Molekula
Rapamycin
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Rapamycin is a potent immunosuppressant and mTOR inhibitor, widely used in research for its roles in cell signaling, aging studies, and anti-cancer investigations. It is also approved clinically for organ transplant rejection prevention. This macrocyclic compound has the CAS number 53123-88-9, with a molecular formula of C51H79NO13 and a molecular weight of 914.17 g/mol. It requires storage at -15 to -20°C, carries a **Danger** signal word for toxicity, and is supplied as a white to off-white solid. Molekula supplies Rapamycin from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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100 mg — £83.80 per pack ex VAT · £100.56 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to Off-white powder |
| Water | ≤ 1.0% |
| Purity (HPLC) | ≥ 98.5% (dried basis) |
| Heavy metals | ≤ 20ppm |
| Assay | 98.0 - 102.0% |
| Optical Rotation | -147 to -157° |
| Residue on Ignition | ≤ 0.15% |
| Identification (IR) | Conforms to Reference |
| Identification (HPLC) | Conforms to Reference |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Melting Point | 183-185 °C |
| log P (octanol/water) | 4.81 |
Source: PubChem CID 5284616 (HSDB)
Identification
| Property | Value |
|---|---|
| SKU | 41676136 |
| CAS Number | 53123-88-9 |
| IUPAC Name | (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone |
| EC Number | 610-965-5 |
| Molecular Formula | C51H79NO13 |
| Molecular Weight | 914.17 |
| Exact Mass | 913.5551 |
| SMILES | C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC |
| InChIKey | QFJCIRLUMZQUOT-HPLJOQBZSA-N |
| InChI | InChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,31-17+,35-25+/t30-,32-,33-,34-,36-,37+,38+,39+,40-,42+,43+,44-,46-,47+,51-/m1/s1 |
| PubChem CID | 5284616 |
| REACH Code | Y110 |
| HTS Code | 29349990 |
| Tariff Code | 2934999090 |
Safety & GHS
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Serious Health Hazard
GHS08
Hazard statements
- H351 Suspected of causing cancer
- H361 Suspected of damaging fertility or the unborn child
- H372 Causes damage to organs through prolonged or repeated exposure
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Russian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- Antibiotic AY 22989
- FYARRO
- HYFTOR
- Npc-12g
- RAPA
- rapalimus
- Rapammune
- Rapamune
- Sirolimus
- sirolimusum
Frequently asked questions
What is rapamycin commonly used for in research and pharmaceutical applications?
Rapamycin is primarily used as an immunosuppressant in organ transplantation and as a research tool to study mTOR signaling pathways, autophagy, and aging.
What is the chemical formula and molecular weight of rapamycin?
The chemical formula is **C₅₁H₇₉NO₁₃**, and the molecular weight is **914.17 g/mol**.
How should rapamycin be stored to maintain stability?
Rapamycin should be stored at **-15 to -20°C** to preserve its potency and prevent degradation.
What grades or purities of rapamycin does Molekula supply?
Molekula supplies rapamycin in **research-grade purity (≥98%)**, suitable for laboratory and preclinical studies.
Can Molekula supply rapamycin in bulk quantities for large-scale applications?
Yes, Molekula can provide rapamycin in bulk, with quantities and packaging tailored to meet your specific research or production needs.
What documentation is provided with a rapamycin order from Molekula?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **batch-specific documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.