Molekula
Sorafenib
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Sorafenib is a small-molecule tyrosine kinase inhibitor used primarily in oncology to treat advanced renal cell carcinoma and hepatocellular carcinoma by targeting multiple signaling pathways. It is a precise therapeutic agent with well-characterized pharmacokinetics for clinical applications. This high-purity chemical has a CAS number of 284461-73-0, a molecular formula of C21H16ClF3N4O3, and a molecular weight of 464.82 g/mol. It must be stored between 2 to 8°C, and it carries a "Danger" signal word due to its toxicity. Molekula supplies Sorafenib from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White powder |
| Water | <1.0% |
| Heavy metals | <10ppm |
| Assay | >99% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Transport Class | 9 |
| Packing Group | III |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | White solid |
| Melting Point | 205.6 °C |
Source: PubChem CID 216239 (HSDB)
Identification
| Property | Value |
|---|---|
| SKU | 39307716 |
| CAS Number | 284461-73-0 |
| IUPAC Name | 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide |
| EC Number | 608-209-4 |
| Molecular Formula | C21H16ClF3N4O3 |
| Molecular Weight | 464.82 |
| Exact Mass | 464.0863 |
| SMILES | CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F |
| InChIKey | MLDQJTXFUGDVEO-UHFFFAOYSA-N |
| InChI | InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31) |
| PubChem CID | 216239 |
| UN Number | UN3077 |
| REACH Code | Y110 |
| HTS Code | 29333999 |
| Tariff Code | 2933399990 |
Safety & GHS
-
Serious Health Hazard
GHS08
-
Hazardous to the Environment
GHS09
Hazard statements
- H360FD May damage fertility. May damage the unborn child.
- H362 May cause harm to breast-fed children
- H372 Causes damage to organs through prolonged or repeated exposure
- H410 Very toxic to aquatic life with long lasting effects
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P263 Avoid contact during pregnancy/while nursing
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P312 Call a POISON CENTER or doctor/physician if you feel unwell
- P501 Dispose of contents/container to an approved waste disposal plant
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- BA4 43 9006
- BAY 43-9006
- BAY 5459085
- BAY 673472
- C21H16ClF3N4O3
- Donafenib (Sorafenib D3)
- Sorafenib (Nexavar)
- Sorafenib free base
- sorafenib tosilate hydrate
- sorafenibum
Frequently asked questions
What is Sorafenib used for?
Sorafenib is primarily used as a **kinase inhibitor** in cancer treatment, targeting tumors such as renal cell carcinoma and hepatocellular carcinoma.
What is the chemical formula and molecular weight of Sorafenib?
The chemical formula is **C₂₁H₁₆ClF₃N₄O₃**, and the molecular weight is **464.82 g/mol**.
How should Sorafenib be stored?
Store Sorafenib at **2–8°C** to maintain stability and potency, following proper hazardous material handling protocols.
What grades or purities of Sorafenib does Molekula supply?
Molekula supplies **pharmaceutical-grade Sorafenib** with high purity, suitable for research and clinical applications.
Can Molekula supply Sorafenib in bulk quantities?
Yes, Molekula can provide Sorafenib in **bulk quantities** upon request, subject to availability and compliance with regulatory requirements.
What documentation comes with an order of Sorafenib?
Each order includes a **Certificate of Analysis (CoA)**, Material Safety Data Sheet (MSDS), and batch-specific documentation for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.