Molekula
(R)-BoroLeu-(+)-Pinanediol-CF3COOH
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
(R)-BoroLeu-(+)-Pinanediol-CF3COOH is a pinanediol-protected alpha-aminoboronic ester trifluoroacetate salt, used as the boroleucine building block in the synthesis of bortezomib and related peptide boronic acid proteasome inhibitors, and also supplied as a bortezomib impurity reference standard (Bortezomib Impurity 38, Amino R Isomer). This compound is a crystalline solid with well-defined stereochemistry, enabling high selectivity in reactions. Catalogue details: CAS 179324-87-9, molecular formula C17H29BF3NO4, molecular weight 379.23 g/mol, and stable at ambient storage conditions. The product carries a "Warning" signal word for handling. Molekula supplies (R)-BoroLeu-(+)-Pinanediol-CF3COOH from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Specifications
| Property | Value |
|---|---|
| Appearance | White to off-white solid |
| Identification | Conforms to reference |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Acid |
Identification
| Property | Value |
|---|---|
| SKU | 89983512 |
| CAS Number | 179324-87-9 |
| IUPAC Name | (1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butan-1-amine;2,2,2-trifluoroacetic acid |
| Molecular Formula | C17H29BF3NO4 |
| Molecular Weight | 379.23 |
| Exact Mass | 379.2142 |
| SMILES | B1(O[C@@H]2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)N.C(=O)(C(F)(F)F)O |
| InChIKey | SRFQKJZNJYTMNI-CDVUYJLHSA-N |
| InChI | InChI=1S/C15H28BNO2.C2HF3O2/c1-9(2)6-13(17)16-18-12-8-10-7-11(14(10,3)4)15(12,5)19-16;3-2(4,5)1(6)7/h9-13H,6-8,17H2,1-5H3;(H,6,7)/t10-,11-,12+,13-,15-;/m0./s1 |
| PubChem CID | 44244713 |
| REACH Code | Y110 |
| HTS Code | 29061950 |
| Tariff Code | 2906190090 |
Safety & GHS
-
Health Hazard
GHS07
Hazard statements
- H302 Harmful if swallowed
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H332 Harmful if inhaled
- H335 May cause respiratory irritation
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (R)-BoroLeu-(+)-Pinanediol trifluoroacetate
- (R)-Boroleucine-(1S
- (R)-Boroleucine-(1S,2S,3R,5S)-(+)-pinanediol ester trifluoroacetate
- Bortezomib Amino R Isomer (TFA salt)
Frequently asked questions
What is (R)-BoroLeu-(+)-Pinanediol-CF3COOH used for?
This compound is used as the key boroleucine building block in the synthesis of bortezomib and related peptide boronic acid proteasome inhibitors. It is also used as a bortezomib impurity reference standard (Bortezomib Impurity 38, Amino R Isomer).
What is the chemical formula and molecular weight?
The formula is C₁₇H₂₉BF₃NO₄, and the molecular weight is 379.23 g/mol.
How should this product be stored?
Store at ambient temperature in a cool, dry place, away from incompatible substances. Avoid exposure to moisture.
What grade or purity is available for this product?
Molekula supplies this compound in research-grade purity (≥95% HPLC, unless otherwise specified). Custom purities may be discussed for bulk orders.
Can Molekula supply this product in bulk?
Yes, we offer bulk quantities upon request—contact our sales team for pricing, lead times, and documentation requirements.
What documentation comes with the order?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and batch-specific documentation. Custom certificates may be provided for bulk shipments.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.