Molekula
Tetramethylsilane
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Tetramethylsilane (TMS) is a clear, volatile liquid organosilicon compound widely used as an internal reference standard in nuclear magnetic resonance (NMR) spectroscopy due to its single, sharp signal. It also serves as a calibration marker in gas chromatography and a precursor in chemical synthesis. CAS 75-76-3, molecular formula Si(CH3)4, molecular weight 88.22 g/mol. Store between 2–8 °C. Hazard classification includes a signal word of Danger (H224: extremely flammable liquid and vapour; H411: toxic to aquatic life with long-lasting effects). Molekula supplies Tetramethylsilane from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
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25 g — £51.00 per pack ex VAT · £61.20 inc. VAT
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Specifications
| Property | Value |
|---|---|
| Appearance | Clear, Colourless Liquid |
| Purity (GC) | ≥99.50% |
| Evaporation Residue | ≤0.05% |
| Refractive Index (n20/D) | 1.358 - 1.360 |
| Identification (NMR) | Conforms to structure |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Flash Point | -27 °C |
| Transport Class | 3 |
| Packing Group | I |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Volatile liquid or gas |
| Melting Point | -99.06 °C |
| Boiling Point | 26.6 °C |
| Density | 0.641 g/cm³ at 25 °C |
| Water Solubility | 19.6 mg/L at 25 °C |
| Solubility (other solvents) | Insoluble in cold concentrated sulfuric acid; soluble in most organic solvents |
| Vapour Pressure | 718 mmHg at 25 °C |
| Refractive Index | 1.3587 |
| log P (octanol/water) | 3.24 |
Source: PubChem CID 6396 (HSDB)
Identification
| Property | Value |
|---|---|
| SKU | 90035588 |
| CAS Number | 75-76-3 |
| IUPAC Name | tetramethylsilane |
| EC Number | 200-899-1 |
| Molecular Formula | Si(CH3)4 |
| Molecular Weight | 88.22 |
| Exact Mass | 88.0708 |
| SMILES | C[Si](C)(C)C |
| InChIKey | CZDYPVPMEAXLPK-UHFFFAOYSA-N |
| InChI | InChI=1S/C4H12Si/c1-5(2,3)4/h1-4H3 |
| PubChem CID | 6396 |
| UN Number | UN2749 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29319090 |
| Tariff Code | 2931900090 |
Safety & GHS
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Flammable
GHS02
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Hazardous to the Environment
GHS09
Hazard statements
- H224 Extremely flammable liquid and vapour
- H411 Toxic to aquatic life with long lasting effects
Precautionary statements
- P210 Keep away from heat/sparks/open flames/hot surfaces - No smoking
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (CH3)4Si
- Me4Si
- s16225
- Si(CH3)4
- Silane, tetramethyl-
- Silicon tetramethyl
- SiMe4
- Tetramethylsilane, NMR grade TMS
- Tetramethylsilicane
- UN 2749
Frequently asked questions
What is tetramethylsilane (TMS) commonly used for?
Tetramethylsilane is primarily used as a reference standard in NMR (Nuclear Magnetic Resonance) spectroscopy due to its single, sharp signal at 0 ppm, and as a precursor for the chemical vapour deposition of silicon carbide and other silicon-containing thin films.
What is the chemical formula and molecular weight of tetramethylsilane?
The chemical formula is Si(CH₃)₄, and the molecular weight is 88.22 g/mol.
What safety classification does tetramethylsilane fall under, and how should it be stored?
Tetramethylsilane is classified with the signal word 'Danger' (H224: extremely flammable liquid and vapour; H411: toxic to aquatic life with long-lasting effects). Store it at 2–8°C in a tightly sealed container, away from ignition sources.
Does Molekula offer tetramethylsilane in bulk quantities?
Yes, Molekula supplies tetramethylsilane in bulk quantities (contact us for minimum order quantities and pricing).
What documentation is provided with a tetramethylsilane order?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS/SDS), and a batch-specific quality report for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.