Molekula
Tris-(2-carboxyethyl)phosphine hydrochloride (TCEP)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Tris-(2-carboxyethyl)phosphine hydrochloride (TCEP) is a water-soluble reducing agent widely used in biochemical research to cleave disulfide bonds in proteins, stabilize thiols, and prevent oxidation. It is also applied in peptide synthesis and as a reducing agent in electrophoretic mobility shift assays. TCEP has a CAS number of 51805-45-9, with the molecular formula C9H15O6P·HCl and a molecular weight of 286.65. It must be stored between 2 to 8°C and carries a **Danger** signal word due to its hazardous properties. Molekula supplies TCEP from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Often bought together
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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1 g — £30.90 per pack ex VAT · £37.08 inc. VAT
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5 g — £74.60 per pack ex VAT · £89.52 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to off-white crystal powder |
| Melting Point | 176°C - 186°C |
| Identification | Conforms to reference |
| Solubility | 30% clear and colourless aqueous solution |
| Assay | ≥98.0% |
| HNMR | Conforms to structure |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Transport Class | 8 |
| Packing Group | II |
| Acidity | Acid |
For research use only. Not for human use.
Identification
| Property | Value |
|---|---|
| SKU | 16589050 |
| CAS Number | 51805-45-9 |
| IUPAC Name | 3-[bis(2-carboxyethyl)phosphanyl]propanoic acid;hydrochloride |
| Molecular Formula | C9H15O6P·HCl |
| Molecular Weight | 286.65 |
| Exact Mass | 286.0373 |
| SMILES | C(CP(CCC(=O)O)CCC(=O)O)C(=O)O.Cl |
| InChIKey | PBVAJRFEEOIAGW-UHFFFAOYSA-N |
| InChI | InChI=1S/C9H15O6P.ClH/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15;/h1-6H2,(H,10,11)(H,12,13)(H,14,15);1H |
| PubChem CID | 2734570 |
| UN Number | UN3261 |
| REACH Code | Y110 |
| HTS Code | 29209051 |
| Tariff Code | 2920901090 |
Safety & GHS
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Corrosive
GHS05
Hazard statements
- H314 (sub cat. 1B) Causes severe skin burns and eye damage
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P303+361 IF ON SKIN (or hair): Remove immediately all contaminated clothing. Rinse with water/shower
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 3-[bis(2-carboxyethyl)phosphanyl]propanoic acid;hydrochloride
- 3,3',3''-Phosphinetriyltripropanoic acid hydrochloride
- C9H16ClO6P
- Propanoic acid, 3,3',3''-phosphinylidynetris-, hydrochloride (1:1)
- TCEP HCl
- TCEP Hydrochloride
- TCEP Hydrochloride (0.5M in water)
- Tris(2-carboxyethyl)phosphine hydrochloride
- Tris(2-carboxyethyl)phosphine, HCl
- Tris(carboxyethyl)phosphine hydrochloride
Frequently asked questions
What is Tris-(2-carboxyethyl)phosphine hydrochloride (TCEP) commonly used for?
TCEP is primarily used as a reducing agent in biochemical applications, such as protein denaturation, disulfide bond reduction in Western blotting, and sample preparation for mass spectrometry.
What is the chemical formula and molecular weight of TCEP?
The chemical formula is **C9H15O6P·HCl**, and the molecular weight is **286.65 g/mol**.
How should TCEP be stored?
Store TCEP at **2 to 8°C** in a cool, dry place, away from direct light and moisture.
What grades or purities of TCEP does Molekula supply?
Molekula supplies TCEP in **biochemical-grade purity**, suitable for research and laboratory applications.
Can Molekula supply TCEP in bulk quantities?
Yes, Molekula can provide TCEP in bulk, with quantities tailored to your specific requirements—please contact us for details.
What documentation comes with an order of TCEP?
Each order includes a **Certificate of Analysis (CoA)**, Material Safety Data Sheet (MSDS), and batch-specific documentation for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.