Molekula
TRIS (Tris(hydroxymethyl)aminomethane), ACS Grade
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
TRIS (Tris(hydroxymethyl)aminomethane), ACS Grade, is a widely used buffering agent in biochemical and molecular biology applications, including pH regulation in cell culture media, enzyme assays, and electrophoresis. It is also employed in pharmaceutical formulations, cosmetics, and as a standard in analytical chemistry. This chemical has a CAS number of 77-86-1, with the molecular formula NH2C(CH2OH)3 and a molecular weight of 121.14. It is stored at ambient conditions and carries a signal word of Warning for safety. Molekula supplies TRIS from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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1 kg — £66.70 per pack ex VAT · £80.04 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White crystalline powder |
| Assay/Purity | ≥99.8% |
| Melting Point | 168°C to 172°C |
| Grade | ACS Reagent |
| Heavy metals | ≤ 5ppm |
| pH | (5%aqueous):10.0to11.5 |
| Loss on Drying | ≤0.5% |
| Solubility | Clear, colourless |
| Residue on Ignition | ≤0.1% |
| Iron (Fe) | ≤1ppm |
| Water (KF) | ≤2% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Base |
Identification
| Property | Value |
|---|---|
| SKU | 90025403 |
| CAS Number | 77-86-1 |
| Molecular Formula | NH2C(CH2OH)3 |
| Molecular Weight | 121.14 |
| SMILES | C(C(CO)(CO)N)O |
| REACH Code | Y113 |
| TSCA Listed | Yes |
| HTS Code | 29221996 |
| Tariff Code | 2922190090 |
Safety & GHS
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Health Hazard
GHS07
Hazard statements
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
No alternate names recorded for this product.
Frequently asked questions
What is Tris(hydroxymethyl)aminomethane (TRIS) used for?
TRIS is commonly used as a buffer in biochemical and molecular biology applications, such as in gel electrophoresis, cell culture media, and enzyme assays.
What is the chemical formula and molecular weight of TRIS?
The chemical formula is **NH₂C(CH₂OH)₃**, and the molecular weight is **121.14 g/mol**.
How should TRIS (ACS Grade) be stored?
Store TRIS at **ambient temperature** in a tightly sealed container, away from strong oxidizing agents.
What grade of TRIS does Molekula supply, and is ACS Grade available?
Molekula supplies **ACS Grade TRIS**, which meets analytical standards for purity in laboratory applications.
Can Molekula supply TRIS in bulk quantities?
Yes, Molekula can provide TRIS in bulk—please contact us for specific packaging options and minimum order quantities.
What documentation comes with an order of TRIS?
Each order includes a **Certificate of Analysis (CoA)**, Material Safety Data Sheet (MSDS), and a product specification sheet.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.