Molekula
D-Proline
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
D-Proline is a naturally occurring amino acid with a pyrrolidine ring structure, widely used in pharmaceuticals, chiral synthesis, and as a catalyst in asymmetric reactions. It is used in synthetic peptide chemistry to introduce D-configured proline residues and is a critical building block in organic chemistry. Catalogue details: CAS 344-25-2, molecular formula C5H9NO2, molecular weight 115.13 g/mol. Stored at ambient conditions, with no signal word required for safety classification. Molekula supplies D-Proline from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
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5 g — $58.70 per pack
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Specifications
| Property | Value |
|---|---|
| Appearance | White or off-white crystalline powder |
| Specific rotation | +84.5 to +86.5° |
| pH | 5.9 - 6.9 |
| Loss on Drying | ≤0.5% |
| Chloride (Cl-) | ≤0.020% |
| Assay | >98.5% |
| Residue on Ignition | ≤0.5% |
| Heavy Metals (Pb) | ≤10ppm |
| Iron (Fe) | ≤10ppm |
| Arsenic (As) | ≤2ppm |
| Ammonium (NH4+) | ≤0.02% |
| Sulphates (SO4)(2-) | ≤0.020% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Melting Point | 221 °C |
Source: PubChem CID 8988 (Human Metabolome Database (HMDB))
Identification
| Property | Value |
|---|---|
| SKU | 38033125 |
| CAS Number | 344-25-2 |
| IUPAC Name | (2R)-pyrrolidine-2-carboxylic acid |
| EC Number | 206-452-7 |
| Molecular Formula | C5H9NO2 |
| Molecular Weight | 115.13 |
| Exact Mass | 115.0633 |
| SMILES | C1C[C@@H](NC1)C(=O)O |
| InChIKey | ONIBWKKTOPOVIA-SCSAIBSYSA-N |
| InChI | InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1 |
| PubChem CID | 8988 |
| REACH Code | Y113 |
| TSCA Listed | Yes |
| HTS Code | 2933999701 |
| Tariff Code | 2933998090 |
Safety & GHS
Precautionary statements
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (2R)-pyrrolidin-1-ium-2-carboxylate
- (2R)-pyrrolidine-2-carboxylic acid
- (R)-2-CARBOXYPYRROLIDINE
- (R)-PROLINE
- (R)-pyrrolidine-2-carboxylic acid
- D-Pro
- D-Prolin
- H-D-Pro-OH
- H-Pros-OH
- PROLINE, D-
Frequently asked questions
What is D-Proline commonly used for?
D-Proline is primarily used in biochemical research, peptide synthesis, and as a chiral building block in organic synthesis, including pharmaceutical and agrochemical applications.
What is the chemical formula and molecular weight of D-Proline?
The chemical formula is C₅H₉NO₂, and the molecular weight is 115.13 g/mol.
How should D-Proline be stored?
Store D-Proline at ambient temperature in a tightly sealed container, away from moisture and strong oxidizing agents.
What grades of D-Proline does Molekula offer?
Molekula supplies analytical standard (ACS grade) and research-grade D-Proline, with purity typically ≥99%.
Can Molekula supply D-Proline in bulk quantities?
Yes, Molekula can provide D-Proline in bulk, with minimum order quantities and packaging options tailored to your needs—contact us for details.
What documentation comes with a D-Proline order?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and batch-specific documentation for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.