Molekula
Proteinase K (DNA content ≤ 10 pg/mg)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Proteinase K is a highly stable serine protease used to digest proteins in molecular biology, particularly for DNA/RNA extraction and purification. It efficiently cleaves proteins at high temperatures and in the presence of detergents, making it ideal for lysis buffers and enzymatic treatments. CAS 39450-01-6, a protein of approximately 279 amino acids (about 28.9 kDa), DNA content ≤10 pg/mg, requires storage at -15 to -20°C. Signal word: Danger. Molekula supplies Proteinase K from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | white lyophilized powder |
| Activity | ≥ 30 U/mg lyophilizate |
| Solubility in water | ≥ 20 mg/ml |
| Specific Activity | ≥ 40 U/mg protein |
| Exonucleases | not detectable |
| DNA | ≤ 10 pg/mg |
| Endonucleases | not detectable |
| Ribonucleases | not detectable |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 90029284 |
| CAS Number | 39450-01-6 |
| Molecular Formula | C29H27N2O12P |
| Molecular Weight | 626.50 |
| REACH Code | Y110 |
| HTS Code | 3507.90.70.00 |
| Tariff Code | 3507909090 |
Safety & GHS
-
Health Hazard
GHS07
-
Serious Health Hazard
GHS08
Hazard statements
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
- H335 May cause respiratory irritation
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P284 Wear respiratory protection
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
No alternate names recorded for this product.
Frequently asked questions
What is Proteinase K primarily used for?
Proteinase K is primarily used for the removal of proteins (e.g., nucleases, proteases) from DNA/RNA samples during molecular biology applications like PCR, sequencing, and cloning.
What is the molecular weight of Proteinase K?
Proteinase K is an enzyme, a serine protease of about 279 amino acids, so it does not have a small-molecule chemical formula. Its molecular weight is approximately 28.9 kDa.
How should Proteinase K be stored?
Store Proteinase K at -15 to -20°C to maintain stability and activity.
What grade of Proteinase K does Molekula supply?
Molekula supplies recombinant or highly purified Proteinase K with DNA content ≤ 10 pg/mg for molecular biology applications.
Can Molekula supply Proteinase K in bulk quantities?
Yes, Molekula can provide Proteinase K in bulk—contact us for custom packaging and pricing.
What documentation comes with a Proteinase K order?
Each order includes a Certificate of Analysis (CoA), Safety Data Sheet (SDS), and batch-specific documentation confirming DNA content and enzyme activity.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.