Molekula
alpha-Amanitine
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Alpha-amanitin is a potent cyclic octapeptide toxin found in *Amanita* mushrooms, primarily used in research as a selective inhibitor of RNA polymerase II. It is critical for studying cellular transcription mechanisms and its effects on eukaryotic cells. This chemical has a CAS number of 23109-05-9, a molecular formula of C39H54N10O14S, and a molecular weight of 918.97 g/mol. It must be stored at -15 to -20 °C and carries a "Danger" signal word due to its extreme toxicity. Molekula supplies alpha-amanitin from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
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1 mg — £227.50 per pack ex VAT · £273.00 inc. VAT
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Specifications
| Property | Value |
|---|---|
| Appearance | White lyophilised solid |
| Purity | >97% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Transport Class | 6.1 |
| Packing Group | I |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Melting Point | 254-255 °C |
Source: PubChem CID 9543442 (HSDB)
Identification
| Property | Value |
|---|---|
| SKU | 34670015 |
| CAS Number | 23109-05-9 |
| IUPAC Name | 2-[(1R,4S,8R,10S,13S,16S,27R,34S)-34-[(2S)-butan-2-yl]-13-[(2R,3R)-3,4-dihydroxybutan-2-yl]-8,22-dihydroxy-2,5,11,14,27,30,33,36,39-nonaoxo-27lambda4-thia-3,6,12,15,25,29,32,35,38-nonazapentacyclo[14.12.11.06,10.018,26.019,24]nonatriaconta-18(26),19(24),20,22-tetraen-4-yl]acetamide |
| EC Number | 245-432-2 |
| Molecular Formula | C39H54N10O14S |
| Molecular Weight | 918.97 |
| Exact Mass | 918.3542 |
| SMILES | CC[C@H](C)[C@H]1C(=O)NCC(=O)N[C@H]2C[S@@](=O)C3=C(C[C@@H](C(=O)NCC(=O)N1)NC(=O)[C@@H](NC(=O)[C@@H]4C[C@H](CN4C(=O)[C@@H](NC2=O)CC(=O)N)O)[C@@H](C)[C@H](CO)O)C5=C(N3)C=C(C=C5)O |
| InChIKey | CIORWBWIBBPXCG-SXZCQOKQSA-N |
| InChI | InChI=1S/C39H54N10O14S/c1-4-16(2)31-36(60)42-11-29(55)43-25-15-64(63)38-21(20-6-5-18(51)7-22(20)46-38)9-23(33(57)41-12-30(56)47-31)44-37(61)32(17(3)27(53)14-50)48-35(59)26-8-19(52)13-49(26)39(62)24(10-28(40)54)45-34(25)58/h5-7,16-17,19,23-27,31-32,46,50-53H,4,8-15H2,1-3H3,(H2,40,54)(H,41,57)(H,42,60)(H,43,55)(H,44,61)(H,45,58)(H,47,56)(H,48,59)/t16-,17-,19+,23-,24-,25-,26-,27-,31-,32-,64+/m0/s1 |
| PubChem CID | 9543442 |
| UN Number | UN3462 |
| REACH Code | Y110 |
| HTS Code | 2934.99.4400 |
| Tariff Code | 2934999090 |
Safety & GHS
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Toxic
GHS06
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Serious Health Hazard
GHS08
Hazard statements
- H300 Fatal if swallowed
- H373 May cause damage to organs through prolonged or repeated exposure
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P303+P361+P353 IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower
- P304+312 IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell
- P307+311 IF exposed: Call a POISON CENTER or doctor/physician
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- alpha-amanitin
- alpha-Amatoxin
- AMANITIN, .ALPHA.-
Frequently asked questions
What is alpha-Amanitine used for?
Alpha-Amanitine is primarily used in research as a potent inhibitor of RNA polymerase II, commonly employed in studies of gene expression and transcription.
What is the chemical formula and molecular weight of alpha-Amanitine?
The formula is C39H54N10O14S with a molecular weight of 918.97 g/mol.
How should alpha-Amanitine be stored?
It should be stored at temperatures between -15 and -20 °C to maintain stability and prevent degradation.
What grade of alpha-Amanitine does Molekula supply?
Molekula supplies alpha-Amanitine in research-grade purity suitable for laboratory use.
Can Molekula supply alpha-Amanitine in bulk quantities?
Yes, Molekula can supply alpha-Amanitine in bulk quantities—please contact our sales team for custom order details.
What documentation comes with an order of alpha-Amanitine?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS) for compliance and safety purposes.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.