothreitol, suitable for research and laboratory applications.
Can Molekula supply DL-Dithiothreitol in bulk quantities?
Yes, Molekula can provide DL-Dithiothreitol in bulk, with quantities tailored to meet your specific research or industrial needs.
What documentation comes with an order of DL-Dithiothreitol?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **batch-specific documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.