Molekula
13-cis-Retinoic acid (Isotretinoin)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
13-cis-Retinoic acid (Isotretinoin) is a synthetic retinoid used in the treatment of severe acne and certain types of cancer. It functions as a modulator of cellular differentiation and proliferation. Available in powder form with a purity of ≥98%, it has a molecular formula of C20H28O2, a molecular weight of 300.44 g/mol, and must be stored at -15 to -20 °C. It is classified as a hazardous substance with a signal word of Danger. Molekula supplies 13-cis-Retinoic acid (Isotretinoin) from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Yellow crystalline powder |
| Impurity | Limit of Tretinoin: Max. 1.0% |
| Heavy metals | ≤ 0.002% |
| Loss on Drying | ≤ 0.5% |
| Assay | 98.0 - 102.0 % |
| Residue on Ignition | ≤ 0.1% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Transport Class | 9 |
| Packing Group | III |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Yellowish to orange crystalline powder |
| Melting Point | 174-175 °C |
| Water Solubility | Insoluble in water |
| Solubility (other solvents) | Sparingly soluble in alcohol |
| pKa | pKa = 5.15 |
Source: PubChem CID 5282379 (HSDB, ChEMBL)
Identification
| Property | Value |
|---|---|
| SKU | 38252425 |
| CAS Number | 4759-48-2 |
| IUPAC Name | (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid |
| EC Number | 225-296-0 |
| Molecular Formula | C20H28O2 |
| Molecular Weight | 300.44 |
| Exact Mass | 300.2089 |
| SMILES | CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C\C(=O)O)/C)/C |
| InChIKey | SHGAZHPCJJPHSC-XFYACQKRSA-N |
| InChI | InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14- |
| PubChem CID | 5282379 |
| UN Number | UN3077 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 2936.21.00.00 |
| Tariff Code | 2936210000 |
Safety & GHS
-
Health Hazard
GHS07
-
Serious Health Hazard
GHS08
-
Hazardous to the Environment
GHS09
Hazard statements
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
- H360 May damage fertility or the unborn child
- H400 Very toxic to aquatic life
- H410 Very toxic to aquatic life with long lasting effects
Precautionary statements
- P201 Obtain special instructions before use
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 13-cis-Retinoic acid
- 13-cis-Vitamin A acid
- Accutane
- Amnesteem
- Claravis
- Isotretinoin
- Isotrex
- Neovitamin A acid
- Roaccutane
- Sotret
Frequently asked questions
What is 13-cis-Retinoic acid used for?
It is primarily used in research related to retinoid signaling and skin biology, including studies on acne and cellular differentiation.
What is the chemical formula and molecular weight of 13-cis-Retinoic acid?
The formula is C20H28O2 with a molecular weight of 300.44 g/mol.
How should 13-cis-Retinoic acid be stored?
It must be stored at temperatures between -15 and -20 °C to maintain stability and prevent degradation.
What grade is available for 13-cis-Retinoic acid?
It is available in research-grade purity, suitable for laboratory use.
Can Molekula supply 13-cis-Retinoic acid in bulk?
Yes, bulk quantities are available upon request; please contact our sales team for pricing and availability.
What documentation comes with an order of 13-cis-Retinoic acid?
Each order includes a Certificate of Analysis (CoA) and safety data sheet (SDS) with the shipment.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.