Molekula
Amlodipine Base
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Amlodipine Base is a calcium channel blocker widely used as an active pharmaceutical ingredient (API) in antihypertensive and antianginal medications to treat high blood pressure and chest pain. It inhibits calcium influx into vascular smooth muscle and cardiac cells, promoting vasodilation and reducing cardiac workload. This chemical has a CAS number of 88150-42-9, a molecular formula of C20H25ClN2O5, and a molecular weight of 408.88 g/mol. It is stored at ambient conditions and classified with a signal word of "Danger" due to its hazardous properties. Molekula supplies Amlodipine Base from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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100 mg — £119.20 per pack ex VAT · £143.04 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to off-white powder |
| Melting Point | 137 - 142 ℃ |
| Loss on Drying | ≤1.0% |
| Solubility | Slightly soluble in water, freely soluble in acetone and alcohol |
| Assay | ≥99% |
| Individual impurity | ≤0.1% |
| Total Impurities | ≤1.0% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Transport Class | 6.1 |
| Packing Group | III |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Water Solubility | Slightly soluble in water |
| pKa | pKa = 9.26 |
| log P (octanol/water) | 3 |
Source: PubChem CID 2162 (DrugBank, ChEMBL, HSDB)
Identification
| Property | Value |
|---|---|
| SKU | 40403726 |
| CAS Number | 88150-42-9 |
| IUPAC Name | 3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate |
| EC Number | 425-820-1 |
| Molecular Formula | C20H25ClN2O5 |
| Molecular Weight | 408.88 |
| Exact Mass | 408.1452 |
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN |
| InChIKey | HTIQEAQVCYTUBX-UHFFFAOYSA-N |
| InChI | InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3 |
| PubChem CID | 2162 |
| UN Number | UN2811 |
| REACH Code | Y110 |
| HTS Code | 29333992 |
| Tariff Code | 2933399990 |
Safety & GHS
-
Corrosive
GHS05
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Toxic
GHS06
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Serious Health Hazard
GHS08
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Hazardous to the Environment
GHS09
Hazard statements
- H301 Toxic if swallowed
- H318 Causes serious eye damage
- H373 May cause damage to organs through prolonged or repeated exposure
- H410 Very toxic to aquatic life with long lasting effects
Precautionary statements
- P201 Obtain special instructions before use
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- amlodipina
- amlodipine
- Amlodipine Free Base
- Amlodipine Maleate (1:1)
- Amlodipino
- Amlodipinum
- Astudal 5
- CKD-330 COMPONENT AMLODIPINE
- Istin
- Norvasc
Frequently asked questions
What is amlodipine base commonly used for?
Amlodipine base is primarily used as an active pharmaceutical ingredient (API) in calcium channel blocker medications for treating hypertension (high blood pressure) and angina (chest pain).
What is the chemical formula and molecular weight of amlodipine base?
The chemical formula is **C20H25ClN2O5**, and the molecular weight is **408.88 g/mol**.
How should amlodipine base be stored?
Store amlodipine base at **ambient temperature**, away from moisture and direct sunlight, in a tightly sealed container.
What grades or purity levels of amlodipine base does Molekula supply?
Molekula supplies **pharmaceutical-grade amlodipine base**, meeting USP/EP/BP standards for API applications.
Can Molekula supply amlodipine base in bulk quantities?
Yes, Molekula can provide amlodipine base in bulk, with quantities tailored to meet your production or research needs.
What documentation is provided with an order of amlodipine base?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **batch-specific documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.