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Molekula

Molekula

S-(-)-Nicotine

SKU 90028684 CAS 54-11-5 C10H14N2 MW 162.23 In stock Bulk quantities on request

Supplying 4,500+ customers in over 80 countries

ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need

S-(-)-Nicotine is a chiral form of nicotine, a naturally occurring alkaloid with potent pharmacological activity. It is used in research, pharmaceutical development, and nicotine replacement therapies. It also serves as the active ingredient in restricted-use insecticide products for greenhouse ornamental plants such as poinsettias and chrysanthemums. Available with a CAS number of 54-11-5, molecular formula C10H14N2, and molecular weight 162.23 g/mol. Stored at ambient temperature. Hazard classification includes signal word Danger. Molekula supplies S-(-)-Nicotine from research to bulk quantities with full documentation and ISO 9001:2015 traceability.

Expect a response within hours Speak to a chemist: +44 (0) 3302 000333

Example image for illustration only. Other packaging and pack sizes are available.

Pricing & pack sizes

Pack sizes & pricing

In stock — same-day dispatch

These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.

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  • 25 g — £93.50 per pack ex VAT · £112.20 inc. VAT

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Specifications

Property Value
Appearance Colourless to brown viscous liquid
Water 2.5% typical
Specific rotation -140 to -152
Assay (Anhydrous) 99.8% anhydrous
Assay(Hydrate) >95% typical >97%
Nicotine-trans-N-Oxide see total Nictoine-N-Oxide below (<0.05%)
Nicotine-cis-N-Oxide see total Nictoine-N-Oxide below (<0.05%)
Nornicotine ≤0.05%
Anabasine ≤0.05%
Anatabine ≤0.05%
Total Nicotine-N-Oxides ≤0.05%
Total Impurities (spec. and unspec.) ≤0.25%
Any Unidentified Impurity ≤0.05%
beta-nicotyrine ≤0.05%
Nicotine ≥95.0%

Storage & handling

Property Value
Storage Temperature Ambient
Flash Point 101 °C
Transport Class 6.1
Packing Group II
Acidity Base

Literature values

Published physical properties of the substance, not batch specifications.

Property Value
Appearance Colorless to pale yellow, oily liquid
Odour Fish-like odor when warm
Melting Point -79 °C
Boiling Point 247 °C
Density 1.01 (relative, water = 1)
Water Solubility 1000 g/L at 25 °C (miscible)
Vapour Pressure 0.006 kPa at 20 °C
Refractive Index 1.5282
pKa pKa = 8.5
log P (octanol/water) 1.17

Source: PubChem CID 89594 (HSDB, DrugBank, ICSC)

Identification

Property Value
SKU 90028684
CAS Number 54-11-5
IUPAC Name 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
EC Number 200-193-3
Molecular Formula C10H14N2
Molecular Weight 162.23
Exact Mass 162.1157
SMILES CN1CCC[C@H]1C2=CN=CC=C2
InChIKey SNICXCGAKADSCV-JTQLQIEISA-N
InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1
PubChem CID 89594
UN Number UN1654
REACH Code Y110
TSCA Listed Yes
HTS Code 29397900
Tariff Code 2939791000

Safety & GHS

Danger
  • GHS pictogram — Corrosive Corrosive GHS05
  • GHS pictogram — Toxic Toxic GHS06
  • GHS pictogram — Hazardous to the Environment Hazardous to the Environment GHS09

Hazard statements

  • H300 +H310 + H330 Fatal if swallowed, in contact with skin or if inhaled
  • H315 Causes skin irritation
  • H318 Causes serious eye damage
  • H411 Toxic to aquatic life with long lasting effects

Precautionary statements

  • P260 Do not breathe dust/fume/gas/mist/vapours/spray
  • P273 Avoid release to the environment
  • P280 Wear protective gloves/protective clothing/eye protection/face protection
  • P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
  • P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
  • P501 Dispose of contents/container to an approved waste disposal plant

Documents

Certificate of Analysis (CoA) by batch

Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.

Quality certificates

Molekula Group is certified to ISO 9001:2015 (quality) and ISO 14001:2015 (environmental management), audited by a UKAS-accredited body. Both certificates are valid to 17 May 2028.

Synonyms

  • (S)-3-(1-methylpyrrolidin-2-yl)pyridine
  • 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
  • Fumetobac
  • Habitrol
  • L-Nicotine
  • Nicocide
  • Nicoderm
  • Nicoderm Cq
  • nicotine
  • Nicotrol

Frequently asked questions

What is S-(-)-Nicotine used for?

S-(-)-Nicotine is primarily used in research applications, including studies on nicotinic acetylcholine receptors and addiction mechanisms.

What is the chemical formula and molecular weight of S-(-)-Nicotine?

The formula is C10H14N2 with a molecular weight of 162.23 g/mol.

How should S-(-)-Nicotine be stored?

It should be stored at ambient temperature, protected from light and moisture.

What grade of S-(-)-Nicotine is available?

Available in research grade; purity details are provided in the certificate of analysis.

Can Molekula supply S-(-)-Nicotine in bulk?

Yes, bulk quantities are available upon request; please contact our sales team for pricing and availability.

What documentation comes with an order of S-(-)-Nicotine?

Each order includes a certificate of analysis (CoA) and safety data sheet (SDS) with the shipment.

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