Molekula
Tadalafil USP
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Tadalafil USP is a potent phosphodiesterase type 5 (PDE5) inhibitor primarily used in the treatment of erectile dysfunction, pulmonary arterial hypertension, and benign prostatic hyperplasia. It is also utilized in research applications for studying vascular and smooth muscle function. This chemical has a CAS number of 171596-29-5, a molecular formula of C22H19N3O4, and a molecular weight of 389.40. It should be stored at ambient conditions and carries a signal word of "Warning" for safety. Molekula supplies Tadalafil USP from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White or almost white powder |
| Loss on Drying | ≤0.5% |
| Solubility | Freely soluble in dimethyl sulfoxide, slightly soluble in dichloromethane, practically insoluble in water |
| Assay | 97.5 - 102.5% |
| Residue on Ignition | ≤0.1% |
| Specific optical rotation | +78.0° to +84.0° |
| Residual Solvents | Methylamine ≤0.163% Methanol ≤0.3% Acetonitrile ≤0.041% Isopropanol ≤0.5% Ethyl acetate≤0.5% DMF ≤0.088% |
| HPLC | The retention time of the major peak of the Sample solution corresponds to that of the Identification solution, as obtained in the test for Enantiomeric and Diastere- omeric Purity. |
| Organic impurities | Individual impurities not more than 0.1%. Total impurities not more than 0 . 1 5 |
| Identification (IR) | The infrared absorption spectrum of the sample shall be consistent with that of the reference substance. |
| Enantiomeric | 6R,12aS diastereomer not more than 0.1%. 6S,12aS enantiomer not more than 0. 1%. 6S,12aR diastereomer not more than 0.1% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Melting Point | 301 - 302 °C |
| Water Solubility | Practically insoluble in water |
| Vapour Pressure | 2.2 × 10⁻¹⁴ mmHg at 25 °C (Estimated) |
| pKa | pKa = 0.85 |
| log P (octanol/water) | 1.42 |
Source: PubChem CID 110635 (Human Metabolome Database (HMDB), DrugBank, HSDB)
Identification
| Property | Value |
|---|---|
| SKU | 90035367 |
| CAS Number | 171596-29-5 |
| IUPAC Name | (2R,8R)-2-(1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione |
| Molecular Formula | C22H19N3O4 |
| Molecular Weight | 389.40 |
| Exact Mass | 389.1376 |
| SMILES | CN1CC(=O)N2[C@@H](C1=O)CC3=C([C@H]2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36 |
| InChIKey | WOXKDUGGOYFFRN-IIBYNOLFSA-N |
| InChI | InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1 |
| PubChem CID | 110635 |
| REACH Code | Y110 |
| HTS Code | 29349990 |
| Tariff Code | 2934999090 |
Safety & GHS
-
Health Hazard
GHS07
-
Serious Health Hazard
GHS08
Hazard statements
- H302 + H312 + H332 Harmful if swallowed, in contact with skin or if inhaled
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
- H361 Suspected of damaging fertility or the unborn child
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, English (US), French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- ADCIRCA
- CHEWTADZY
- Cialis
- ENTADFI COMPONENT TADALAFIL
- Ic351
- OPSYNVI COMPONENT TADALAFIL
- Tadalafil
- Tadalafil mylan
- Tadalafilo
- Trans-tadalafil
Frequently asked questions
What is Tadalafil USP primarily used for?
Tadalafil USP is primarily used as an active pharmaceutical ingredient (API) in the treatment of erectile dysfunction and benign prostatic hyperplasia (BPH).
What is the chemical formula and molecular weight of Tadalafil USP?
The chemical formula is **C₂₂H₁₉N₃O₄**, and the molecular weight is **389.40 g/mol**.
How should Tadalafil USP be stored?
Store Tadalafil USP at **ambient temperature** in a dry, well-ventilated area, away from direct sunlight and moisture.
What grade of Tadalafil is available from Molekula?
Molekula supplies **USP-grade Tadalafil**, meeting strict pharmaceutical standards for purity and consistency.
Can Molekula supply Tadalafil USP in bulk quantities?
Yes, Molekula can supply Tadalafil USP in **bulk quantities**, with flexible packaging options based on customer requirements.
What documentation comes with an order of Tadalafil USP?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **batch-specific documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.