Molekula
TBTU (o-Benzotriazol-1-yl-N,N,N',N'-tetramethyluronium tetrafluoroborate)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
TBTU is a coupling reagent used in peptide synthesis and organic chemistry to facilitate amide bond formation. It is a stable, crystalline solid with the molecular formula C13H12N4O·BF4 and a molecular weight of 327.07 g/mol. It is stored at ambient temperature and is classified as dangerous due to its reactivity. TBTU is available under CAS number 125700-67-6. Molekula supplies TBTU from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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100 g — £30.90 per pack ex VAT · £37.08 inc. VAT
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1 kg — £163.40 per pack ex VAT · £196.08 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to Off-white powder |
| Melting Point | 195 - 205°C |
| Assay | ≥ 99.0% |
| Identification (IR) | Conforms to Reference |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Transport Class | 4.1 |
| Packing Group | II |
| Acidity | Acid |
Identification
| Property | Value |
|---|---|
| SKU | 39093565 |
| CAS Number | 125700-67-6 |
| IUPAC Name | [benzotriazol-1-yloxy(dimethylamino)methylidene]-dimethylazanium tetrafluoroborate |
| Molecular Formula | C13H12N4O.BF4 |
| Molecular Weight | 327.07 |
| Exact Mass | 321.1384 |
| SMILES | [B-](F)(F)(F)F.CN(C)C(=[N+](C)C)ON1C2=CC=CC=C2N=N1 |
| InChIKey | JKEKMBGUVUKMQB-UHFFFAOYSA-N |
| InChI | InChI=1S/C11H16N5O.BF4/c1-14(2)11(15(3)4)17-16-10-8-6-5-7-9(10)12-13-16;2-1(3,4)5/h5-8H,1-4H3;/q+1;-1 |
| PubChem CID | 2733207 |
| UN Number | UN1325 |
| REACH Code | Y110 |
| HTS Code | 2933997900 |
| Tariff Code | 2933998090 |
Safety & GHS
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Flammable
GHS02
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Health Hazard
GHS07
Hazard statements
- H228 Flammable solid
- H302 Harmful if swallowed
- H315 Causes skin irritation
- H317 May cause an allergic skin reaction
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
Precautionary statements
- P210 Keep away from heat/sparks/open flames/hot surfaces - No smoking
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 2-(1h-benzo[d][1,2,3]triazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
- 2-(1H-benzotriazol-1-yl)-1
- 2-(1h-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
- 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
- N,N,N',N'-Tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborate
- o-(1h-benzotriazol-1-yl)-n,n,n',n'-tetramethyluronium tetrafluoroborate
- O-(Benzotriazol-1-yl)-N,N,N',N'-tetra
- O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate
- TBTU
- TBTU Reagent
Frequently asked questions
What is TBTU used for?
TBTU is used as a coupling reagent in peptide synthesis, particularly in the formation of amide bonds.
What is the chemical formula and molecular weight of TBTU?
The formula is C13H12N4O·BF4 and the molecular weight is 327.07 g/mol.
How should TBTU be stored?
TBTU should be stored at ambient temperature, protected from moisture and light.
What grade of TBTU does Molekula supply?
Molekula supplies TBTU in high purity grade, suitable for synthetic and research applications.
Can Molekula supply TBTU in bulk?
Yes, Molekula can supply TBTU in bulk quantities—please contact our sales team for pricing and availability.
What documentation comes with a TBTU order?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS) with the shipment.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.