Molekula
L-Penicillamine
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
L-Penicillamine is a thiol-containing amino acid and the L-enantiomer of penicillamine. Unlike D-penicillamine, the enantiomer used clinically, L-Penicillamine is toxic because it antagonizes pyridoxine (vitamin B6), so it is not used therapeutically. It serves as a research compound, for example as the comparison enantiomer in stereochemical, pharmacological and toxicity studies of penicillamine, and as a vitamin B6 antagonist. It is also employed in research for its metal-binding and antioxidant properties. This chemical has a CAS number of 1113-41-3, molecular formula (CH₃)₂C(SH)CH(NH₂)CO₂H, and a molecular weight of 149.21 g/mol. Store it between 2–8°C, and handle with caution—it carries a Warning signal word for safety. Molekula supplies L-Penicillamine from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
On backorder — expected to ship by 21 November 2026
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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5 g — £124.50 per pack ex VAT · £149.40 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to off-white powder or crystal |
| Melting Point | 191.0°C - 195.0°C |
| Purity (HPLC) | ≥98.0% |
| Loss on Drying | ≤1.0% (105°C, 3 Hours) |
| Assay (Titration) | ≥95.0% |
| Clarity in Solution | 0.1g in 2ml H2O clear solution |
| Specific Optical Rotation[α]D20 | To be reported |
| Identification (IR, NMR, Mass spectrum) | In accordance with the structure |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 90026419 |
| CAS Number | 1113-41-3 |
| IUPAC Name | (2R)-2-amino-3-methyl-3-sulfanylbutanoic acid |
| EC Number | 214-203-9 |
| Molecular Formula | (CH3)2C(SH)CH(NH2)CO2H |
| Molecular Weight | 149.21 |
| Exact Mass | 149.051 |
| SMILES | CC(C)([C@@H](C(=O)O)N)S |
| InChIKey | VVNCNSJFMMFHPL-GSVOUGTGSA-N |
| InChI | InChI=1S/C5H11NO2S/c1-5(2,9)3(6)4(7)8/h3,9H,6H2,1-2H3,(H,7,8)/t3-/m1/s1 |
| PubChem CID | 92863 |
| REACH Code | Y110 |
| HTS Code | 2930.90.49.50 |
| Tariff Code | 2930901600 |
Safety & GHS
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Health Hazard
GHS07
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Serious Health Hazard
GHS08
Hazard statements
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
- H361 Suspected of damaging fertility or the unborn child
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P263 Avoid contact during pregnancy/while nursing
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+352 IF ON SKIN: Wash with soap and water
- P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P501 Dispose of contents/container to an approved waste disposal plant
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Quality certificates
Molekula Group is certified to ISO 9001:2015 (quality) and ISO 14001:2015 (environmental management), audited by a UKAS-accredited body. Both certificates are valid to 17 May 2028.
Synonyms
- (+)-penicillamine
- (2R)-2-amino-3-methyl-3-sulfanylbutanoic acid
- 3-Mercapto-L-valine
- 3-sulfanyl-L-valine
- L-(+)-beta-Mercaptovaline
- l-3-Mercaptovaline
- L-Pen
- r-penicillamine
- Valine, 3-mercapto-, L-
Frequently asked questions
What is L-Penicillamine primarily used for?
L-Penicillamine is used as a research compound, for example as the comparison enantiomer in studies of D-penicillamine and in toxicity studies, where it acts as a pyridoxine (vitamin B6) antagonist. It is not used therapeutically. Clinical uses such as treating Wilson's disease, cystinuria and rheumatoid arthritis belong to D-penicillamine.
What is the chemical formula and molecular weight of L-Penicillamine?
The chemical formula is (CH₃)₂C(SH)CH(NH₂)CO₂H, and the molecular weight is 149.21 g/mol.
How should L-Penicillamine be stored?
Store L-Penicillamine at 2–8°C in a cool, dry place, protected from light and moisture.
What grades of L-Penicillamine does Molekula supply?
Molekula supplies L-Penicillamine for research and industrial applications. L-Penicillamine is not a pharmaceutical substance. The USP/EP/BP Penicillamine monographs cover D-penicillamine.
Can Molekula supply L-Penicillamine in bulk quantities?
Yes, Molekula can supply L-Penicillamine in bulk, with quantities tailored to your specific requirements—please contact us for pricing and lead times.
What documentation comes with an order of L-Penicillamine?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and batch-specific documentation for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.